Bupropion Hydrochloride

Product NDC
42806-413
11-digit product format
428060413
Labeler code
42806
Product ID
42806-413_4bde68a6-0945-b21f-e063-6394a90a3bc4
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
bupropion hydrochloride
Dosage form
TABLET, FILM COATED, EXTENDED RELEASE
Route
ORAL
Labeler
Epic Pharma, LLC
Application
ANDA216766
Marketing category
ANDA
Marketing start
2023-02-28
Substance
BUPROPION HYDROCHLORIDE
Active strength
150 mg/1
Pharmacologic classes
Aminoketone [EPC], Dopamine Uptake Inhibitors [MoA], Increased Dopamine Activity [PE], Increased Norepinephrine Activity [PE], Norepinephrine Uptake Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A216766-001BUPROPION HYDROCHLORIDEBUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-09

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A216766-001AB2

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-09caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-09011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-0931067a03dcf5…
2025-08-23 18:47 UTC2025-08A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-096a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-09fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-09b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-0903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-092680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-095bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-09d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-09d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-0979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-09301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-091e350fbaab3a…
2024-05-31 18:47 UTC2024-05A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-098072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-096a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-091c564ffb4f44…
2023-12-20 04:57 UTC2023-12A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-09ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-09a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-099b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-09a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-093f0d92c62455…
2023-05-13 08:27 UTC2023-05A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-09053a50430f4f…
2023-01-26 05:58 UTC2023-01A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-093bdfa0b2c4d7…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216766-001BUPROPION HYDROCHLORIDE150MGTABLET, EXTENDED RELEASE / ORALAB22023-01-09a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A216766-001AB21caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A216766-001AB21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216766-001AB2131067a03dcf5…
2025-08-23 18:47 UTC2025-08A216766-001AB216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216766-001AB21fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216766-001AB21b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216766-001AB2103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216766-001AB212680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216766-001AB215bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216766-001AB21d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A216766-001AB21d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216766-001AB2179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A216766-001AB21301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A216766-001AB211e350fbaab3a…
2024-05-31 18:47 UTC2024-05A216766-001AB218072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A216766-001AB216a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A216766-001AB211c564ffb4f44…
2023-12-20 04:57 UTC2023-12A216766-001AB21ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A216766-001AB21a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A216766-001AB219b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A216766-001AB21a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A216766-001AB213f0d92c62455…
2023-05-13 08:27 UTC2023-05A216766-001AB21053a50430f4f…
2023-01-26 05:58 UTC2023-01A216766-001AB213bdfa0b2c4d7…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216766-001AB21a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Bupropion Hydrochloride
Brand name suffix
SR
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BUPROPION HYDROCHLORIDE150 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ZG7E5POY8OInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1801289Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
f56ccdb1-f9d9-3e5f-e053-2995a90a8f16Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
4eceb285-f3c7-4092-a21a-4c9f3169f20cProduct name520260220
548ba7fd-fd0c-4a21-b2b0-d01bf93143b8Product name320240209
362d7abb-94e6-4c60-9a58-266894157713Product name120231023
43a1ed49-eae2-4840-8075-cb4b33478540Product name120230425
b8ee525f-67fb-39fb-91da-7e47ac54581dProduct name520200611
2e254488-9fcb-41b3-a7c3-e2c9a3941b29Product name120200603
b4ff0805-126a-406d-9cae-fc34fd8e8889Product name120190711
816b97af-edc5-4060-aff1-b814bdbcad50Product name120190415
98e65af1-f5d0-75d5-c930-f8a4ce4c3284Product name920190211
419aab54-5d5a-4146-9453-026d4a9991beProduct name220170525
e4d463bc-c674-43cb-be06-82786f310d01Product name120150326
89dac932-b90a-4410-9ab1-84c53e57de25Product name120150316
0916dcfb-331f-89b1-8eac-6f7dc76d82daProduct name120140508
d723478e-ad4a-ec23-6bd7-cfe33e1e3840Product name120140508
d7fc3d53-5a6c-de82-2808-1780f175f17eProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
42806-413-60Bupropion HydrochlorideSR60 in 1 BOTTLETABLET, FILM COATED, EXTENDED RE605

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
42806-413-60EA - Each42806-41314b189a7-e6de-45ad-931b-26b2fd822ba012023-07-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
42806-413BUPROPION HYDROCHLORIDE SR (BUPROPION HYDROCHLORIDE) TABLET, FILM COATED, EXTENDED RELEASE [EPIC PHARMA, LLC]4Current NDC, 1 package rows20240620_f56ccdb1-f9d9-3e5f-e053-2995a90a8f16.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Bupropion Hydrochloride SRBUPROPION HYDROCHLORIDEEpic Pharma, LLCf56ccdb1-f9d9-3e5f-e053-2995a90a8f162026-02-28Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216766
application number: ANDA216766
ndc (product): 42806-413

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1801289buPROPion HCl 150 MG Smoking Cessation 12HR Extended Release Oral TabletPSNf56ccdb1-f9d9-3e5f-e053-2995a90a8f165
1801289Smoking Cessation 12 HR bupropion hydrochloride 150 MG Extended Release Oral TabletSCDf56ccdb1-f9d9-3e5f-e053-2995a90a8f165
1801289bupropion HCl 150 MG Smoking Cessation 12 HR Extended Release Oral TabletSYf56ccdb1-f9d9-3e5f-e053-2995a90a8f165
1801289buPROPion HCl 150 MG Smoking Cessation 12HR Extended Release Oral TabletPSN383728f0-dc78-49b2-86f8-4942ba7955882
1801289Smoking Cessation 12 HR bupropion hydrochloride 150 MG Extended Release Oral TabletSCD383728f0-dc78-49b2-86f8-4942ba7955882
1801289bupropion HCl 150 MG Smoking Cessation 12 HR Extended Release Oral TabletSY383728f0-dc78-49b2-86f8-4942ba7955882

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
42806-413-604280604136060 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (42806-413-60) 2023-02-28NoNoCurrent