Premarin

Product NDC
50090-0167
11-digit product format
500900167
Labeler code
50090
Product ID
50090-0167_3438144a-8319-4971-981b-38f13201b980
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
estrogens, conjugated
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
A-S Medication Solutions
Application
NDA004782
Marketing category
NDA
Marketing start
2006-01-01
Substance
ESTROGENS, CONJUGATED
Active strength
.625 mg/1
Pharmacologic classes
Estrogen Receptor Agonists [MoA], Estrogen [EPC], Estrogens, Conjugated (USP) [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 6 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N004782-001PREMARINESTROGENS, CONJUGATED1.25MGTABLET / ORALABRLD, RS, Approved before 1982
N004782-002PREMARINESTROGENS, CONJUGATED2.5MGTABLET / ORALApproved before 1982
N004782-003PREMARINESTROGENS, CONJUGATED0.3MGTABLET / ORALABRLD, Approved before 1982
N004782-004PREMARINESTROGENS, CONJUGATED0.625MGTABLET / ORALABRLD, RS, Approved before 1982
N004782-005PREMARINESTROGENS, CONJUGATED0.9MGTABLET / ORALABRLD, RS1984-01-26
N004782-006PREMARINESTROGENS, CONJUGATED0.45MGTABLET / ORALABRLD2003-07-16

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 5 matching rows.

Application-product, TE code table
Application-productTE code
N004782-001AB
N004782-003AB
N004782-004AB
N004782-005AB
N004782-006AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 7 · 246 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N004782-001PREMARIN1.25MGTABLET / ORALABRLD, RS, Approved before 1982011fe1cb6892…
2026-02-19 14:30 UTC2026-02N004782-002PREMARIN2.5MGTABLET / ORALApproved before 1982011fe1cb6892…
2026-02-19 14:30 UTC2026-02N004782-003PREMARIN0.3MGTABLET / ORALABRLD, Approved before 1982011fe1cb6892…
2026-02-19 14:30 UTC2026-02N004782-004PREMARIN0.625MGTABLET / ORALABRLD, RS, Approved before 1982011fe1cb6892…
2026-02-19 14:30 UTC2026-02N004782-005PREMARIN0.9MGTABLET / ORALABRLD, RS1984-01-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02N004782-006PREMARIN0.45MGTABLET / ORALABRLD2003-07-16011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N004782-001PREMARIN1.25MGTABLET / ORALABRLD, RS, Approved before 198231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N004782-002PREMARIN2.5MGTABLET / ORALApproved before 198231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N004782-003PREMARIN0.3MGTABLET / ORALABRLD, Approved before 198231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N004782-004PREMARIN0.625MGTABLET / ORALABRLD, RS, Approved before 198231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N004782-005PREMARIN0.9MGTABLET / ORALABRLD, RS1984-01-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N004782-006PREMARIN0.45MGTABLET / ORALABRLD2003-07-1631067a03dcf5…
2025-08-23 18:47 UTC2025-08N004782-001PREMARIN1.25MGTABLET / ORALRLD, RS, Approved before 19826a471c1ec25d…
2025-08-23 18:47 UTC2025-08N004782-002PREMARIN2.5MGTABLET / ORALApproved before 19826a471c1ec25d…
2025-08-23 18:47 UTC2025-08N004782-003PREMARIN0.3MGTABLET / ORALRLD, Approved before 19826a471c1ec25d…
2025-08-23 18:47 UTC2025-08N004782-004PREMARIN0.625MGTABLET / ORALRLD, RS, Approved before 19826a471c1ec25d…
2025-08-23 18:47 UTC2025-08N004782-005PREMARIN0.9MGTABLET / ORALRLD, RS1984-01-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08N004782-006PREMARIN0.45MGTABLET / ORALRLD2003-07-166a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N004782-001PREMARIN1.25MGTABLET / ORALRLD, RS, Approved before 1982fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N004782-002PREMARIN2.5MGTABLET / ORALApproved before 1982fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N004782-003PREMARIN0.3MGTABLET / ORALRLD, Approved before 1982fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N004782-004PREMARIN0.625MGTABLET / ORALRLD, RS, Approved before 1982fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N004782-005PREMARIN0.9MGTABLET / ORALRLD, RS1984-01-26fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N004782-006PREMARIN0.45MGTABLET / ORALRLD2003-07-16fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N004782-001PREMARIN1.25MGTABLET / ORALRLD, RS, Approved before 1982b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N004782-002PREMARIN2.5MGTABLET / ORALApproved before 1982b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N004782-003PREMARIN0.3MGTABLET / ORALRLD, Approved before 1982b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N004782-004PREMARIN0.625MGTABLET / ORALRLD, RS, Approved before 1982b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N004782-005PREMARIN0.9MGTABLET / ORALRLD, RS1984-01-26b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N004782-006PREMARIN0.45MGTABLET / ORALRLD2003-07-16b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N004782-001PREMARIN1.25MGTABLET / ORALRLD, RS, Approved before 198203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N004782-002PREMARIN2.5MGTABLET / ORALApproved before 198203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N004782-003PREMARIN0.3MGTABLET / ORALRLD, Approved before 198203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N004782-004PREMARIN0.625MGTABLET / ORALRLD, RS, Approved before 198203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N004782-005PREMARIN0.9MGTABLET / ORALRLD, RS1984-01-2603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N004782-006PREMARIN0.45MGTABLET / ORALRLD2003-07-1603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N004782-001PREMARIN1.25MGTABLET / ORALRLD, RS, Approved before 19822680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N004782-002PREMARIN2.5MGTABLET / ORALApproved before 19822680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N004782-003PREMARIN0.3MGTABLET / ORALRLD, Approved before 19822680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N004782-004PREMARIN0.625MGTABLET / ORALRLD, RS, Approved before 19822680178bc6a6…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N004782-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N004782-003AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N004782-004AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N004782-005AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N004782-006AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N004782-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N004782-003AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N004782-004AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N004782-005AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N004782-006AB131067a03dcf5…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N004782-001AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N004782-003AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N004782-004AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N004782-005AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N004782-006AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Premarin
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ESTROGENS, CONJUGATED.625 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
IU5QR144QXInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
150840Internal RxNorm lookup
310197Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
a3b86b85-8923-42ae-aa31-a66a6e090327Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
d95be220-b30e-4165-a12d-f83825b0efb1Product name120160111
882e78d5-69f7-4a43-812f-1c1628241bbcProduct name120150910
2e1ce74f-4938-37b4-e2b4-cfd7971b45eaProduct name120140508
d90784c3-64a2-2f23-9acd-d948d25bf235Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
50090-0167-0Premarin100 in 1 BOTTLETABLET, FILM COATED10023
50090-0167-5Premarin30 in 1 BOTTLETABLET, FILM COATED3023

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
50090-0167-5EA - Each50090-0167ccf2f471-e9cb-4da3-af85-3ee0ebbe0c7612018-08-13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
50090-0167PREMARIN (ESTROGENS, CONJUGATED) TABLET, FILM COATED [A-S MEDICATION SOLUTIONS]23Current NDC, Legacy NDC, 2 package rows20250406_a3b86b85-8923-42ae-aa31-a66a6e090327.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
PremarinESTROGENS, CONJUGATEDWyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.258e1602-a3cf-4ccc-ca80-73dbbfb812ff2026-06-04Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 004782
application number: NDA004782
Conjugated EstrogensESTROGENS, CONJUGATEDPrasco Laboratoriesce793f9e-0c20-43e6-9dc0-064e5c82e2432026-02-27Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 004782
application number: NDA004782
PremarinESTROGENS, CONJUGATEDA-S Medication Solutionsa3b86b85-8923-42ae-aa31-a66a6e0903272025-04-02Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 004782
application number: NDA004782
ndc (product): 50090-0167
PREMARINESTROGENS, CONJUGATEDA-S Medication Solutions2b4dbb7c-4e6d-47c9-b940-fef91f1f4a052024-02-04Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 004782
application number: NDA004782

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
310197estrogens, conjugated 0.625 MG Oral TabletPSNa3b86b85-8923-42ae-aa31-a66a6e09032723
150840PREMARIN 0.625 MG Oral TabletPSNa3b86b85-8923-42ae-aa31-a66a6e09032723
150840estrogens, conjugated (USP) 0.625 MG Oral Tablet [Premarin]SBDa3b86b85-8923-42ae-aa31-a66a6e09032723
310197estrogens, conjugated (USP) 0.625 MG Oral TabletSCDa3b86b85-8923-42ae-aa31-a66a6e09032723
310197estrogens, conjugated (USP) 625 MCG Oral TabletSYa3b86b85-8923-42ae-aa31-a66a6e09032723
150840Premarin 0.625 MG Oral TabletSYa3b86b85-8923-42ae-aa31-a66a6e09032723

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
50090-0167-050090016700100 TABLET, FILM COATED in 1 BOTTLE (50090-0167-0) 2018-10-290000-00-00NoNoCurrent
50090-0167-55009001670530 TABLET, FILM COATED in 1 BOTTLE (50090-0167-5) 2016-06-210000-00-00NoNoCurrent