MS Contin

Product NDC
42858-760
11-digit product format
428580760
Labeler code
42858
Product ID
42858-760_d9d3a4a4-a80c-454f-be8c-8fe0f964d139
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
morphine sulfate
Dosage form
TABLET
Route
ORAL
Labeler
Rhodes Pharmaceuticals LLC
Application
NDA019516
Marketing category
NDA
Marketing start
2017-05-15
Substance
MORPHINE SULFATE
Active strength
60 mg/1
Pharmacologic classes
Full Opioid Agonists [MoA], Opioid Agonist [EPC]
DEA schedule
CII
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 5 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N019516-001MS CONTINMORPHINE SULFATE30MGTABLET, EXTENDED RELEASE / ORALABRLD1987-05-29
N019516-002MS CONTINMORPHINE SULFATE60MGTABLET, EXTENDED RELEASE / ORALABRLD1988-04-08
N019516-003MS CONTINMORPHINE SULFATE15MGTABLET, EXTENDED RELEASE / ORALABRLD1989-09-12
N019516-004MS CONTINMORPHINE SULFATE100MGTABLET, EXTENDED RELEASE / ORALABRLD, RS1990-01-16
N019516-005MS CONTINMORPHINE SULFATE200MGTABLET, EXTENDED RELEASE / ORALABRLD1993-11-08

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 5 matching rows.

Application-product, TE code table
Application-productTE code
N019516-001AB
N019516-002AB
N019516-003AB
N019516-004AB
N019516-005AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 6 · 210 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N019516-001MS CONTIN30MGTABLET, EXTENDED RELEASE / ORALABRLD1987-05-29caaa826d4ba7…
2026-08-18 06:07:402026-07N019516-002MS CONTIN60MGTABLET, EXTENDED RELEASE / ORALABRLD1988-04-08caaa826d4ba7…
2026-08-18 06:07:402026-07N019516-003MS CONTIN15MGTABLET, EXTENDED RELEASE / ORALABRLD1989-09-12caaa826d4ba7…
2026-08-18 06:07:402026-07N019516-004MS CONTIN100MGTABLET, EXTENDED RELEASE / ORALABRLD, RS1990-01-16caaa826d4ba7…
2026-08-18 06:07:402026-07N019516-005MS CONTIN200MGTABLET, EXTENDED RELEASE / ORALABRLD1993-11-08caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N019516-001MS CONTIN30MGTABLET, EXTENDED RELEASE / ORALABRLD1987-05-29011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019516-002MS CONTIN60MGTABLET, EXTENDED RELEASE / ORALABRLD1988-04-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019516-003MS CONTIN15MGTABLET, EXTENDED RELEASE / ORALABRLD1989-09-12011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019516-004MS CONTIN100MGTABLET, EXTENDED RELEASE / ORALABRLD, RS1990-01-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019516-005MS CONTIN200MGTABLET, EXTENDED RELEASE / ORALABRLD1993-11-08011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019516-001MS CONTIN30MGTABLET, EXTENDED RELEASE / ORALABRLD1987-05-2931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019516-002MS CONTIN60MGTABLET, EXTENDED RELEASE / ORALABRLD1988-04-0831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019516-003MS CONTIN15MGTABLET, EXTENDED RELEASE / ORALABRLD1989-09-1231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019516-004MS CONTIN100MGTABLET, EXTENDED RELEASE / ORALABRLD, RS1990-01-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019516-005MS CONTIN200MGTABLET, EXTENDED RELEASE / ORALABRLD1993-11-0831067a03dcf5…
2025-08-23 18:47 UTC2025-08N019516-001MS CONTIN30MGTABLET, EXTENDED RELEASE / ORALABRLD1987-05-296a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019516-002MS CONTIN60MGTABLET, EXTENDED RELEASE / ORALABRLD1988-04-086a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019516-003MS CONTIN15MGTABLET, EXTENDED RELEASE / ORALABRLD1989-09-126a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019516-004MS CONTIN100MGTABLET, EXTENDED RELEASE / ORALABRLD, RS1990-01-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019516-005MS CONTIN200MGTABLET, EXTENDED RELEASE / ORALABRLD1993-11-086a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019516-001MS CONTIN30MGTABLET, EXTENDED RELEASE / ORALABRLD1987-05-29fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019516-002MS CONTIN60MGTABLET, EXTENDED RELEASE / ORALABRLD1988-04-08fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019516-003MS CONTIN15MGTABLET, EXTENDED RELEASE / ORALABRLD1989-09-12fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019516-004MS CONTIN100MGTABLET, EXTENDED RELEASE / ORALABRLD, RS1990-01-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019516-005MS CONTIN200MGTABLET, EXTENDED RELEASE / ORALABRLD1993-11-08fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019516-001MS CONTIN30MGTABLET, EXTENDED RELEASE / ORALABRLD1987-05-29b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019516-002MS CONTIN60MGTABLET, EXTENDED RELEASE / ORALABRLD1988-04-08b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019516-003MS CONTIN15MGTABLET, EXTENDED RELEASE / ORALABRLD1989-09-12b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019516-004MS CONTIN100MGTABLET, EXTENDED RELEASE / ORALABRLD, RS1990-01-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019516-005MS CONTIN200MGTABLET, EXTENDED RELEASE / ORALABRLD1993-11-08b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019516-001MS CONTIN30MGTABLET, EXTENDED RELEASE / ORALABRLD1987-05-2903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019516-002MS CONTIN60MGTABLET, EXTENDED RELEASE / ORALABRLD1988-04-0803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019516-003MS CONTIN15MGTABLET, EXTENDED RELEASE / ORALABRLD1989-09-1203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019516-004MS CONTIN100MGTABLET, EXTENDED RELEASE / ORALABRLD, RS1990-01-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019516-005MS CONTIN200MGTABLET, EXTENDED RELEASE / ORALABRLD1993-11-0803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019516-001MS CONTIN30MGTABLET, EXTENDED RELEASE / ORALABRLD1987-05-292680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019516-002MS CONTIN60MGTABLET, EXTENDED RELEASE / ORALABRLD1988-04-082680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019516-003MS CONTIN15MGTABLET, EXTENDED RELEASE / ORALABRLD1989-09-122680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019516-004MS CONTIN100MGTABLET, EXTENDED RELEASE / ORALABRLD, RS1990-01-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019516-005MS CONTIN200MGTABLET, EXTENDED RELEASE / ORALABRLD1993-11-082680178bc6a6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 6 · 210 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N019516-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07N019516-002AB1caaa826d4ba7…
2026-08-18 06:07:402026-07N019516-003AB1caaa826d4ba7…
2026-08-18 06:07:402026-07N019516-004AB1caaa826d4ba7…
2026-08-18 06:07:402026-07N019516-005AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N019516-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019516-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019516-003AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019516-004AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019516-005AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019516-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019516-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019516-003AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019516-004AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019516-005AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N019516-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019516-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019516-003AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019516-004AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019516-005AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019516-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019516-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019516-003AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019516-004AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019516-005AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019516-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019516-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019516-003AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019516-004AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019516-005AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019516-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019516-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019516-003AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019516-004AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019516-005AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019516-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019516-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019516-003AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019516-004AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019516-005AB12680178bc6a6…

Additional Listing Data#

Finished product
Yes
Brand name base
MS Contin
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
MORPHINE SULFATE60 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
X3P646A2J0Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 10 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
891874Internal RxNorm lookup
891881Internal RxNorm lookup
891888Internal RxNorm lookup
891893Internal RxNorm lookup
892560Internal RxNorm lookup
892574Internal RxNorm lookup
892646Internal RxNorm lookup
892648Internal RxNorm lookup
892660Internal RxNorm lookup
894813Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
c354b3bf-86c0-4bb8-8b1f-be2164942698Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
89941d4c-522d-cee0-b273-43cfa7ef6d35Product name420250516
f15f9e76-db42-8a50-218a-5ef5affa58daProduct name420240216
944b0689-73f4-6a2f-c654-1180896353c0Product name420220210
67e166c6-23d4-4709-b77d-5ca6182dcae0Product name120180830
c573a64c-fe17-2eac-fbcb-788868b4ff6bProduct name920180619
7c1819cf-69a0-41dc-aeaa-a820729bc959Product name120170406
7a68fc31-10e5-df04-67e0-3a613a2d4d2eProduct name520161114
175682a8-c657-45a2-9dfb-c565306b03c8Product name120160112
b73dadd0-1b4a-4f88-956f-a2be216c8fadProduct name120151123
4c272b1c-87fc-ebc0-994d-ac28b1e0416eProduct name120140508
7a537f54-d322-5e54-a3a2-035d3e21c3c6Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
42858-760-01MS Contin100 in 1 BOTTLE, PLASTICTABLET10016

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
42858-760-01EA - Each42858-76059e2b0d9-f456-429c-9201-d8966fd03b6812017-06-15

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
42858-760MS CONTIN (MORPHINE SULFATE) TABLET [RHODES PHARMACEUTICALS L.P.]13Current NDC, Legacy NDC, 1 package rows20250410_c354b3bf-86c0-4bb8-8b1f-be2164942698.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
MS ContinMORPHINE SULFATERhodes Pharmaceuticals LLCc354b3bf-86c0-4bb8-8b1f-be21649426982026-05-18Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 019516
application number: NDA019516
ndc (product): 42858-760

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
891874morphine sulfate 100 MG Extended Release Oral TabletPSNc354b3bf-86c0-4bb8-8b1f-be216494269816
891881morphine sulfate 15 MG Extended Release Oral TabletPSNc354b3bf-86c0-4bb8-8b1f-be216494269816
892646morphine sulfate 200 MG Extended Release Oral TabletPSNc354b3bf-86c0-4bb8-8b1f-be216494269816
891888morphine sulfate 30 MG Extended Release Oral TabletPSNc354b3bf-86c0-4bb8-8b1f-be216494269816
891893morphine sulfate 60 MG Extended Release Oral TabletPSNc354b3bf-86c0-4bb8-8b1f-be216494269816
892560MS Contin 100 MG Extended Release Oral TabletPSNc354b3bf-86c0-4bb8-8b1f-be216494269816
892574MS Contin 15 MG Extended Release Oral TabletPSNc354b3bf-86c0-4bb8-8b1f-be216494269816
892648MS Contin 200 MG Extended Release Oral TabletPSNc354b3bf-86c0-4bb8-8b1f-be216494269816
892660MS Contin 30 MG Extended Release Oral TabletPSNc354b3bf-86c0-4bb8-8b1f-be216494269816
894813MS Contin 60 MG Extended Release Oral TabletPSNc354b3bf-86c0-4bb8-8b1f-be216494269816
892560morphine sulfate 100 MG Extended Release Oral Tablet [MS Contin]SBDc354b3bf-86c0-4bb8-8b1f-be216494269816
892574morphine sulfate 15 MG Extended Release Oral Tablet [MS Contin]SBDc354b3bf-86c0-4bb8-8b1f-be216494269816
892648morphine sulfate 200 MG Extended Release Oral Tablet [MS Contin]SBDc354b3bf-86c0-4bb8-8b1f-be216494269816
892660morphine sulfate 30 MG Extended Release Oral Tablet [MS Contin]SBDc354b3bf-86c0-4bb8-8b1f-be216494269816
894813morphine sulfate 60 MG Extended Release Oral Tablet [MS Contin]SBDc354b3bf-86c0-4bb8-8b1f-be216494269816
891874morphine sulfate 100 MG Extended Release Oral TabletSCDc354b3bf-86c0-4bb8-8b1f-be216494269816
891881morphine sulfate 15 MG Extended Release Oral TabletSCDc354b3bf-86c0-4bb8-8b1f-be216494269816
892646morphine sulfate 200 MG Extended Release Oral TabletSCDc354b3bf-86c0-4bb8-8b1f-be216494269816
891888morphine sulfate 30 MG Extended Release Oral TabletSCDc354b3bf-86c0-4bb8-8b1f-be216494269816
891893morphine sulfate 60 MG Extended Release Oral TabletSCDc354b3bf-86c0-4bb8-8b1f-be216494269816
891874MS 100 MG Extended Release Oral TabletSYc354b3bf-86c0-4bb8-8b1f-be216494269816
892560MS 100 MG Extended Release Oral Tablet [MS Contin]SYc354b3bf-86c0-4bb8-8b1f-be216494269816
891881MS 15 MG Extended Release Oral TabletSYc354b3bf-86c0-4bb8-8b1f-be216494269816
892574MS 15 MG Extended Release Oral Tablet [MS Contin]SYc354b3bf-86c0-4bb8-8b1f-be216494269816
892646MS 200 MG Extended Release Oral TabletSYc354b3bf-86c0-4bb8-8b1f-be216494269816
892648MS 200 MG Extended Release Oral Tablet [MS Contin]SYc354b3bf-86c0-4bb8-8b1f-be216494269816
891888MS 30 MG Extended Release Oral TabletSYc354b3bf-86c0-4bb8-8b1f-be216494269816
892660MS 30 MG Extended Release Oral Tablet [MS Contin]SYc354b3bf-86c0-4bb8-8b1f-be216494269816
891893MS 60 MG Extended Release Oral TabletSYc354b3bf-86c0-4bb8-8b1f-be216494269816
894813MS 60 MG Extended Release Oral Tablet [MS Contin]SYc354b3bf-86c0-4bb8-8b1f-be216494269816
892560MS Contin 100 MG Extended Release Oral TabletSYc354b3bf-86c0-4bb8-8b1f-be216494269816
892574MS Contin 15 MG Extended Release Oral TabletSYc354b3bf-86c0-4bb8-8b1f-be216494269816
892648MS Contin 200 MG Extended Release Oral TabletSYc354b3bf-86c0-4bb8-8b1f-be216494269816
892660MS Contin 30 MG Extended Release Oral TabletSYc354b3bf-86c0-4bb8-8b1f-be216494269816
894813MS Contin 60 MG Extended Release Oral TabletSYc354b3bf-86c0-4bb8-8b1f-be216494269816

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
42858-760-0142858076001100 TABLET in 1 BOTTLE, PLASTIC (42858-760-01) 100 tablet2017-05-150000-00-00NoNoCurrent
42858-760-5042858076050500 TABLET in 1 BOTTLE, PLASTIC (42858-760-50) 500 tablet2017-05-150000-00-00NoNoCurrent