ENTECAVIR

Product NDC
42494-458
11-digit product format
424940458
Labeler code
42494
Product ID
42494-458_3ada45bd-97aa-4713-ad29-6e462668c108
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
ENTECAVIR ANHYDROUS
Dosage form
TABLET
Route
ORAL
Labeler
Cameron Pharmaceuticals
Application
ANDA216857
Marketing category
ANDA
Marketing start
2025-05-15
Substance
ENTECAVIR ANHYDROUS
Active strength
1 mg/1
Pharmacologic classes
Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC], Nucleoside Analog [EXT], Nucleoside Reverse Transcriptase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A216857-001ENTECAVIRENTECAVIR0.5MGTABLET / ORALAB2024-12-23
A216857-002ENTECAVIRENTECAVIR1MGTABLET / ORALAB2024-12-23

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A216857-001AB
A216857-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A216857-001ENTECAVIR0.5MGTABLET / ORALAB2024-12-23011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216857-002ENTECAVIR1MGTABLET / ORALAB2024-12-23011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216857-001ENTECAVIR0.5MGTABLET / ORALAB2024-12-2331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216857-002ENTECAVIR1MGTABLET / ORALAB2024-12-2331067a03dcf5…
2025-08-23 18:47 UTC2025-08A216857-001ENTECAVIR0.5MGTABLET / ORALAB2024-12-236a471c1ec25d…
2025-08-23 18:47 UTC2025-08A216857-002ENTECAVIR1MGTABLET / ORALAB2024-12-236a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216857-001ENTECAVIR0.5MGTABLET / ORALAB2024-12-23fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216857-002ENTECAVIR1MGTABLET / ORALAB2024-12-23fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216857-001ENTECAVIR0.5MGTABLET / ORALAB2024-12-23b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216857-002ENTECAVIR1MGTABLET / ORALAB2024-12-23b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216857-001ENTECAVIR0.5MGTABLET / ORALAB2024-12-2303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216857-002ENTECAVIR1MGTABLET / ORALAB2024-12-2303ed91905a0d…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216857-001ENTECAVIR0.5MGTABLET / ORALAB2024-12-23a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216857-002ENTECAVIR1MGTABLET / ORALAB2024-12-23a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A216857-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216857-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216857-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216857-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A216857-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A216857-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216857-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216857-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216857-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216857-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216857-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216857-002AB103ed91905a0d…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216857-001AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216857-002AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
ENTECAVIR
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ENTECAVIR ANHYDROUS1 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
NNU2O4609DInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
485434Internal RxNorm lookup
485436Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
92a5bebd-6408-463d-933c-bab8338a677eAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
bf657fd6-5fee-0845-3354-1dada0e72202Product name920190701

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
42494-458-30ENTECAVIR30 in 1 BOTTLETABLET301

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
42494-458-30EA - Each42494-458a3c4e2ef-1fff-4b9a-9d84-37547557c47d12025-07-08

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EntecavirENTECAVIREpic Pharma, LLCd69451df-e204-4a5c-a2bb-9e6d4d5193022026-02-12Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216857
application number: ANDA216857
ENTECAVIRENTECAVIR ANHYDROUSCameron Pharmaceuticals92a5bebd-6408-463d-933c-bab8338a677e2025-06-05Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216857
application number: ANDA216857
ndc (product): 42494-458

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
485434entecavir 0.5 MG Oral TabletPSN92a5bebd-6408-463d-933c-bab8338a677e1
485436entecavir 1 MG Oral TabletPSN92a5bebd-6408-463d-933c-bab8338a677e1
485434entecavir 0.5 MG Oral TabletSCD92a5bebd-6408-463d-933c-bab8338a677e1
485436entecavir 1 MG Oral TabletSCD92a5bebd-6408-463d-933c-bab8338a677e1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
42494-458-304249404583030 TABLET in 1 BOTTLE (42494-458-30) 30 tablet2025-05-15NoNoCurrent