Home NDC 47426-201 CINVANTI
Product NDC 47426-201
11-digit product format 474260201
Labeler code 47426
Product ID 47426-201_94c147fd-c8bd-428c-911b-f1aba4ab8729
Type HUMAN PRESCRIPTION DRUG
Nonproprietary name aprepitant
Dosage form INJECTION, EMULSION
Route INTRAVENOUS
Labeler Heron Therapeutics, Inc.
Application NDA209296
Marketing category NDA
Marketing start 2018-01-03
Substance APREPITANT
Active strength 130 mg/18mL
Pharmacologic classes Cytochrome P450 2C9 Inducers [MoA], Cytochrome P450 3A4 Inducers [MoA], Cytochrome P450 3A4 Inhibitors [MoA], Neurokinin 1 Antagonists [MoA], Substance P/Neurokinin-1 Receptor Antagonist [EPC]
NDC exclude flag No
Listing certified through 2027-12-31
Current FDA listing Yes Source provenance: Browse the complete Orange Book source catalog · source snapshot 42 .
Orange Book products# Current product rows page 1 of 1 · 1 matching rows.
Application-product, Trade name, Ingredient table Application-product Trade name Ingredient Strength Dosage form / route TE codes RLD / RS Approval date N209296-001 CINVANTI APREPITANT 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09
Orange Book patents# Current patent rows page 1 of 1 · 13 matching rows.
Application-product, Patent, Expiration table Application-product Patent Expiration Use code Coverage / status Submission date N209296-001 10500208 2035-09-18 Drug product 2019-12-23 N209296-001 10624850 2035-09-18 U-2161 2020-04-30 N209296-001 10953018 2035-09-18 U-2161 2021-04-08 N209296-001 11173118 2035-09-18 Drug product 2021-12-13 N209296-001 11744800 2035-09-18 Drug product 2023-10-02 N209296-001 12115254 2035-09-18 Drug product 2024-11-07 N209296-001 12115255 2035-09-18 Drug product 2024-11-07 N209296-001 12290520 2035-09-18 Drug product 2025-05-12 N209296-001 9561229 2035-09-18 U-2161 Drug product 2017-12-05 N209296-001 9808465 2035-09-18 U-2161 2017-12-05 N209296-001 9974742 2035-09-18 Drug product 2018-06-19 N209296-001 9974793 2035-09-18 Drug product 2018-06-19 N209296-001 9974794 2035-09-18 U-2161 Drug product 2018-06-19
Observed Orange Book product history# Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
Product history page 1 of 2 · 42 observed states.
Captured, Edition, Application-product table Captured Edition Application-product Trade name Strength Dosage form / route Product TE source text RLD / RS Approval date Source SHA-256 2026-08-18 06:07:40 2026-07 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 caaa826d4ba7…2026-02-19 14:30 UTC 2026-02 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 6a471c1ec25d…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 fd3edfee7708…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 b8a1b40f171c…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 03ed91905a0d…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 2680178bc6a6…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 5bbf6a4d5a75…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 d8e5a09893c0…2024-10-29 15:01 UTC 2024-10 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 d06236e962d9…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 79d66fd596c7…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 301d65b070ca…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 1e350fbaab3a…2024-05-31 18:47 UTC 2024-05 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 8072bd15b7f6…2022-06-29 02:47 UTC · 2 captures of this ZIP 2022-06 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 5c6f7cd8ea54…2022-04-08 23:34 UTC 2022-04 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 5d02ea3f76ae…2022-04-04 05:41 UTC 2022-04 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 4b0b4de00fa7…2019-12-13 00:20 UTC 2019-12 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 74a2ff9319b5…2022-03-09 01:35 UTC 2022-03 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 bb7c543d1eb4…2021-12-28 21:50 UTC 2021-12 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 782e0a99824c…2021-05-05 16:15 UTC · 3 captures of this ZIP 2021-05 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 87673890dc5c…2021-03-12 10:30 UTC 2021-03 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 5aa47cf7b7d7…2020-12-22 03:56 UTC 2020-12 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 8869cabd3fbd…2020-11-12 02:37 UTC 2020-11 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 c0c555d07b60…2019-12-14 00:12 UTC 2019-12 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 3f01610625f2…2019-09-15 20:21 UTC 2019-09 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 b00525d2431f…2019-07-19 19:46 UTC 2019-07 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 ea99ee380514…2024-03-16 18:09 UTC · 4 captures of this ZIP 2024-03 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 6a51e52b5d6a…2024-02-18 07:12 UTC 2024-02 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 1c564ffb4f44…2023-12-20 04:57 UTC 2023-12 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 ea1830bbd6c7…2023-11-28 05:40 UTC · 2 captures of this ZIP 2023-11 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 a72a2bbeb626…2023-10-25 00:34 UTC · 2 captures of this ZIP 2023-10 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 9b2671bbb829…2023-07-15 15:27 UTC · 2 captures of this ZIP 2023-07 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 a67488948f0b…2023-06-13 01:57 UTC · 3 captures of this ZIP 2023-06 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 3f0d92c62455…2023-05-13 08:27 UTC 2023-05 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 053a50430f4f…2023-01-26 05:58 UTC 2023-01 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 3bdfa0b2c4d7…2022-11-12 20:34 UTC · 5 captures of this ZIP 2022-11 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 3a93d1ddd44b…2022-10-28 04:53 UTC 2022-10 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 f41ea6bd6efb…2022-09-29 23:25 UTC 2022-09 N209296-001 CINVANTI 130MG/18ML (7.2MG/ML) EMULSION / INTRAVENOUS RLD, RS 2017-11-09 e64feba35796…
Observed Orange Book patent history# Patent history page 1 of 10 · 397 observed states.
Captured, Edition, Application-product table Captured Edition Application-product Patent Expiration Use code Coverage / status Submission date Source SHA-256 2026-08-18 06:07:40 2026-07 N209296-001 10500208 2035-09-18 Drug product 2019-12-23 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N209296-001 10624850 2035-09-18 U-2161 2020-04-30 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N209296-001 10953018 2035-09-18 U-2161 2021-04-08 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N209296-001 11173118 2035-09-18 Drug product 2021-12-13 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N209296-001 11744800 2035-09-18 Drug product 2023-10-02 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N209296-001 12115254 2035-09-18 Drug product 2024-11-07 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N209296-001 12115255 2035-09-18 Drug product 2024-11-07 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N209296-001 12290520 2035-09-18 Drug product 2025-05-12 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N209296-001 9561229 2035-09-18 U-2161 Drug product 2017-12-05 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N209296-001 9808465 2035-09-18 U-2161 2017-12-05 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N209296-001 9974742 2035-09-18 Drug product 2018-06-19 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N209296-001 9974793 2035-09-18 Drug product 2018-06-19 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N209296-001 9974794 2035-09-18 U-2161 Drug product 2018-06-19 caaa826d4ba7…2026-02-19 14:30 UTC 2026-02 N209296-001 10500208 2035-09-18 Drug product 2019-12-23 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N209296-001 10624850 2035-09-18 U-2161 2020-04-30 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N209296-001 10953018 2035-09-18 U-2161 2021-04-08 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N209296-001 11173118 2035-09-18 Drug product 2021-12-13 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N209296-001 11744800 2035-09-18 Drug product 2023-10-02 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N209296-001 12115254 2035-09-18 Drug product 2024-11-07 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N209296-001 12115255 2035-09-18 Drug product 2024-11-07 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N209296-001 12290520 2035-09-18 Drug product 2025-05-12 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N209296-001 9561229 2035-09-18 U-2161 Drug product 2017-12-05 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N209296-001 9808465 2035-09-18 U-2161 2017-12-05 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N209296-001 9974742 2035-09-18 Drug product 2018-06-19 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N209296-001 9974793 2035-09-18 Drug product 2018-06-19 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N209296-001 9974794 2035-09-18 U-2161 Drug product 2018-06-19 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N209296-001 10500208 2035-09-18 Drug product 2019-12-23 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N209296-001 10624850 2035-09-18 U-2161 2020-04-30 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N209296-001 10953018 2035-09-18 U-2161 2021-04-08 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N209296-001 11173118 2035-09-18 Drug product 2021-12-13 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N209296-001 11744800 2035-09-18 Drug product 2023-10-02 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N209296-001 12115254 2035-09-18 Drug product 2024-11-07 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N209296-001 12115255 2035-09-18 Drug product 2024-11-07 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N209296-001 12290520 2035-09-18 Drug product 2025-05-12 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N209296-001 9561229 2035-09-18 U-2161 Drug product 2017-12-05 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N209296-001 9808465 2035-09-18 U-2161 2017-12-05 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N209296-001 9974742 2035-09-18 Drug product 2018-06-19 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N209296-001 9974793 2035-09-18 Drug product 2018-06-19 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N209296-001 9974794 2035-09-18 U-2161 Drug product 2018-06-19 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 N209296-001 10500208 2035-09-18 Drug product 2019-12-23 6a471c1ec25d…
Additional Listing Data#
Finished product Yes
Brand name base CINVANTI
Listing expiration 2027-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength APREPITANT 130 mg/18mL
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 1NF15YR6UY Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 2 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 1995150 Internal RxNorm lookup 1995155 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Product Concepts# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 47426-201-01 CINVANTI 1 in 1 CARTON INJECTION, EMULSION 1 15 47426-201-01 CINVANTI 18 mL in 1 VIAL, GLASS INJECTION, EMULSION 18 15
DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 47426-201 CINVANTI (APREPITANT) INJECTION, EMULSION [HERON THERAPEUTICS, INC.] 12 Current NDC, Legacy NDC, 2 package rows 20240319_4c218d3a-a508-4abc-9ed8-a6e8e191d1b4.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 1 of 1 · 1 matching rows.
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Marketing start Marketing end Sample Exclude flag Status 47426-201-01 47426020101 1 VIAL, GLASS in 1 CARTON (47426-201-01) / 18 mL in 1 VIAL, GLASS 2018-01-03 0000-00-00 No No Current