AMITRIPTYLINE HYDROCHLORIDE

Product NDC
50090-2840
11-digit product format
500902840
Labeler code
50090
Product ID
50090-2840_0e6d3575-3408-448c-a577-972d345c42df
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
AMITRIPTYLINE HYDROCHLORIDE
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
A-S Medication Solutions
Application
ANDA202446
Marketing category
ANDA
Marketing start
2014-12-05
Marketing end
0000-00-00
Substance
AMITRIPTYLINE HYDROCHLORIDE
Active strength
25 mg/1
Pharmacologic classes
Tricyclic Antidepressant [EPC]
NDC exclude flag
No
Listing certified through
2022-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 5 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct50090-2840DDiscontinued by firm2026-08-11
excluded packagepackage50090-284050090-2840-0DDiscontinued by firm2026-08-11
excluded packagepackage50090-284050090-2840-1DDiscontinued by firm2026-08-11
excluded packagepackage50090-284050090-2840-4DDiscontinued by firm2026-08-11
excluded packagepackage50090-284050090-2840-8DDiscontinued by firm2026-08-11

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 10 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded productproductd630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage50090-2840-1d630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage50090-2840-8d630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage50090-2840-4d630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage50090-2840-0d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded productproductf5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage50090-2840-1f5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage50090-2840-8f5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage50090-2840-4f5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage50090-2840-0f5e01cc5f278…a2eaf40c39c3…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 6 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A202446-001AMITRIPTYLINE HYDROCHLORIDEAMITRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2014-06-04
A202446-002AMITRIPTYLINE HYDROCHLORIDEAMITRIPTYLINE HYDROCHLORIDE25MGTABLET / ORALAB2014-06-04
A202446-003AMITRIPTYLINE HYDROCHLORIDEAMITRIPTYLINE HYDROCHLORIDE50MGTABLET / ORALAB2014-06-04
A202446-004AMITRIPTYLINE HYDROCHLORIDEAMITRIPTYLINE HYDROCHLORIDE75MGTABLET / ORALAB2014-06-04
A202446-005AMITRIPTYLINE HYDROCHLORIDEAMITRIPTYLINE HYDROCHLORIDE100MGTABLET / ORALAB2014-06-04
A202446-006AMITRIPTYLINE HYDROCHLORIDEAMITRIPTYLINE HYDROCHLORIDE150MGTABLET / ORALAB2014-06-04

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 6 matching rows.

Application-product, TE code table
Application-productTE code
A202446-001AB
A202446-002AB
A202446-003AB
A202446-004AB
A202446-005AB
A202446-006AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 7 · 246 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A202446-001AMITRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2014-06-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02A202446-002AMITRIPTYLINE HYDROCHLORIDE25MGTABLET / ORALAB2014-06-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02A202446-003AMITRIPTYLINE HYDROCHLORIDE50MGTABLET / ORALAB2014-06-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02A202446-004AMITRIPTYLINE HYDROCHLORIDE75MGTABLET / ORALAB2014-06-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02A202446-005AMITRIPTYLINE HYDROCHLORIDE100MGTABLET / ORALAB2014-06-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02A202446-006AMITRIPTYLINE HYDROCHLORIDE150MGTABLET / ORALAB2014-06-04011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202446-001AMITRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2014-06-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202446-002AMITRIPTYLINE HYDROCHLORIDE25MGTABLET / ORALAB2014-06-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202446-003AMITRIPTYLINE HYDROCHLORIDE50MGTABLET / ORALAB2014-06-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202446-004AMITRIPTYLINE HYDROCHLORIDE75MGTABLET / ORALAB2014-06-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202446-005AMITRIPTYLINE HYDROCHLORIDE100MGTABLET / ORALAB2014-06-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202446-006AMITRIPTYLINE HYDROCHLORIDE150MGTABLET / ORALAB2014-06-0431067a03dcf5…
2025-08-23 18:47 UTC2025-08A202446-001AMITRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2014-06-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08A202446-002AMITRIPTYLINE HYDROCHLORIDE25MGTABLET / ORALAB2014-06-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08A202446-003AMITRIPTYLINE HYDROCHLORIDE50MGTABLET / ORALAB2014-06-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08A202446-004AMITRIPTYLINE HYDROCHLORIDE75MGTABLET / ORALAB2014-06-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08A202446-005AMITRIPTYLINE HYDROCHLORIDE100MGTABLET / ORALAB2014-06-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08A202446-006AMITRIPTYLINE HYDROCHLORIDE150MGTABLET / ORALAB2014-06-046a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202446-001AMITRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2014-06-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202446-002AMITRIPTYLINE HYDROCHLORIDE25MGTABLET / ORALAB2014-06-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202446-003AMITRIPTYLINE HYDROCHLORIDE50MGTABLET / ORALAB2014-06-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202446-004AMITRIPTYLINE HYDROCHLORIDE75MGTABLET / ORALAB2014-06-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202446-005AMITRIPTYLINE HYDROCHLORIDE100MGTABLET / ORALAB2014-06-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202446-006AMITRIPTYLINE HYDROCHLORIDE150MGTABLET / ORALAB2014-06-04fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202446-001AMITRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2014-06-04b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202446-002AMITRIPTYLINE HYDROCHLORIDE25MGTABLET / ORALAB2014-06-04b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202446-003AMITRIPTYLINE HYDROCHLORIDE50MGTABLET / ORALAB2014-06-04b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202446-004AMITRIPTYLINE HYDROCHLORIDE75MGTABLET / ORALAB2014-06-04b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202446-005AMITRIPTYLINE HYDROCHLORIDE100MGTABLET / ORALAB2014-06-04b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202446-006AMITRIPTYLINE HYDROCHLORIDE150MGTABLET / ORALAB2014-06-04b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202446-001AMITRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2014-06-0403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202446-002AMITRIPTYLINE HYDROCHLORIDE25MGTABLET / ORALAB2014-06-0403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202446-003AMITRIPTYLINE HYDROCHLORIDE50MGTABLET / ORALAB2014-06-0403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202446-004AMITRIPTYLINE HYDROCHLORIDE75MGTABLET / ORALAB2014-06-0403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202446-005AMITRIPTYLINE HYDROCHLORIDE100MGTABLET / ORALAB2014-06-0403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202446-006AMITRIPTYLINE HYDROCHLORIDE150MGTABLET / ORALAB2014-06-0403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202446-001AMITRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2014-06-042680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202446-002AMITRIPTYLINE HYDROCHLORIDE25MGTABLET / ORALAB2014-06-042680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202446-003AMITRIPTYLINE HYDROCHLORIDE50MGTABLET / ORALAB2014-06-042680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202446-004AMITRIPTYLINE HYDROCHLORIDE75MGTABLET / ORALAB2014-06-042680178bc6a6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 7 · 246 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A202446-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A202446-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A202446-003AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A202446-004AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A202446-005AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A202446-006AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202446-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202446-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202446-003AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202446-004AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202446-005AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202446-006AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A202446-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A202446-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A202446-003AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A202446-004AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A202446-005AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A202446-006AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202446-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202446-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202446-003AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202446-004AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202446-005AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202446-006AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202446-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202446-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202446-003AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202446-004AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202446-005AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202446-006AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202446-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202446-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202446-003AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202446-004AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202446-005AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202446-006AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202446-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202446-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202446-003AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202446-004AB12680178bc6a6…

FDA-Initiated Inactive NDC Indexing#

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
50090-2840-0EA - Each50090-2840580b58c7-e54e-45a7-8d61-a1525946c74412020-03-10
50090-2840-1EA - Each50090-2840b7586ef2-b6da-4d4e-81f4-17e8b69dd93312019-04-11
50090-2840-4EA - Each50090-2840dca2eca0-c60d-4902-b686-14fa679316b212019-04-11
50090-2840-8EA - Each50090-2840fb7087a8-4a62-4c51-bea0-542ae637477c12020-03-10

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 7 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
AMITRIPTYLINE HYDROCHLORIDEAMITRIPTYLINE HYDROCHLORIDENorthwind Health Company, LLCe3afe026-7072-0a7d-e053-2995a90a52d42026-01-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202446
application number: ANDA202446
Amitriptyline HCLAMITRIPTYLINE HCLAdvanced Rx Pharmacy of Tennessee, LLCca66c2fc-6724-f4cd-e053-2995a90a42cf2024-12-31Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202446
application number: ANDA202446
AMITRIPTYLINE HYDROCHLORIDEAMITRIPTYLINE HYDROCHLORIDEBryant Ranch Prepack76d3f4fd-4603-4cfc-94ab-2e62c0bdae752024-08-19Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202446
application number: ANDA202446
AMITRIPTYLINE HYDROCHLORIDEAMITRIPTYLINE HYDROCHLORIDENuCare Pharmaceuticals,Inc.58ff9a82-5de6-a1b0-e053-2991aa0a84ba2024-07-18Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202446
application number: ANDA202446
AMITRIPTYLINE HYDROCHLORIDEAMITRIPTYLINE HYDROCHLORIDENuCare Pharmaceuticals,Inc.5a5a4040-5395-54ac-e053-2991aa0aa4ab2024-07-18Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202446
application number: ANDA202446
AMITRIPTYLINE HYDROCHLORIDEAMITRIPTYLINE HYDROCHLORIDEA-S Medication Solutions9440dd10-2f0d-42a7-a037-3ab8729708f62023-01-03Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202446
application number: ANDA202446
AMITRIPTYLINE HYDROCHLORIDEAMITRIPTYLINE HYDROCHLORIDEProficient Rx LPdf5aee40-ffa9-4cf3-ab5f-30253f43092b2022-05-02Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202446
application number: ANDA202446

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
50090-2840-05009028400030 TABLET, FILM COATED in 1 BOTTLE (50090-2840-0) 2018-08-100000-00-00NoNoCurrent
50090-2840-150090284001100 TABLET, FILM COATED in 1 BOTTLE (50090-2840-1) 2018-08-140000-00-00NoNoCurrent
50090-2840-45009028400460 TABLET, FILM COATED in 1 BOTTLE (50090-2840-4) 2017-02-030000-00-00NoNoCurrent
50090-2840-85009028400890 TABLET, FILM COATED in 1 BOTTLE (50090-2840-8) 2018-09-120000-00-00NoNoCurrent