nighttime sleep aid

Product NDC
42507-033
11-digit product format
425070033
Labeler code
42507
Product ID
42507-033_cb5d207d-c077-48df-92d2-a27ef29b73bd
Type
HUMAN OTC DRUG
Nonproprietary name
Doxylamine succinate
Dosage form
TABLET
Route
ORAL
Labeler
HyVee Inc
Application
ANDA040167
Marketing category
ANDA
Marketing start
2014-12-04
Substance
DOXYLAMINE SUCCINATE
Active strength
25 mg/1
Pharmacologic classes
Antihistamine [EPC], Histamine Receptor Antagonists [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded packagepackage42507-03342507-033-73DDiscontinued by firm2026-08-07

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 24 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded productproductd630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage42507-033-73d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded productproductf5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage42507-033-73f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-31excluded productproduct2ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-31excluded packagepackage42507-033-732ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28excluded productproducta1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-28excluded packagepackage42507-033-73a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21excluded productproductcfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-21excluded packagepackage42507-033-73cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10excluded productproductcdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-10excluded packagepackage42507-033-73cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31excluded productproduct302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-31excluded packagepackage42507-033-73302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20excluded productproducted331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage42507-033-73ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-10excluded productproduct0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage42507-033-730efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08excluded productproductad56d346431e…cc804d4bbf1e…
2024-11-09 02:27 UTC · source 2024-11-08excluded packagepackage42507-033-73ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03excluded productproduct367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage42507-033-73367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09excluded productproduct557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage42507-033-73557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A040167-001DOXYLAMINE SUCCINATEDOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-1831067a03dcf5…
2025-08-23 18:47 UTC2025-08A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-186a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-1803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-182680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-185bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-1879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-181e350fbaab3a…
2024-05-31 18:47 UTC2024-05A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-188072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-185c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-185d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-184b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-1874a2ff9319b5…
2022-03-09 01:35 UTC2022-03A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-1887673890dc5c…
2021-03-12 10:30 UTC2021-03A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-185aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-188869cabd3fbd…
2020-11-12 02:37 UTC2020-11A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18c0c555d07b60…
2019-12-14 00:12 UTC2019-12A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-183f01610625f2…
2019-09-15 20:21 UTC2019-09A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18b00525d2431f…
2019-07-19 19:46 UTC2019-07A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-186a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-181c564ffb4f44…
2023-12-20 04:57 UTC2023-12A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-189b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-183f0d92c62455…
2023-05-13 08:27 UTC2023-05A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18053a50430f4f…
2023-01-26 05:58 UTC2023-01A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-183bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-183a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A040167-001DOXYLAMINE SUCCINATE25MGTABLET / ORAL1996-09-18cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
nighttime sleep aid
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DOXYLAMINE SUCCINATE25 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
V9BI9B5YI2Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1101446Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
95b12a14-21ee-431d-a892-46f8cdca2d7aAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
59361619-24d9-b610-eca6-5a7f25ed5e03Product name520240909
f4368033-af8c-41bf-a84b-ff77392b8522Product name120161229

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
42507-033-64nighttime sleep aid1 in 1 BLISTER PACKTABLET14
42507-033-64nighttime sleep aid32 in 1 CARTONTABLET324
42507-033-73nighttime sleep aid16 in 1 CARTONTABLET164
42507-033-73nighttime sleep aid1 in 1 BLISTER PACKTABLET14

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
DOXYLAMINE SUCCINATEACTIVE INGREDIENTV9BI9B5YI2NIGHTTIME SLEEP AID (DOXYLAMINE SUCCINATE) TABLET [HYVEE INC]2
DOXYLAMINEACTIVE MOIETY95QB77JKPLNIGHTTIME SLEEP AID (DOXYLAMINE SUCCINATE) TABLET [HYVEE INC]2
CALCIUM PHOSPHATE, DIBASIC, ANHYDROUSINACTIVE INGREDIENTL11K75P92JNIGHTTIME SLEEP AID (DOXYLAMINE SUCCINATE) TABLET [HYVEE INC]2
CALCIUM PHOSPHATE, DIBASIC, DIHYDRATEINACTIVE INGREDIENTO7TSZ97GEPNIGHTTIME SLEEP AID (DOXYLAMINE SUCCINATE) TABLET [HYVEE INC]2
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61UNIGHTTIME SLEEP AID (DOXYLAMINE SUCCINATE) TABLET [HYVEE INC]2
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30NIGHTTIME SLEEP AID (DOXYLAMINE SUCCINATE) TABLET [HYVEE INC]2

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 2 · 22 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
sleep aidDOXYLAMINE SUCCINATERite Aid Corporation4b5fdb06-f205-4424-b4cb-dddef921485b2026-05-27WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
sleep aidDOXYLAMINE SUCCINATEWalgreen Company489ee606-15f4-4032-a62b-35c8844f1a262026-05-08WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
nighttime sleep aidDOXYLAMINE SUCCINATEHyVee Inc95b12a14-21ee-431d-a892-46f8cdca2d7a2026-04-15WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
ndc (product): 42507-033
Sleep AidDOXYLAMINE SUCCINATEMeijer Distribution Incde0a6f68-6988-44df-9fab-b87620fd32e82026-03-24WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
NIGHTTIME SLEEP AIDDOXYLAMINE SUCCINATECVS Pharmacy05050b61-2417-48f0-9478-c39d6a3410262026-02-27WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
Unisom SleepTabsDOXYLAMINE SUCCINATEChattem, Inc.f591d52f-5610-4517-a96f-1ed63deb00bc2026-01-14WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
Good sense sleep aidDOXYLAMINE SUCCINATEL. Perrigo Companyf0a0eb93-96e0-432b-9b82-f0e891483be02025-11-14WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
Vicks ZzzQuil UltraDOXYLAMINE SUCCINATEThe Procter & Gamble Manufacturing Companyc29f6f9a-7b55-30c3-e053-2995a90a9de72025-10-02WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
Basic Care Sleep AidDOXYLAMINE SUCCINATEAmazon.com Services LLCe09cd229-638b-4065-8325-ed2c1ce2e99d2025-08-19WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
sleep aid ultraDOXYLAMINE SUCCINATEMeijer, Inc.792632af-01c1-4a9b-99f4-8eb84d0fc3892025-06-16WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
sleep aidDOXYLAMINE SUCCINATEPublix Super Markets Inc377ebf03-c1d5-4362-98b3-032206df9e8e2025-05-23WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
good sense sleep aid ultraDOXYLAMINE SUCCINATEL. Perrigo Company300826cf-6d0d-4efb-97aa-aa7dfff3add22025-04-02WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
up and up nighttime sleep aidDOXYLAMINE SUCCINATETarget Corporation24a0144d-cbfc-4d2f-873d-86adfa0468ca2025-04-02WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
CareOne Nighttime Sleep AidDOXYLAMINE SUCCINATEAmerican Sales Companyf8bfc874-53be-41e8-b59c-d538825761a82025-04-01WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
berkley and jensen sleep aidDOXYLAMINE SUCCINATEBJWC25f468a9-71d4-40f2-97bb-1c3ff5d4b7282025-03-31WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
topcare sleep aidDOXYLAMINE SUCCINATETopco Associates LLCc8b24ed8-34a1-4857-8fcb-6e3f9d4079032025-03-26WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
good sense sleep aid ultraDOXYLAMINE SUCCINATEL. Perrigo Company6907ffd1-39cb-4cc5-9c8a-bd975a5b06bd2025-03-06WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
dg health sleep aidDOXYLAMINE SUCCINATEDolgencorp Inca4c6b400-7fa6-4ad1-9d39-d34621eb91a62025-03-05WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
TopCare Sleep AidDOXYLAMINE SUCCINATETopco Associates LLC15dc89c4-b7ce-4d36-8107-f501daaf289b2025-02-16WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167
ultra sleep aidDOXYLAMINE SUCCINATEWalgreen Company90a5986d-2555-4c2d-8e41-16537ff1aa362025-02-07WarningsExact identifier
application applno (ANDA): 040167
application number: ANDA040167

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1101446doxylamine succinate 25 MG Oral TabletPSN95b12a14-21ee-431d-a892-46f8cdca2d7a4
1101446doxylamine succinate 25 MG Oral TabletSCD95b12a14-21ee-431d-a892-46f8cdca2d7a4

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
42507-033-644250700336432 BLISTER PACK in 1 CARTON (42507-033-64) / 1 TABLET in 1 BLISTER PACK32 blister pack2026-02-25NoNoCurrent
42507-033-734250700337316 in 1 CARTONHistorical