Metformin Hydrochloride

Product NDC
43353-128
11-digit product format
433530128
Labeler code
43353
Product ID
43353-128_2ac9368a-7105-4d2a-a6d7-a8b9c5c9bfce
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Metformin Hydrochloride
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Aphena Pharma Solutions - Tennessee, LLC
Application
ANDA091184
Marketing category
ANDA
Marketing start
2011-01-31
Marketing end
0000-00-00
Substance
METFORMIN HYDROCHLORIDE
Active strength
1000 mg/1
Pharmacologic classes
Biguanide [EPC],Biguanides [CS]
NDC exclude flag
No
Listing certified through
2020-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 3 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct43353-128DDiscontinued by firm2026-08-10
excluded packagepackage43353-12843353-128-60DDiscontinued by firm2026-08-10
excluded packagepackage43353-12843353-128-80DDiscontinued by firm2026-08-10

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A091184-001METFORMIN HYDROCHLORIDEMETFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-01
A091184-002METFORMIN HYDROCHLORIDEMETFORMIN HYDROCHLORIDE850MGTABLET / ORALAB2010-11-01
A091184-003METFORMIN HYDROCHLORIDEMETFORMIN HYDROCHLORIDE1GMTABLET / ORALAB2010-11-01

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
A091184-001AB
A091184-002AB
A091184-003AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A091184-001METFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02A091184-002METFORMIN HYDROCHLORIDE850MGTABLET / ORALAB2010-11-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02A091184-003METFORMIN HYDROCHLORIDE1GMTABLET / ORALAB2010-11-01011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A091184-001METFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A091184-002METFORMIN HYDROCHLORIDE850MGTABLET / ORALAB2010-11-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A091184-003METFORMIN HYDROCHLORIDE1GMTABLET / ORALAB2010-11-0131067a03dcf5…
2025-08-23 18:47 UTC2025-08A091184-001METFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-016a471c1ec25d…
2025-08-23 18:47 UTC2025-08A091184-002METFORMIN HYDROCHLORIDE850MGTABLET / ORALAB2010-11-016a471c1ec25d…
2025-08-23 18:47 UTC2025-08A091184-003METFORMIN HYDROCHLORIDE1GMTABLET / ORALAB2010-11-016a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A091184-001METFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-01fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A091184-002METFORMIN HYDROCHLORIDE850MGTABLET / ORALAB2010-11-01fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A091184-003METFORMIN HYDROCHLORIDE1GMTABLET / ORALAB2010-11-01fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A091184-001METFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-01b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A091184-002METFORMIN HYDROCHLORIDE850MGTABLET / ORALAB2010-11-01b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A091184-003METFORMIN HYDROCHLORIDE1GMTABLET / ORALAB2010-11-01b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A091184-001METFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-0103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A091184-002METFORMIN HYDROCHLORIDE850MGTABLET / ORALAB2010-11-0103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A091184-003METFORMIN HYDROCHLORIDE1GMTABLET / ORALAB2010-11-0103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A091184-001METFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-012680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A091184-002METFORMIN HYDROCHLORIDE850MGTABLET / ORALAB2010-11-012680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A091184-003METFORMIN HYDROCHLORIDE1GMTABLET / ORALAB2010-11-012680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A091184-001METFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-015bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A091184-002METFORMIN HYDROCHLORIDE850MGTABLET / ORALAB2010-11-015bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A091184-003METFORMIN HYDROCHLORIDE1GMTABLET / ORALAB2010-11-015bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A091184-001METFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-01d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A091184-002METFORMIN HYDROCHLORIDE850MGTABLET / ORALAB2010-11-01d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A091184-003METFORMIN HYDROCHLORIDE1GMTABLET / ORALAB2010-11-01d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A091184-001METFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-01d06236e962d9…
2024-10-29 15:01 UTC2024-10A091184-002METFORMIN HYDROCHLORIDE850MGTABLET / ORALAB2010-11-01d06236e962d9…
2024-10-29 15:01 UTC2024-10A091184-003METFORMIN HYDROCHLORIDE1GMTABLET / ORALAB2010-11-01d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A091184-001METFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-0179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A091184-002METFORMIN HYDROCHLORIDE850MGTABLET / ORALAB2010-11-0179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A091184-003METFORMIN HYDROCHLORIDE1GMTABLET / ORALAB2010-11-0179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A091184-001METFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-01301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A091184-002METFORMIN HYDROCHLORIDE850MGTABLET / ORALAB2010-11-01301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A091184-003METFORMIN HYDROCHLORIDE1GMTABLET / ORALAB2010-11-01301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A091184-001METFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-011e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A091184-002METFORMIN HYDROCHLORIDE850MGTABLET / ORALAB2010-11-011e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A091184-003METFORMIN HYDROCHLORIDE1GMTABLET / ORALAB2010-11-011e350fbaab3a…
2024-05-31 18:47 UTC2024-05A091184-001METFORMIN HYDROCHLORIDE500MGTABLET / ORALAB2010-11-018072bd15b7f6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A091184-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A091184-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A091184-003AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A091184-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A091184-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A091184-003AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A091184-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A091184-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A091184-003AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A091184-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A091184-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A091184-003AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A091184-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A091184-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A091184-003AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A091184-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A091184-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A091184-003AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A091184-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A091184-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A091184-003AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A091184-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A091184-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A091184-003AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A091184-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A091184-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A091184-003AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A091184-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A091184-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A091184-003AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A091184-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A091184-002AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A091184-003AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A091184-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A091184-002AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A091184-003AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A091184-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A091184-002AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A091184-003AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A091184-001AB18072bd15b7f6…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
43353-128-60EA - Each43353-1285e662de4-c1ab-4580-95ed-f5bd917928ea12016-07-19
43353-128-80EA - Each43353-128899e7721-a334-4f3a-870b-15dd74e29ed412016-07-19

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
43353-128METFORMIN HYDROCHLORIDE TABLET, FILM COATED [APHENA PHARMA SOLUTIONS - TENNESSEE, LLC]1Legacy NDC20160712_3395325a-35bd-4bda-bed3-81eb6153ed12.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Metformin HydrochlorideMETFORMIN HYDROCHLORIDEAscend Laboratories, LLC0ff1ba75-3c86-4baf-a6b1-1bb8838398662025-12-18Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 091184
application number: ANDA091184

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
43353-128-604335301286090 TABLET, FILM COATED in 1 BOTTLE (43353-128-60) 2015-12-260000-00-00NoNoCurrent
43353-128-8043353012880180 TABLET, FILM COATED in 1 BOTTLE (43353-128-80) 2015-12-230000-00-00NoNoCurrent