Naloxone Hydrochloride

Product NDC
50090-1836
Requested package NDC
50090-1836-0
11-digit product format
500901836
Labeler code
50090
Product ID
50090-1836_9ad14755-0dc9-472b-b478-12e83b874124
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
NALOXONE HYDROCHLORIDE
Dosage form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS
Labeler
A-S Medication Solutions
Application
ANDA070256
Marketing category
ANDA
Marketing start
2005-07-12
Marketing end
0000-00-00
Substance
NALOXONE HYDROCHLORIDE
Active strength
0 mg/mL
Pharmacologic classes
Opioid Antagonist [EPC],Opioid Antagonists [MoA]
NDC exclude flag
No
Listing certified through
2020-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded packagepackage50090-183650090-1836-0DDiscontinued by firm2026-08-11

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 12 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Snapshot, Source SHA-256 table
Captured / source dateSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-312ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-100efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A070256-001NALOXONE HYDROCHLORIDENALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A070256-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-0731067a03dcf5…
2025-08-23 18:47 UTC2025-08A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-076a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-0703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-072680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-075bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-0779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-071e350fbaab3a…
2024-05-31 18:47 UTC2024-05A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-078072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-075c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-075d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-074b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-0774a2ff9319b5…
2022-03-09 01:35 UTC2022-03A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-0787673890dc5c…
2021-03-12 10:30 UTC2021-03A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-075aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-078869cabd3fbd…
2020-11-12 02:37 UTC2020-11A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07c0c555d07b60…
2019-12-14 00:12 UTC2019-12A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-073f01610625f2…
2019-09-15 20:21 UTC2019-09A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07b00525d2431f…
2019-07-19 19:46 UTC2019-07A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-076a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-071c564ffb4f44…
2023-12-20 04:57 UTC2023-12A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-079b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-073f0d92c62455…
2023-05-13 08:27 UTC2023-05A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07053a50430f4f…
2023-01-26 05:58 UTC2023-01A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-073bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-073a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A070256-001NALOXONE HYDROCHLORIDE0.4MG/MLINJECTABLE / INJECTIONAPRS1987-01-07cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A070256-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A070256-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A070256-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A070256-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A070256-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A070256-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A070256-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A070256-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A070256-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A070256-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A070256-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A070256-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A070256-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A070256-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A070256-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A070256-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A070256-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A070256-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A070256-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A070256-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A070256-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A070256-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A070256-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A070256-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A070256-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A070256-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A070256-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A070256-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A070256-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A070256-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A070256-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A070256-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A070256-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A070256-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A070256-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A070256-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A070256-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A070256-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A070256-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A070256-001AP1cb3db0bc1861…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
50090-1836-0ML - Milliliter50090-1836ffc548ef-47ae-4976-b415-2de9b526647612018-10-11

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Naloxone HydrochlorideNALOXONE HYDROCHLORIDEHospira, Inc.8535cc84-ad4a-4d67-8480-fb5a2e3406f82026-05-27Warnings, Adverse reactionsExact identifier
application applno (ANDA): 070256
application number: ANDA070256
NALOXONE HCINALOXONE HCIHF Acquisition Co. LLC, DBA Health First73c1bad3-6ac3-8682-e053-2a91aa0a176a2024-01-27Warnings, Adverse reactionsExact identifier
application applno (ANDA): 070256
application number: ANDA070256

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
50090-1836-05009018360010 VIAL, SINGLE-DOSE in 1 CARTON (50090-1836-0) > 1 mL in 1 VIAL, SINGLE-DOSE2015-05-200000-00-00NoNoCurrent