cyanocobalamin

Product NDC
45802-491
11-digit product format
458020491
Labeler code
45802
Product ID
45802-491_4cf650d9-6d6c-4112-88f2-cd2e94f1f416
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
cyanocobalamin
Dosage form
SPRAY
Route
NASAL
Labeler
Padagis Israel Pharmaceuticals Ltd
Application
ANDA212458
Marketing category
ANDA
Marketing start
2023-12-28
Substance
CYANOCOBALAMIN
Active strength
500 ug/1
Pharmacologic classes
Vitamin B 12 [CS], Vitamin B12 [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A212458-001CYANOCOBALAMINCYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALABRS2020-09-09

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A212458-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALABRS2020-09-09011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALABRS2020-09-0931067a03dcf5…
2025-08-23 18:47 UTC2025-08A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALABRS2020-09-096a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALABRS2020-09-09fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALABRS2020-09-09b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALABRS2020-09-0903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALABRS2020-09-092680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALABRS2020-09-095bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALABRS2020-09-09d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALABRS2020-09-09d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALABRS2020-09-0979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALAB2020-09-09301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALAB2020-09-091e350fbaab3a…
2024-05-31 18:47 UTC2024-05A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALAB2020-09-098072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-095c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-095d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-094b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-09bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-09782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-0987673890dc5c…
2021-03-12 10:30 UTC2021-03A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-095aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-098869cabd3fbd…
2020-11-12 02:37 UTC2020-11A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALAB2020-09-09c0c555d07b60…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALAB2020-09-096a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALAB2020-09-091c564ffb4f44…
2023-12-20 04:57 UTC2023-12A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALAB2020-09-09ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-09a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-099b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-09a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-093f0d92c62455…
2023-05-13 08:27 UTC2023-05A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-09053a50430f4f…
2023-01-26 05:58 UTC2023-01A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-093bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-093a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-09f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-09e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASAL2020-09-09cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A212458-001CYANOCOBALAMIN0.5MG/SPRAYSPRAY, METERED / NASALABRS2020-09-09a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A212458-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A212458-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A212458-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A212458-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A212458-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A212458-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A212458-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A212458-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A212458-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A212458-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A212458-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A212458-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A212458-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A212458-001AB18072bd15b7f6…
2020-11-12 02:37 UTC2020-11A212458-001AB1c0c555d07b60…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A212458-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A212458-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A212458-001AB1ea1830bbd6c7…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A212458-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
cyanocobalamin
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CYANOCOBALAMIN500 ug/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
P6YC3EG204Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
861113Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
971e5f30-55c2-4193-9dd8-b43a1862b92aAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
b82b4008-22fd-05f5-6cc6-c0a6e81c65b8Product name220240805
d206bb34-ea65-399d-70d9-834f22dc2c18Product name320170724

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
45802-491-84cyanocobalamin1 in 1 BOTTLE, UNIT-DOSESPRAY14
45802-491-84cyanocobalamin4 in 1 CARTONSPRAY44

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
45802-491-84EA - Each45802-4915029d2fe-6083-4bd0-b16c-876cf2e3616b12024-01-04

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
45802-491CYANOCOBALAMIN SPRAY [PADAGIS ISRAEL PHARMACEUTICALS LTD]4Current NDC, 2 package rows20240106_971e5f30-55c2-4193-9dd8-b43a1862b92a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
cyanocobalaminCYANOCOBALAMINPadagis Israel Pharmaceuticals Ltd971e5f30-55c2-4193-9dd8-b43a1862b92a2023-02-28Warnings, Adverse reactionsExact identifier
application applno (ANDA): 212458
application number: ANDA212458
ndc (product): 45802-491

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
861113cyanocobalamin 500 MCG/ACTUAT Nasal SprayPSN971e5f30-55c2-4193-9dd8-b43a1862b92a4
861113vitamin B12 0.5 MG/ACTUAT Nasal SpraySCD971e5f30-55c2-4193-9dd8-b43a1862b92a4
861113cyanocobalamin 500 MCG/ACTUAT Nasal SpraySY971e5f30-55c2-4193-9dd8-b43a1862b92a4
861113vitamin B 12 500 MCG/ACTUAT Nasal SpraySY971e5f30-55c2-4193-9dd8-b43a1862b92a4

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
45802-491-84458020491844 BOTTLE, UNIT-DOSE in 1 CARTON (45802-491-84) / 1 SPRAY in 1 BOTTLE, UNIT-DOSE2023-12-28NoNoCurrent