Acetylcysteine

Product NDC
42494-435
11-digit product format
424940435
Labeler code
42494
Product ID
42494-435_a0973436-d684-4b3c-88ef-103e3005e6bf
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Acetylcysteine
Dosage form
SOLUTION
Route
RESPIRATORY (INHALATION)
Labeler
Cameron Pharmaceuticals
Application
ANDA214177
Marketing category
ANDA
Marketing start
2025-08-21
Substance
ACETYLCYSTEINE
Active strength
100 mg/mL
Pharmacologic classes
Antidote [EPC], Antidote for Acetaminophen Overdose [EPC], Decreased Respiratory Secretion Viscosity [PE], Increased Glutathione Concentration [PE], Mucolytic [EPC], Reduction Activity [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A214177-001ACETYLCYSTEINEACETYLCYSTEINE10%SOLUTION / INHALATION, ORALAN2025-03-14
A214177-002ACETYLCYSTEINEACETYLCYSTEINE20%SOLUTION / INHALATION, ORALAN2025-03-14

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A214177-001AN
A214177-002AN

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A214177-001ACETYLCYSTEINE10%SOLUTION / INHALATION, ORALAN2025-03-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02A214177-002ACETYLCYSTEINE20%SOLUTION / INHALATION, ORALAN2025-03-14011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214177-001ACETYLCYSTEINE10%SOLUTION / INHALATION, ORALAN2025-03-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214177-002ACETYLCYSTEINE20%SOLUTION / INHALATION, ORALAN2025-03-1431067a03dcf5…
2025-08-23 18:47 UTC2025-08A214177-001ACETYLCYSTEINE10%SOLUTION / INHALATION, ORALAN2025-03-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08A214177-002ACETYLCYSTEINE20%SOLUTION / INHALATION, ORALAN2025-03-146a471c1ec25d…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A214177-001ACETYLCYSTEINE10%SOLUTION / INHALATION, ORALAN2025-03-14a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A214177-002ACETYLCYSTEINE20%SOLUTION / INHALATION, ORALAN2025-03-14a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A214177-001AN1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A214177-002AN1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214177-001AN131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214177-002AN131067a03dcf5…
2025-08-23 18:47 UTC2025-08A214177-001AN16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A214177-002AN16a471c1ec25d…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A214177-001AN1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A214177-002AN1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Acetylcysteine
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ACETYLCYSTEINE100 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
WYQ7N0BPYCInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
307718Internal RxNorm lookup
307719Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
8165ad85-98e7-438f-9567-5cfda88d0ebfAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
7b19f89e-0a13-4d4e-a994-a46d39d008b9Product name120251120
13c3e0af-2da2-8aec-9e17-1afd680d80c2Product name820221116
f46c867f-cde5-4f14-a7c1-18ae3a6efd1cProduct name120160303

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
42494-435-25Acetylcysteine4 mL in 1 VIALSOLUTION41
42494-435-25Acetylcysteine25 in 1 CARTONSOLUTION251

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
42494-435-25ML - Milliliter42494-435646d81b1-9425-4d6a-9cf8-6781f073570012025-09-12

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
AcetylcysteineACETYLCYSTEINECameron Pharmaceuticals8165ad85-98e7-438f-9567-5cfda88d0ebf2025-08-26Warnings, Adverse reactionsExact identifier
application applno (ANDA): 214177
application number: ANDA214177
ndc (product): 42494-435

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
307718acetylcysteine 10 % Inhalation SolutionPSN8165ad85-98e7-438f-9567-5cfda88d0ebf1
307719acetylcysteine 20 % Inhalation SolutionPSN8165ad85-98e7-438f-9567-5cfda88d0ebf1
307718acetylcysteine 100 MG/ML Inhalation SolutionSCD8165ad85-98e7-438f-9567-5cfda88d0ebf1
307719acetylcysteine 200 MG/ML Inhalation SolutionSCD8165ad85-98e7-438f-9567-5cfda88d0ebf1
307718acetylcysteine 10 % Inhalation SolutionSY8165ad85-98e7-438f-9567-5cfda88d0ebf1
307719acetylcysteine 20 % Inhalation SolutionSY8165ad85-98e7-438f-9567-5cfda88d0ebf1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
42494-435-254249404352525 VIAL in 1 CARTON (42494-435-25) / 4 mL in 1 VIAL25 vial2025-08-21NoNoCurrent