Nicardipine Hydrochloride in Sodium Chloride

Product NDC
44567-851
11-digit product format
445670851
Labeler code
44567
Product ID
44567-851_9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Nicardipine Hydrochloride
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
WG Critical Care, LLC
Application
ANDA203978
Marketing category
ANDA
Marketing start
2025-07-10
Substance
NICARDIPINE HYDROCHLORIDE
Active strength
.2 mg/mL
Pharmacologic classes
Calcium Channel Antagonists [MoA], Cytochrome P450 2C19 Inhibitors [MoA], Cytochrome P450 2C8 Inhibitors [MoA], Cytochrome P450 2D6 Inhibitors [MoA], Cytochrome P450 3A4 Inhibitors [MoA], Dihydropyridine Calcium Channel Blocker [EPC], Dihydropyridines [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDENICARDIPINE HYDROCHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17
A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDENICARDIPINE HYDROCHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A203978-001AP
A203978-002AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17011fe1cb6892…
2026-02-19 14:30 UTC2026-02A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-1731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-1731067a03dcf5…
2025-08-23 18:47 UTC2025-08A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-176a471c1ec25d…
2025-08-23 18:47 UTC2025-08A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-176a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-1703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-1703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-172680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-172680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-175bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-175bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17d06236e962d9…
2024-10-29 15:01 UTC2024-10A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-1779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-1779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-171e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-171e350fbaab3a…
2024-05-31 18:47 UTC2024-05A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-178072bd15b7f6…
2024-05-31 18:47 UTC2024-05A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-178072bd15b7f6…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A203978-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A203978-002AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203978-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203978-002AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A203978-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A203978-002AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203978-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203978-002AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203978-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203978-002AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203978-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203978-002AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203978-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203978-002AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203978-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203978-002AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203978-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203978-002AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A203978-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A203978-002AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203978-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203978-002AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203978-001AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203978-002AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203978-001AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203978-002AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A203978-001AP18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A203978-002AP18072bd15b7f6…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A203978-001AP1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A203978-002AP1a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Nicardipine Hydrochloride in Sodium ChlorideNICARDIPINE HYDROCHLORIDEWG Critical Care, LLC9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d2025-06-30Warnings, Adverse reactionsExact identifier
application applno (ANDA): 203978
application number: ANDA203978
ndc (product): 44567-851

Additional Listing Data#

Finished product
Yes
Brand name base
Nicardipine Hydrochloride in Sodium Chloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
NICARDIPINE HYDROCHLORIDE.2 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
K5BC5011K3Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
858599Internal RxNorm lookup
858603Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9ffe6b6f-b8bc-413f-9bec-7639e9d71d3dAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
31746078-c5c3-4387-a2ed-bd3c8b244c53Product name220250325
037c6bd8-1c81-7b8c-8280-c83d993a1f03Product name220250203
c9eb0343-053f-7f78-730f-1be02ab91c6cProduct name520250130

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
44567-851-01Nicardipine Hydrochloride in Sodium Chloride200 mL in 1 BAGINJECTION, SOLUTION2001
44567-851-12Nicardipine Hydrochloride in Sodium Chloride12 in 1 CARTONINJECTION, SOLUTION121

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
44567-851-01ML - Milliliter44567-85162f03ce1-723f-41c9-a287-af7b39541fd512025-10-14
44567-851-12ML - Milliliter44567-85137eb509b-2b08-4755-93c3-34e5f873eac812025-10-14

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
858599niCARdipine HCl 20 MG in 200 ML InjectionPSN9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d1
858603niCARdipine HCl 40 MG in 200 ML InjectionPSN9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d1
858599200 ML nicardipine hydrochloride 0.1 MG/ML InjectionSCD9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d1
858603200 ML nicardipine hydrochloride 0.2 MG/ML InjectionSCD9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d1
858599nicardipine hydrochloride 20 MG per 200 ML InjectionSY9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d1
858603nicardipine hydrochloride 40 MG per 200 ML InjectionSY9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
44567-851-0144567085101200 mL in 1 BAG200 mlHistorical
44567-851-124456708511212 BAG in 1 CARTON (44567-851-12) / 200 mL in 1 BAG (44567-851-01) 12 bag2025-07-10NoNoCurrent