Nitrous Oxide

Product NDC: 49972-004
11-digit product format: 499720004
Labeler code: 49972
Product ID: 49972-004_845551da-0662-4741-bb99-2b834f8c97f3
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: Nitrous Oxide
Dosage form: GAS
Route: RESPIRATORY (INHALATION)
Labeler: Praxair Distribution Southeast LLC
Marketing category: UNAPPROVED MEDICAL GAS
Marketing start: 2007-10-01
Marketing end: 0000-00-00
Substance: NITROUS OXIDE
Active strength: 990 mL/L
NDC exclude flag: E
Listing certified through: 2017-12-31
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 21 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded product	product	49972-004		I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-01	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-02	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-03	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-04	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-05	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-06	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-07	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-08	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-09	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-10	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-11	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-12	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-13	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-14	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-15	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-16	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-17	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-18	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-19	I	Inactivated by FDA	2026-10-05
excluded package	package	49972-004	49972-004-20	I	Inactivated by FDA	2026-10-05

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 8 · 462 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-10	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-03	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-02	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-13	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-12	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-06	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-04	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-14	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-16	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-18	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-20	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-15	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-17	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-01	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-19	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-09	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-07	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-05	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-08	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49972-004-11	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-10	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-03	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-02	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-13	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-12	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-06	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-04	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-14	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-16	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-18	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-20	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-15	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-17	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-01	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-19	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-09	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-07	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-05	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-08	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49972-004-11	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-10	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-03	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-02	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-13	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-12	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-06	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-04	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-14	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-16	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-18	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-20	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-15	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-17	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-01	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-19	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-09	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49972-004-07	`2ef7874e63bc…`	`57b86245f4fa…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

FDA-Initiated Inactive NDC Indexing#

NDC, Related label table
NDC	Related label
49972-004-01	Nitrous Oxide
49972-004-02	Nitrous Oxide
49972-004-03	Nitrous Oxide
49972-004-04	Nitrous Oxide
49972-004-05	Nitrous Oxide
49972-004-06	Nitrous Oxide
49972-004-07	Nitrous Oxide
49972-004-08	Nitrous Oxide
49972-004-09	Nitrous Oxide
49972-004-10	Nitrous Oxide
49972-004-11	Nitrous Oxide
49972-004-12	Nitrous Oxide
49972-004-13	Nitrous Oxide
49972-004-14	Nitrous Oxide
49972-004-15	Nitrous Oxide
49972-004-16	Nitrous Oxide
49972-004-17	Nitrous Oxide
49972-004-18	Nitrous Oxide
49972-004-19	Nitrous Oxide
49972-004-20	Nitrous Oxide

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
49972-004-01	Nitrous Oxide	17987 L in 1 CYLINDER	GAS	17987	1
49972-004-02	Nitrous Oxide	15770 L in 1 CYLINDER	GAS	15770	1
49972-004-03	Nitrous Oxide	14784 L in 1 CYLINDER	GAS	14784	1
49972-004-04	Nitrous Oxide	9610 L in 1 CYLINDER	GAS	9610	1
49972-004-05	Nitrous Oxide	7885 L in 1 CYLINDER	GAS	7885	1
49972-004-06	Nitrous Oxide	4928 L in 1 CYLINDER	GAS	4928	1
49972-004-07	Nitrous Oxide	2664 L in 1 CYLINDER	GAS	2664	1
49972-004-08	Nitrous Oxide	1725 L in 1 CYLINDER	GAS	1725	1
49972-004-09	Nitrous Oxide	1232 L in 1 CYLINDER	GAS	1232	1
49972-004-10	Nitrous Oxide	986 L in 1 CYLINDER	GAS	986	1
49972-004-11	Nitrous Oxide	493 L in 1 CYLINDER	GAS	493	1
49972-004-12	Nitrous Oxide	246 L in 1 CYLINDER	GAS	246	1
49972-004-13	Nitrous Oxide	17248 L in 1 DEWAR	GAS	17248	1
49972-004-14	Nitrous Oxide	1971 L in 1 DEWAR	GAS	1971	1
49972-004-15	Nitrous Oxide	46816 L in 1 DEWAR	GAS	46816	1
49972-004-16	Nitrous Oxide	88458 L in 1 DEWAR	GAS	88458	1
49972-004-17	Nitrous Oxide	93632 L in 1 DEWAR	GAS	93632	1
49972-004-18	Nitrous Oxide	107667 L in 1 DEWAR	GAS	107667	1
49972-004-19	Nitrous Oxide	130099 L in 1 DEWAR	GAS	130099	1
49972-004-20	Nitrous Oxide	141680 L in 1 DEWAR	GAS	141680	1

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version	Uploaded
Nitrous Oxide	ACTIVE INGREDIENT	K50XQU1029	NITROUS OXIDE GAS [PRAXAIR DISTRIBUTION SOUTHEAST LLC]	1
Nitrous Oxide	ACTIVE MOIETY	K50XQU1029	NITROUS OXIDE GAS [PRAXAIR DISTRIBUTION SOUTHEAST LLC]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
49972-004	NITROUS OXIDE GAS [PRAXAIR DISTRIBUTION SOUTHEAST LLC]	1	Legacy NDC, 20 package rows	20121204_97e629a0-34b8-4a01-9a42-7ded32e3f260.zip

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
K50XQU1029	NITROUS OXIDE	10024-97-2	NITROUS OXIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
312022	nitrous oxide 99 % Gas for Inhalation	PSN	97e629a0-34b8-4a01-9a42-7ded32e3f260	1
312022	nitrous oxide 99 % Gas for Inhalation	SCD	97e629a0-34b8-4a01-9a42-7ded32e3f260	1

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Status
49972-004-01	49972000401	17987 L in 1 CYLINDER	17987 l	Historical
49972-004-02	49972000402	15770 L in 1 CYLINDER	15770 l	Historical
49972-004-03	49972000403	14784 L in 1 CYLINDER	14784 l	Historical
49972-004-04	49972000404	9610 L in 1 CYLINDER	9610 l	Historical
49972-004-05	49972000405	7885 L in 1 CYLINDER	7885 l	Historical
49972-004-06	49972000406	4928 L in 1 CYLINDER	4928 l	Historical
49972-004-07	49972000407	2664 L in 1 CYLINDER	2664 l	Historical
49972-004-08	49972000408	1725 L in 1 CYLINDER	1725 l	Historical
49972-004-09	49972000409	1232 L in 1 CYLINDER	1232 l	Historical
49972-004-10	49972000410	986 L in 1 CYLINDER	986 l	Historical
49972-004-11	49972000411	493 L in 1 CYLINDER	493 l	Historical
49972-004-12	49972000412	246 L in 1 CYLINDER	246 l	Historical
49972-004-13	49972000413	17248 L in 1 DEWAR	17248 l	Historical
49972-004-14	49972000414	1971 L in 1 DEWAR	1971 l	Historical
49972-004-15	49972000415	46816 L in 1 DEWAR	46816 l	Historical
49972-004-16	49972000416	88458 L in 1 DEWAR	88458 l	Historical
49972-004-17	49972000417	93632 L in 1 DEWAR	93632 l	Historical
49972-004-18	49972000418	107667 L in 1 DEWAR	107667 l	Historical
49972-004-19	49972000419	130099 L in 1 DEWAR	130099 l	Historical
49972-004-20	49972000420	141680 L in 1 DEWAR	141680 l	Historical