Metoprolol tartrate

Product NDC: 50090-0489
11-digit product format: 500900489
Labeler code: 50090
Product ID: 50090-0489_158c80c3-3d37-4e99-bfd0-83aa559d15c0
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: Metoprolol tartrate
Dosage form: TABLET
Route: ORAL
Labeler: A-S Medication Solutions
Application: ANDA074644
Marketing category: ANDA
Marketing start: 2015-06-29
Marketing end: 0000-00-00
Substance: METOPROLOL TARTRATE
Active strength: 100 mg/1
Pharmacologic classes: Adrenergic beta-Antagonists [MoA],beta-Adrenergic Blocker [EPC]
NDC exclude flag: No
Listing certified through: 2022-12-31
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 5 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded product	product	50090-0489		D	Discontinued by firm	2026-08-17
excluded package	package	50090-0489	50090-0489-0	D	Discontinued by firm	2026-08-17
excluded package	package	50090-0489	50090-0489-1	D	Discontinued by firm	2026-08-17
excluded package	package	50090-0489	50090-0489-3	D	Discontinued by firm	2026-08-17
excluded package	package	50090-0489	50090-0489-4	D	Discontinued by firm	2026-08-17

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 10 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	50090-0489-3	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	50090-0489-0	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	50090-0489-1	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	50090-0489-4	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	50090-0489-3	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	50090-0489-0	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	50090-0489-1	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	50090-0489-4	`f5e01cc5f278…`	`a2eaf40c39c3…`

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
A074644-001	METOPROLOL TARTRATE	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB		1996-12-10
A074644-002	METOPROLOL TARTRATE	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB		1996-12-10

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-product	TE code
A074644-001	AB
A074644-002	AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	Approval date	Source SHA-256
2026-08-18 06:07:40	2026-07	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	A074644-001	METOPROLOL TARTRATE	50MG	TABLET / ORAL	AB	1996-12-10	`bb7c543d1eb4…`
2022-03-09 01:35 UTC	2022-03	A074644-002	METOPROLOL TARTRATE	100MG	TABLET / ORAL	AB	1996-12-10	`bb7c543d1eb4…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-08-18 06:07:40	2026-07	A074644-001	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A074644-002	AB	1	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A074644-001	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A074644-002	AB	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A074644-001	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A074644-002	AB	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A074644-001	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A074644-002	AB	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A074644-001	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A074644-002	AB	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A074644-001	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A074644-002	AB	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A074644-001	AB	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A074644-002	AB	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A074644-001	AB	1	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A074644-002	AB	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A074644-001	AB	1	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A074644-002	AB	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A074644-001	AB	1	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A074644-002	AB	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A074644-001	AB	1	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A074644-002	AB	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A074644-001	AB	1	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A074644-002	AB	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A074644-001	AB	1	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A074644-002	AB	1	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A074644-001	AB	1	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A074644-002	AB	1	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	A074644-001	AB	1	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	A074644-002	AB	1	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A074644-001	AB	1	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A074644-002	AB	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	A074644-001	AB	1	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	A074644-002	AB	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	A074644-001	AB	1	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	A074644-002	AB	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	A074644-001	AB	1	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	A074644-002	AB	1	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	A074644-001	AB	1	`bb7c543d1eb4…`
2022-03-09 01:35 UTC	2022-03	A074644-002	AB	1	`bb7c543d1eb4…`

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Related label table
NDC	Effective	Related label
50090-0489-0	2023-02-06	Metoprolol Tartrate Tablets, USP Rx only
50090-0489-1	2023-02-06	Metoprolol Tartrate Tablets, USP Rx only
50090-0489-3	2023-02-06	Metoprolol Tartrate Tablets, USP Rx only
50090-0489-4	2023-02-06	Metoprolol Tartrate Tablets, USP Rx only
50090-0489-0	2023-01-30	Metoprolol Tartrate Tablets, USP Rx only
50090-0489-1	2023-01-30	Metoprolol Tartrate Tablets, USP Rx only
50090-0489-3	2023-01-30	Metoprolol Tartrate Tablets, USP Rx only
50090-0489-4	2023-01-30	Metoprolol Tartrate Tablets, USP Rx only

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
50090-0489-0	EA - Each	50090-0489	b78cee35-f129-4751-99dc-1feca8c458d9	1	2018-09-05
50090-0489-1	EA - Each	50090-0489	239e605f-048e-49da-881c-fa563cbf227a	1	2018-09-05
50090-0489-3	EA - Each	50090-0489	5cd1c87c-ffe6-4568-bb70-83234a71d554	1	2018-09-05
50090-0489-4	EA - Each	50090-0489	08b5c47c-04be-43de-a838-4f738445cc44	1	2018-09-05

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
W5S57Y3A5L	METOPROLOL TARTRATE	56392-17-7	METOPROLOL TARTRATE

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
50090-0489-0	50090048900	30 TABLET in 1 BOTTLE (50090-0489-0)	30 tablet	2015-06-29	0000-00-00	No	No	Current
50090-0489-1	50090048901	60 TABLET in 1 BOTTLE (50090-0489-1)	60 tablet	2016-06-29	0000-00-00	No	No	Current
50090-0489-3	50090048903	90 TABLET in 1 BOTTLE (50090-0489-3)	90 tablet	2016-06-29	0000-00-00	No	No	Current
50090-0489-4	50090048904	180 TABLET in 1 BOTTLE (50090-0489-4)	180 tablet	2015-06-29	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Metoprolol Tartrate Tablets, USP Rx only	A-S Medication Solutions	2023-09-06	HUMAN PRESCRIPTION DRUG LABEL	19