CLOBETASOL PROPIONATE

Product NDC
46708-486
Requested package NDC
46708-486-50
11-digit product format
467080486
Labeler code
46708
Product ID
46708-486_39e082e7-ecec-458f-83fe-67edbf4c7bed
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
CLOBETASOL PROPIONATE
Dosage form
SOLUTION
Route
TOPICAL
Labeler
Alembic Pharmaceuticals Limited
Application
ANDA212881
Marketing category
ANDA
Marketing start
2025-03-17
Substance
CLOBETASOL PROPIONATE
Active strength
.5 mg/mL
Pharmacologic classes
Corticosteroid Hormone Receptor Agonists [MoA], Corticosteroid [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A212881-001CLOBETASOL PROPIONATECLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A212881-001AT

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-2131067a03dcf5…
2025-08-23 18:47 UTC2025-08A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-2103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-212680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-215bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-2179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-211e350fbaab3a…
2024-05-31 18:47 UTC2024-05A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-218072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-215c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-215d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-214b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-2174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-2187673890dc5c…
2021-03-12 10:30 UTC2021-03A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-215aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-218869cabd3fbd…
2020-11-12 02:37 UTC2020-11A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21c0c555d07b60…
2019-12-14 00:12 UTC2019-12A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-213f01610625f2…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-216a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-211c564ffb4f44…
2023-12-20 04:57 UTC2023-12A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-219b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-213f0d92c62455…
2023-05-13 08:27 UTC2023-05A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21053a50430f4f…
2023-01-26 05:58 UTC2023-01A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-213bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-213a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A212881-001CLOBETASOL PROPIONATE0.05%SOLUTION / TOPICALAT2019-10-21a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A212881-001AT1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A212881-001AT131067a03dcf5…
2025-08-23 18:47 UTC2025-08A212881-001AT16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A212881-001AT1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A212881-001AT1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A212881-001AT103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A212881-001AT12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A212881-001AT15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A212881-001AT1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A212881-001AT1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A212881-001AT179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A212881-001AT1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A212881-001AT11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A212881-001AT18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A212881-001AT15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A212881-001AT15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A212881-001AT14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A212881-001AT174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A212881-001AT1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A212881-001AT1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A212881-001AT187673890dc5c…
2021-03-12 10:30 UTC2021-03A212881-001AT15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A212881-001AT18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A212881-001AT1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A212881-001AT13f01610625f2…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A212881-001AT16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A212881-001AT11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A212881-001AT1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A212881-001AT1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A212881-001AT19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A212881-001AT1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A212881-001AT13f0d92c62455…
2023-05-13 08:27 UTC2023-05A212881-001AT1053a50430f4f…
2023-01-26 05:58 UTC2023-01A212881-001AT13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A212881-001AT13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A212881-001AT1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A212881-001AT1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A212881-001AT1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A212881-001AT1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
CLOBETASOL PROPIONATE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CLOBETASOL PROPIONATE.5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
779619577MInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
861487Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
46bda1db-c2eb-461a-bcd0-dfdb6c7f542dAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
20abe2c3-3e80-d2b2-39eb-3156e4af4799Product name320250124
45ad92f8-d116-4c0c-851c-2e740b7d8e6fProduct name120250122
42be0ad5-6fd7-4f1b-8108-6d9dd7d571dfProduct name720250107
6c13b22c-b3ba-4127-b768-0132dd5ab0d1Product name120230829
3813b789-94b9-edd6-f010-6b926dd462e5Product name520230113
30eee8a1-850e-41ed-b5ab-761301aeab49Product name620221206
18e5b6f7-c414-b1f1-b684-17fdd02c215eProduct name420210927
1c87bbde-dd91-a122-db33-67ae814cb645Product name720210510
519b5875-7d7d-4aa6-9d3d-470fa1376595Product name420200227
98669154-3e9c-47da-8a2c-656ab71848beProduct name220180607
8d4f8539-436f-453b-8b76-5322d403fc8eProduct name120180131
837ac3c6-ee71-c5a6-6eba-c4065f37e9f5Product name220171010

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
46708-486-25CLOBETASOL PROPIONATE1 in 1 CARTONSOLUTION11
46708-486-25CLOBETASOL PROPIONATE25 mL in 1 BOTTLESOLUTION251
46708-486-50CLOBETASOL PROPIONATE50 mL in 1 BOTTLESOLUTION501
46708-486-50CLOBETASOL PROPIONATE1 in 1 CARTONSOLUTION11

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
46708-486CLOBETASOL PROPIONATE SOLUTION [ALEMBIC PHARMACEUTICALS LIMITED]1Current NDC, 4 package rows20250321_46bda1db-c2eb-461a-bcd0-dfdb6c7f542d.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
CLOBETASOL PROPIONATECLOBETASOL PROPIONATEAlembic Pharmaceuticals Limited46bda1db-c2eb-461a-bcd0-dfdb6c7f542d2025-03-18Adverse reactionsExact identifier
application applno (ANDA): 212881
application number: ANDA212881
ndc (package): 46708-486-50
ndc (product): 46708-486
ndc11 (package): 46708048650
CLOBETASOL PROPIONATECLOBETASOL PROPIONATEAlembic Pharmaceuticals Inc.a75cac17-c0d1-403a-8a63-80b2d43e31692023-12-12Adverse reactionsExact identifier
application applno (ANDA): 212881
application number: ANDA212881

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
861487clobetasol propionate 0.05 % Topical SolutionPSN46bda1db-c2eb-461a-bcd0-dfdb6c7f542d1
861487clobetasol propionate 0.5 MG/ML Topical SolutionSCD46bda1db-c2eb-461a-bcd0-dfdb6c7f542d1
861487clobetasol propionate 0.05 % Topical SolutionSY46bda1db-c2eb-461a-bcd0-dfdb6c7f542d1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
46708-486-50467080486501 BOTTLE in 1 CARTON (46708-486-50) / 50 mL in 1 BOTTLE1 bottle2025-03-17NoNoCurrent