Alosetron Hydrochloride

Product NDC
45963-480
11-digit product format
459630480
Labeler code
45963
Product ID
45963-480_963590cd-862a-cf1d-e053-2a95a90af4c2
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
alosetron hydrochloride
Dosage form
TABLET
Route
ORAL
Labeler
Actavis Pharma, Inc.
Application
NDA021107
Marketing category
NDA
Marketing start
2015-05-26
Marketing end
0000-00-00
Substance
ALOSETRON HYDROCHLORIDE
Active strength
1 mg/1
Pharmacologic classes
Serotonin 3 Receptor Antagonists [MoA],Serotonin-3 Receptor Antagonist [EPC]
NDC exclude flag
No
Listing certified through
2020-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct45963-480DDiscontinued by firm2026-09-09
excluded packagepackage45963-48045963-480-03DDiscontinued by firm2026-09-09

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021107-001LOTRONEXALOSETRON HYDROCHLORIDEEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09
N021107-002LOTRONEXALOSETRON HYDROCHLORIDEEQ 0.5MG BASETABLET / ORALABRLD2003-12-23

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
N021107-001AB
N021107-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09caaa826d4ba7…
2026-08-18 06:07:402026-07N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-2331067a03dcf5…
2025-08-23 18:47 UTC2025-08N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-236a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-2303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-232680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-095bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-235bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09d06236e962d9…
2024-10-29 15:01 UTC2024-10N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-0979d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-2379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-091e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-231e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-098072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-238072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-095c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-235c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-095d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-235d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-094b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-234b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-0974a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-2374a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23bb7c543d1eb4…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N021107-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07N021107-002AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N021107-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021107-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021107-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021107-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N021107-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021107-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021107-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021107-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021107-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021107-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021107-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021107-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021107-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021107-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021107-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021107-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021107-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021107-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021107-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N021107-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021107-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021107-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021107-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021107-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021107-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021107-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021107-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021107-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021107-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021107-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021107-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021107-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021107-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021107-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021107-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021107-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021107-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021107-002AB1bb7c543d1eb4…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
45963-480-03EA - Each45963-480b298407c-d84e-4711-8187-df8cafa6d81e12015-07-20

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
alosetron hydrochlorideACTIVE INGREDIENT2F5R1A46YWALOSETRON HYDROCHLORIDE TABLET [ACTAVIS PHARMA, INC.]4
alosetronACTIVE MOIETY13Z9HTH115ALOSETRON HYDROCHLORIDE TABLET [ACTAVIS PHARMA, INC.]4
cellulose, microcrystallineINACTIVE INGREDIENTOP1R32D61UALOSETRON HYDROCHLORIDE TABLET [ACTAVIS PHARMA, INC.]4
hypromellosesINACTIVE INGREDIENT3NXW29V3WOALOSETRON HYDROCHLORIDE TABLET [ACTAVIS PHARMA, INC.]4
indigotindisulfonate sodiumINACTIVE INGREDIENTD3741U8K7LALOSETRON HYDROCHLORIDE TABLET [ACTAVIS PHARMA, INC.]4
lactoseINACTIVE INGREDIENTJ2B2A4N98GALOSETRON HYDROCHLORIDE TABLET [ACTAVIS PHARMA, INC.]4
magnesium stearateINACTIVE INGREDIENT70097M6I30ALOSETRON HYDROCHLORIDE TABLET [ACTAVIS PHARMA, INC.]4
starch, cornINACTIVE INGREDIENTO8232NY3SJALOSETRON HYDROCHLORIDE TABLET [ACTAVIS PHARMA, INC.]4
titanium dioxideINACTIVE INGREDIENT15FIX9V2JPALOSETRON HYDROCHLORIDE TABLET [ACTAVIS PHARMA, INC.]4
triacetinINACTIVE INGREDIENTXHX3C3X673ALOSETRON HYDROCHLORIDE TABLET [ACTAVIS PHARMA, INC.]4

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
45963-480ALOSETRON HYDROCHLORIDE TABLET [ACTAVIS PHARMA, INC.]11Legacy NDC20241215_969429cb-60b9-4a9c-be60-dd01994431b2.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
LOTRONEXALOSETRON HYDROCHLORIDESebela Pharmaceuticals Inc.35cbb9d5-639b-207a-e054-00144ff88e882026-06-30Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 021107
application number: NDA021107
LOTRONEXALOSETRON HYDROCHLORIDELegacy Pharma USA Inc.c216e967-436f-475a-8e6a-2ad11adc63af2026-03-23Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 021107
application number: NDA021107

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
45963-480-03459630480031 BOTTLE in 1 CARTON (45963-480-03) > 30 TABLET in 1 BOTTLE1 bottle2015-05-260000-00-00NoNoCurrent