Doxycycline Hyclate

Product NDC
50090-4592
Requested package NDC
50090-4592-8
11-digit product format
500904592
Labeler code
50090
Product ID
50090-4592_7f4b9f1b-fff7-4708-a503-3a427fc21f0c
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Doxycycline
Dosage form
CAPSULE
Route
ORAL
Labeler
A-S Medication Solutions
Application
ANDA207289
Marketing category
ANDA
Marketing start
2016-06-28
Marketing end
0000-00-00
Substance
DOXYCYCLINE HYCLATE
Active strength
100 mg/1
Pharmacologic classes
Tetracycline-class Drug [EPC],Tetracyclines [CS]
NDC exclude flag
No
Listing certified through
2022-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded packagepackage50090-459250090-4592-8IInactivated by FDA2026-08-03

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 15 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Snapshot, Source SHA-256 table
Captured / source dateSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-312ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-100efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09557ba5c1ecfa…9c80585c8c6e…
2024-05-28 21:12 UTC · source 2024-05-288af77b9d5b6f…d9bbb34c5368…
2024-05-15 03:39 UTC · source 2024-05-14834df4deac94…adcc014656a3…
2024-03-11 06:39 UTC · source 2024-03-081332a3947898…d4bfe170f9cd…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A207289-001DOXYCYCLINE HYCLATEDOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A207289-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-2731067a03dcf5…
2025-08-23 18:47 UTC2025-08A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-276a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-2703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-272680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-275bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-2779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-271e350fbaab3a…
2024-05-31 18:47 UTC2024-05A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-278072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-275c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-275d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-274b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-2774a2ff9319b5…
2022-03-09 01:35 UTC2022-03A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-2787673890dc5c…
2021-03-12 10:30 UTC2021-03A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-275aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-278869cabd3fbd…
2020-11-12 02:37 UTC2020-11A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27c0c555d07b60…
2019-12-14 00:12 UTC2019-12A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-273f01610625f2…
2019-09-15 20:21 UTC2019-09A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27b00525d2431f…
2019-07-19 19:46 UTC2019-07A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-276a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-271c564ffb4f44…
2023-12-20 04:57 UTC2023-12A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-279b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-273f0d92c62455…
2023-05-13 08:27 UTC2023-05A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27053a50430f4f…
2023-01-26 05:58 UTC2023-01A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-273bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-273a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A207289-001DOXYCYCLINE HYCLATEEQ 100MG BASECAPSULE / ORALAB2016-06-27cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A207289-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207289-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A207289-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207289-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207289-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207289-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207289-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207289-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207289-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A207289-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207289-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207289-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A207289-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A207289-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A207289-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A207289-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A207289-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A207289-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A207289-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A207289-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A207289-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A207289-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A207289-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A207289-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A207289-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A207289-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A207289-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A207289-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A207289-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A207289-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A207289-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A207289-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A207289-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A207289-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A207289-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A207289-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A207289-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A207289-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A207289-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A207289-001AB1cb3db0bc1861…

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
b4321c75-2e87-4d90-9726-9a28fb2293a3Product name320260112
5e99724e-0654-4aec-b7a2-0b9b10e312eeProduct name320250227
d2d36660-68ce-7e7d-0630-ec4b0d859fadProduct name620220921
a239f4dd-cf93-4660-b190-f97d000f249fProduct name720210607
a9d03566-caeb-4466-8021-74599b048880Product name320210604
12750814-20f7-4f35-b5fa-dbc8811ba858Product name920201007
00a5dbaa-1b7d-4e56-be0c-fedc7bbf5adeProduct name120200706
7b4b06ac-8c50-45f0-9556-293ea558a294Product name120180808
6a5b4392-5ab0-af0d-e0be-47b34e9dbb84Product name520171121
01a4aa74-7e05-63bd-bc10-1b5ceb111371Product name220171115
58b1278c-6dce-49b6-a05e-ea16f389acbaProduct name120160620

FDA-Initiated Inactive NDC Indexing#

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
50090-4592-0Doxycycline Hyclate40 in 1 BOTTLECAPSULE405
50090-4592-1Doxycycline Hyclate20 in 1 BOTTLECAPSULE205
50090-4592-2Doxycycline Hyclate10 in 1 BOTTLECAPSULE105
50090-4592-3Doxycycline Hyclate12 in 1 BOTTLECAPSULE125
50090-4592-4Doxycycline Hyclate4 in 1 BOTTLECAPSULE45
50090-4592-5Doxycycline Hyclate5 in 1 BOTTLECAPSULE55
50090-4592-6Doxycycline Hyclate14 in 1 BOTTLECAPSULE145
50090-4592-7Doxycycline Hyclate11 in 1 BOTTLECAPSULE115
50090-4592-8Doxycycline Hyclate500 in 1 BOTTLECAPSULE5005

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
50090-4592-1EA - Each50090-4592a976444b-787b-4d6b-8c61-b3dd109ee90712022-12-07

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
50090-4592DOXYCYCLINE HYCLATE (DOXYCYCLINE) CAPSULE [A-S MEDICATION SOLUTIONS]5Legacy NDC, 9 package rows20210417_34907713-088d-4434-b2cb-cb6c448092ef.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 5 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Doxycycline HyclateDOXYCYCLINEBryant Ranch Prepackf9a9a558-4063-4aa7-9191-3875c97cf49a2025-11-19Warnings, Adverse reactionsExact identifier
application applno (ANDA): 207289
application number: ANDA207289
Doxycycline HyclateDOXYCYCLINEAmneal Pharmaceuticals NY LLC49ecbf95-58e8-4f3c-b5d5-650a15d866cb2025-09-17Warnings, Adverse reactionsExact identifier
application applno (ANDA): 207289
application number: ANDA207289
Doxycycline HyclateDOXYCYCLINEAmneal Pharmaceuticals NY LLC79f3c026-7687-4a11-8d2e-03493531d3bf2025-09-10Warnings, Adverse reactionsExact identifier
application applno (ANDA): 207289
application number: ANDA207289
Doxycycline HyclateDOXYCYCLINE HYCLATEAdvanced Rx Pharmacy of Tennessee, LLCb4f2ab4f-c32b-6435-e053-2995a90a69b62024-12-31Warnings, Adverse reactionsExact identifier
application applno (ANDA): 207289
application number: ANDA207289
Doxycycline HyclateDOXYCYCLINEProficient Rx LPe2151005-fb4a-485d-88ad-b44c4594d5792022-06-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 207289
application number: ANDA207289

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1649988doxycycline hyclate 100 MG Oral CapsulePSN34907713-088d-4434-b2cb-cb6c448092ef5
1649988doxycycline hyclate 100 MG Oral CapsuleSCD34907713-088d-4434-b2cb-cb6c448092ef5
1649988doxycycline (as doxycycline hyclate) 100 MG Oral CapsuleSY34907713-088d-4434-b2cb-cb6c448092ef5

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
50090-4592-850090459208500 CAPSULE in 1 BOTTLE (50090-4592-8) 500 capsule2019-10-090000-00-00NoNoCurrent