BISOPROLOL FUMARATE

Product NDC
46708-603
11-digit product format
467080603
Labeler code
46708
Product ID
46708-603_ae10b8e1-557d-4437-8a1d-89d7844122c8
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
BISOPROLOL FUMARATE
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Alembic Pharmaceuticals Limited
Application
ANDA204891
Marketing category
ANDA
Marketing start
2019-09-11
Substance
BISOPROLOL FUMARATE
Active strength
5 mg/1
Pharmacologic classes
Adrenergic beta-Antagonists [MoA], beta-Adrenergic Blocker [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A204891-001BISOPROLOL FUMARATEBISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-11
A204891-002BISOPROLOL FUMARATEBISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-11

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A204891-001AB
A204891-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-11011fe1cb6892…
2026-02-19 14:30 UTC2026-02A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-11011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-1131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-1131067a03dcf5…
2025-08-23 18:47 UTC2025-08A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-116a471c1ec25d…
2025-08-23 18:47 UTC2025-08A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-116a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-11fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-11fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-11b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-11b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-1103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-1103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-112680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-112680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-115bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-115bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-11d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-11d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-11d06236e962d9…
2024-10-29 15:01 UTC2024-10A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-11d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-1179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-1179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-11301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-11301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-111e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-111e350fbaab3a…
2024-05-31 18:47 UTC2024-05A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-118072bd15b7f6…
2024-05-31 18:47 UTC2024-05A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-118072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-115c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-115c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-115d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-115d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-114b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-114b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-1174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-1174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-11bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-11bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A204891-001BISOPROLOL FUMARATE5MGTABLET / ORALAB2017-01-11782e0a99824c…
2021-12-28 21:50 UTC2021-12A204891-002BISOPROLOL FUMARATE10MGTABLET / ORALAB2017-01-11782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A204891-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A204891-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A204891-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A204891-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A204891-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A204891-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A204891-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A204891-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A204891-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A204891-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A204891-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A204891-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A204891-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A204891-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A204891-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A204891-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A204891-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A204891-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A204891-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A204891-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A204891-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A204891-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A204891-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A204891-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A204891-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A204891-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A204891-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A204891-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A204891-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A204891-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A204891-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A204891-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A204891-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A204891-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A204891-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A204891-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A204891-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A204891-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A204891-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12A204891-002AB1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
BISOPROLOL FUMARATE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BISOPROLOL FUMARATE5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
UR59KN573LInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
854901Internal RxNorm lookup
854905Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ae10b8e1-557d-4437-8a1d-89d7844122c8Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
97e4a60d-917d-ef62-dc8a-bd557b62b708Product name720260129
9b303cd4-3186-2454-5706-3137e8b2dfd2Product name420221110

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
46708-603-30BISOPROLOL FUMARATE30 in 1 BOTTLE, PLASTICTABLET, FILM COATED301
46708-603-31BISOPROLOL FUMARATE100 in 1 BOTTLE, PLASTICTABLET, FILM COATED1001
46708-603-71BISOPROLOL FUMARATE500 in 1 BOTTLE, PLASTICTABLET, FILM COATED5001

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
46708-603BISOPROLOL FUMARATE TABLET, FILM COATED [ALEMBIC PHARMACEUTICALS LIMITED]1Current NDC, 3 package rows20230208_ae10b8e1-557d-4437-8a1d-89d7844122c8.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
BISOPROLOL FUMARATEBISOPROLOL FUMARATEAlembic Pharmaceuticals Limitedae10b8e1-557d-4437-8a1d-89d7844122c82023-02-07Warnings, Adverse reactionsExact identifier
application applno (ANDA): 204891
application number: ANDA204891
ndc (product): 46708-603
BISOPROLOL FUMARATEBISOPROLOL FUMARATEAlembic Pharmaceuticals Inc.9b2eb4ea-001e-436c-93ba-20a7f5bc5f042021-10-08Warnings, Adverse reactionsExact identifier
application applno (ANDA): 204891
application number: ANDA204891

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
854901bisoprolol fumarate 10 MG Oral TabletPSNae10b8e1-557d-4437-8a1d-89d7844122c81
854905bisoprolol fumarate 5 MG Oral TabletPSNae10b8e1-557d-4437-8a1d-89d7844122c81
854901bisoprolol fumarate 10 MG Oral TabletSCDae10b8e1-557d-4437-8a1d-89d7844122c81
854905bisoprolol fumarate 5 MG Oral TabletSCDae10b8e1-557d-4437-8a1d-89d7844122c81

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
46708-603-304670806033030 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (46708-603-30) 2019-09-11NoNoCurrent
46708-603-3146708060331100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (46708-603-31) 2021-03-25NoNoCurrent
46708-603-7146708060371500 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (46708-603-71) 2019-09-11NoNoCurrent