Nicardipine Hydrochloride in Sodium Chloride

Product NDC
44567-851
11-digit product format
445670851
Labeler code
44567
Product ID
44567-851_9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Nicardipine Hydrochloride
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
WG Critical Care, LLC
Application
ANDA203978
Marketing category
ANDA
Marketing start
2025-07-10
Substance
NICARDIPINE HYDROCHLORIDE
Active strength
.2 mg/mL
Pharmacologic classes
Calcium Channel Antagonists [MoA], Cytochrome P450 2C19 Inhibitors [MoA], Cytochrome P450 2C8 Inhibitors [MoA], Cytochrome P450 2D6 Inhibitors [MoA], Cytochrome P450 3A4 Inhibitors [MoA], Dihydropyridine Calcium Channel Blocker [EPC], Dihydropyridines [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDENICARDIPINE HYDROCHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17
A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDENICARDIPINE HYDROCHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A203978-001AP
A203978-002AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17caaa826d4ba7…
2026-08-18 06:07:402026-07A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17011fe1cb6892…
2026-02-19 14:30 UTC2026-02A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-1731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-1731067a03dcf5…
2025-08-23 18:47 UTC2025-08A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-176a471c1ec25d…
2025-08-23 18:47 UTC2025-08A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-176a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-1703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-1703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-172680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-172680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-175bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-175bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17d06236e962d9…
2024-10-29 15:01 UTC2024-10A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-1779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-1779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-171e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-171e350fbaab3a…
2024-05-31 18:47 UTC2024-05A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-178072bd15b7f6…
2024-05-31 18:47 UTC2024-05A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-178072bd15b7f6…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A203978-001NICARDIPINE HYDROCHLORIDE IN 0.86% SODIUM CHLORIDE20MG/200ML (0.1MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A203978-002NICARDIPINE HYDROCHLORIDE IN 0.83% SODIUM CHLORIDE40MG/200ML (0.2MG/ML)INJECTABLE / INTRAVENOUSAP2024-04-17a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A203978-001AP1caaa826d4ba7…
2026-08-18 06:07:402026-07A203978-002AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A203978-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A203978-002AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203978-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203978-002AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A203978-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A203978-002AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203978-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203978-002AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203978-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203978-002AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203978-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203978-002AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203978-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203978-002AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203978-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203978-002AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203978-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203978-002AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A203978-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A203978-002AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203978-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203978-002AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203978-001AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203978-002AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203978-001AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203978-002AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A203978-001AP18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A203978-002AP18072bd15b7f6…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A203978-001AP1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A203978-002AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Nicardipine Hydrochloride in Sodium Chloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
NICARDIPINE HYDROCHLORIDE.2 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
K5BC5011K3Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
858599Internal RxNorm lookup
858603Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9ffe6b6f-b8bc-413f-9bec-7639e9d71d3dAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
31746078-c5c3-4387-a2ed-bd3c8b244c53Product name220250325
037c6bd8-1c81-7b8c-8280-c83d993a1f03Product name220250203
c9eb0343-053f-7f78-730f-1be02ab91c6cProduct name520250130

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
44567-851-01Nicardipine Hydrochloride in Sodium Chloride200 mL in 1 BAGINJECTION, SOLUTION2001
44567-851-12Nicardipine Hydrochloride in Sodium Chloride12 in 1 CARTONINJECTION, SOLUTION121

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
44567-851-01ML - Milliliter44567-85162f03ce1-723f-41c9-a287-af7b39541fd512025-10-14
44567-851-12ML - Milliliter44567-85137eb509b-2b08-4755-93c3-34e5f873eac812025-10-14

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Nicardipine Hydrochloride in Sodium ChlorideNICARDIPINE HYDROCHLORIDEWG Critical Care, LLC9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d2025-06-30Warnings, Adverse reactionsExact identifier
application applno (ANDA): 203978
application number: ANDA203978
ndc (product): 44567-851

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
858599niCARdipine HCl 20 MG in 200 ML InjectionPSN9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d1
858603niCARdipine HCl 40 MG in 200 ML InjectionPSN9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d1
858599200 ML nicardipine hydrochloride 0.1 MG/ML InjectionSCD9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d1
858603200 ML nicardipine hydrochloride 0.2 MG/ML InjectionSCD9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d1
858599nicardipine hydrochloride 20 MG per 200 ML InjectionSY9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d1
858603nicardipine hydrochloride 40 MG per 200 ML InjectionSY9ffe6b6f-b8bc-413f-9bec-7639e9d71d3d1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
44567-851-0144567085101200 mL in 1 BAG200 mlHistorical
44567-851-124456708511212 BAG in 1 CARTON (44567-851-12) / 200 mL in 1 BAG (44567-851-01) 12 bag2025-07-10NoNoCurrent