TIMOLOL MALEATE

Product NDC
50090-1852
11-digit product format
500901852
Labeler code
50090
Product ID
50090-1852_7506af7c-3efd-4d0f-8a33-3dd8dc486935
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
timolol maleate
Dosage form
SOLUTION/ DROPS
Route
OPHTHALMIC
Labeler
A-S Medication Solutions
Application
ANDA077259
Marketing category
ANDA
Marketing start
2014-12-15
Marketing end
0000-00-00
Substance
TIMOLOL MALEATE
Active strength
5 mg/mL
Pharmacologic classes
Adrenergic beta-Antagonists [MoA],beta-Adrenergic Blocker [EPC]
NDC exclude flag
No
Listing certified through
2019-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct50090-1852DDiscontinued by firm2026-08-11
excluded packagepackage50090-185250090-1852-0DDiscontinued by firm2026-08-11

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 4 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded productproductd630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage50090-1852-0d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded productproductf5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage50090-1852-0f5e01cc5f278…a2eaf40c39c3…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A077259-001TIMOLOL MALEATETIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30
A077259-002TIMOLOL MALEATETIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A077259-001AT1
A077259-002AT1

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-3003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-302680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-305bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30d06236e962d9…
2024-10-29 15:01 UTC2024-10A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-3079d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-3079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-301e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-301e350fbaab3a…
2024-05-31 18:47 UTC2024-05A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-308072bd15b7f6…
2024-05-31 18:47 UTC2024-05A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-308072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-305c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-305c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-305d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-305d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-304b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-304b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT2008-04-3074a2ff9319b5…
2019-12-13 00:20 UTC2019-12A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-3074a2ff9319b5…
2022-03-09 01:35 UTC2022-03A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A077259-001TIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT2008-04-30782e0a99824c…
2021-12-28 21:50 UTC2021-12A077259-002TIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT12008-04-30782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A077259-001AT11011fe1cb6892…
2026-02-19 14:30 UTC2026-02A077259-002AT11011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A077259-001AT1131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A077259-002AT1131067a03dcf5…
2025-08-23 18:47 UTC2025-08A077259-001AT116a471c1ec25d…
2025-08-23 18:47 UTC2025-08A077259-002AT116a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A077259-001AT11fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A077259-002AT11fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A077259-001AT11b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A077259-002AT11b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A077259-001AT1103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A077259-002AT1103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A077259-001AT112680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A077259-002AT112680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A077259-001AT115bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A077259-002AT115bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A077259-001AT11d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A077259-002AT11d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A077259-001AT11d06236e962d9…
2024-10-29 15:01 UTC2024-10A077259-002AT11d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A077259-001AT1179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A077259-002AT1179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A077259-001AT11301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A077259-002AT11301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A077259-001AT111e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A077259-002AT111e350fbaab3a…
2024-05-31 18:47 UTC2024-05A077259-001AT118072bd15b7f6…
2024-05-31 18:47 UTC2024-05A077259-002AT118072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A077259-001AT115c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A077259-002AT115c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A077259-001AT115d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A077259-002AT115d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A077259-001AT114b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A077259-002AT114b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A077259-001AT174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A077259-002AT1174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A077259-001AT11bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A077259-002AT11bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A077259-001AT1782e0a99824c…
2021-12-28 21:50 UTC2021-12A077259-002AT11782e0a99824c…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
50090-1852-0ML - Milliliter50090-1852c60a779e-e01f-4c4a-b489-f3c811640ee812018-11-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
50090-1852TIMOLOL MALEATE SOLUTION/ DROPS [A-S MEDICATION SOLUTIONS]16Legacy NDC20230706_64561dfd-3704-4820-aef6-d0d26cef7255.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TIMOLOL MALEATETIMOLOL MALEATERising Pharma Holdings, Inc.2ed21930-1e05-46de-8acd-cb6f4798a7fa2025-05-09Warnings, Adverse reactionsExact identifier
application applno (ANDA): 077259
application number: ANDA077259