Alprazolam

Product NDC
50090-5258
11-digit product format
500905258
Labeler code
50090
Product ID
50090-5258_c5e046d4-f03c-4a62-ab10-a07219433b33
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Alprazolam
Dosage form
TABLET
Route
ORAL
Labeler
A-S Medication Solutions
Application
ANDA207507
Marketing category
ANDA
Marketing start
2018-07-09
Marketing end
0000-00-00
Substance
ALPRAZOLAM
Active strength
1 mg/1
Pharmacologic classes
Benzodiazepine [EPC],Benzodiazepines [CS]
DEA schedule
CIV
NDC exclude flag
No
Listing certified through
2022-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 5 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct50090-5258DDiscontinued by firm2026-08-07
excluded packagepackage50090-525850090-5258-0DDiscontinued by firm2026-08-07
excluded packagepackage50090-525850090-5258-1DDiscontinued by firm2026-08-07
excluded packagepackage50090-525850090-5258-2DDiscontinued by firm2026-08-07
excluded packagepackage50090-525850090-5258-3DDiscontinued by firm2026-08-07

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 5 matching rows.

View current auxiliary records. · View the auxiliary file history.

Dataset, Scope, Package NDC table
DatasetScopePackage NDC
excluded productproduct
excluded packagepackage50090-5258-0
excluded packagepackage50090-5258-1
excluded packagepackage50090-5258-2
excluded packagepackage50090-5258-3

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 4 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A207507-001ALPRAZOLAMALPRAZOLAM0.25MGTABLET / ORAL2018-07-09
A207507-002ALPRAZOLAMALPRAZOLAM0.5MGTABLET / ORAL2018-07-09
A207507-003ALPRAZOLAMALPRAZOLAM1MGTABLET / ORAL2018-07-09
A207507-004ALPRAZOLAMALPRAZOLAM2MGTABLET / ORAL2018-07-09

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 5 · 164 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A207507-001ALPRAZOLAM0.25MGTABLET / ORAL2018-07-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02A207507-002ALPRAZOLAM0.5MGTABLET / ORAL2018-07-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02A207507-003ALPRAZOLAM1MGTABLET / ORAL2018-07-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02A207507-004ALPRAZOLAM2MGTABLET / ORAL2018-07-09011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207507-001ALPRAZOLAM0.25MGTABLET / ORAL2018-07-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207507-002ALPRAZOLAM0.5MGTABLET / ORAL2018-07-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207507-003ALPRAZOLAM1MGTABLET / ORAL2018-07-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207507-004ALPRAZOLAM2MGTABLET / ORAL2018-07-0931067a03dcf5…
2025-08-23 18:47 UTC2025-08A207507-001ALPRAZOLAM0.25MGTABLET / ORALAB2018-07-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08A207507-002ALPRAZOLAM0.5MGTABLET / ORALAB2018-07-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08A207507-003ALPRAZOLAM1MGTABLET / ORALAB2018-07-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08A207507-004ALPRAZOLAM2MGTABLET / ORALAB2018-07-096a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207507-001ALPRAZOLAM0.25MGTABLET / ORALAB2018-07-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207507-002ALPRAZOLAM0.5MGTABLET / ORALAB2018-07-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207507-003ALPRAZOLAM1MGTABLET / ORALAB2018-07-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207507-004ALPRAZOLAM2MGTABLET / ORALAB2018-07-09fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207507-001ALPRAZOLAM0.25MGTABLET / ORALAB2018-07-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207507-002ALPRAZOLAM0.5MGTABLET / ORALAB2018-07-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207507-003ALPRAZOLAM1MGTABLET / ORALAB2018-07-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207507-004ALPRAZOLAM2MGTABLET / ORALAB2018-07-09b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207507-001ALPRAZOLAM0.25MGTABLET / ORALAB2018-07-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207507-002ALPRAZOLAM0.5MGTABLET / ORALAB2018-07-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207507-003ALPRAZOLAM1MGTABLET / ORALAB2018-07-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207507-004ALPRAZOLAM2MGTABLET / ORALAB2018-07-0903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207507-001ALPRAZOLAM0.25MGTABLET / ORALAB2018-07-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207507-002ALPRAZOLAM0.5MGTABLET / ORALAB2018-07-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207507-003ALPRAZOLAM1MGTABLET / ORALAB2018-07-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207507-004ALPRAZOLAM2MGTABLET / ORALAB2018-07-092680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207507-001ALPRAZOLAM0.25MGTABLET / ORALAB2018-07-095bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207507-002ALPRAZOLAM0.5MGTABLET / ORALAB2018-07-095bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207507-003ALPRAZOLAM1MGTABLET / ORALAB2018-07-095bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207507-004ALPRAZOLAM2MGTABLET / ORALAB2018-07-095bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207507-001ALPRAZOLAM0.25MGTABLET / ORALAB2018-07-09d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207507-002ALPRAZOLAM0.5MGTABLET / ORALAB2018-07-09d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207507-003ALPRAZOLAM1MGTABLET / ORALAB2018-07-09d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207507-004ALPRAZOLAM2MGTABLET / ORALAB2018-07-09d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A207507-001ALPRAZOLAM0.25MGTABLET / ORALAB2018-07-09d06236e962d9…
2024-10-29 15:01 UTC2024-10A207507-002ALPRAZOLAM0.5MGTABLET / ORALAB2018-07-09d06236e962d9…
2024-10-29 15:01 UTC2024-10A207507-003ALPRAZOLAM1MGTABLET / ORALAB2018-07-09d06236e962d9…
2024-10-29 15:01 UTC2024-10A207507-004ALPRAZOLAM2MGTABLET / ORALAB2018-07-09d06236e962d9…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 152 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2025-08-23 18:47 UTC2025-08A207507-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A207507-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A207507-003AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A207507-004AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207507-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207507-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207507-003AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207507-004AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207507-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207507-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207507-003AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207507-004AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207507-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207507-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207507-003AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207507-004AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207507-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207507-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207507-003AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207507-004AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207507-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207507-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207507-003AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207507-004AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207507-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207507-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207507-003AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207507-004AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A207507-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A207507-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A207507-003AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A207507-004AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207507-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207507-002AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207507-003AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207507-004AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207507-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207507-002AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207507-003AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207507-004AB1301d65b070ca…

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
2ffbe5ef-58ff-88b9-e291-045e0f861f4fProduct name420180827
1f9e6d58-49d3-d9c1-e570-4bb0466a2c0bProduct name120140508
a1a11520-f3e2-68fa-8bd9-e80b271ef797Product name120140508
d153678e-a3c8-bad8-cfe0-385656dde0e7Product name120140508

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Related label table
NDCEffectiveRelated label
50090-5258-02023-02-07These highlights do not include all the information needed to use ALPRAZOLAM TABLETS safely and effectively. See full prescribing information for ALPRAZOLAM TABLETS. ALPRAZOLAM tablets, for oral use, CIV Initial U.S. Approval: 1981
50090-5258-12023-02-07These highlights do not include all the information needed to use ALPRAZOLAM TABLETS safely and effectively. See full prescribing information for ALPRAZOLAM TABLETS. ALPRAZOLAM tablets, for oral use, CIV Initial U.S. Approval: 1981
50090-5258-22023-02-07These highlights do not include all the information needed to use ALPRAZOLAM TABLETS safely and effectively. See full prescribing information for ALPRAZOLAM TABLETS. ALPRAZOLAM tablets, for oral use, CIV Initial U.S. Approval: 1981
50090-5258-32023-02-07These highlights do not include all the information needed to use ALPRAZOLAM TABLETS safely and effectively. See full prescribing information for ALPRAZOLAM TABLETS. ALPRAZOLAM tablets, for oral use, CIV Initial U.S. Approval: 1981
50090-5258-02023-01-30These highlights do not include all the information needed to use ALPRAZOLAM TABLETS safely and effectively. See full prescribing information for ALPRAZOLAM TABLETS. ALPRAZOLAM tablets, for oral use, CIV Initial U.S. Approval: 1981
50090-5258-12023-01-30These highlights do not include all the information needed to use ALPRAZOLAM TABLETS safely and effectively. See full prescribing information for ALPRAZOLAM TABLETS. ALPRAZOLAM tablets, for oral use, CIV Initial U.S. Approval: 1981
50090-5258-22023-01-30These highlights do not include all the information needed to use ALPRAZOLAM TABLETS safely and effectively. See full prescribing information for ALPRAZOLAM TABLETS. ALPRAZOLAM tablets, for oral use, CIV Initial U.S. Approval: 1981
50090-5258-32023-01-30These highlights do not include all the information needed to use ALPRAZOLAM TABLETS safely and effectively. See full prescribing information for ALPRAZOLAM TABLETS. ALPRAZOLAM tablets, for oral use, CIV Initial U.S. Approval: 1981

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
50090-5258-1EA - Each50090-5258b4e4596a-af94-4c16-9838-240a60e45fe812022-12-07
50090-5258-2EA - Each50090-5258f7fdb780-1b92-47b5-9b51-e9dced6c974e12022-12-07
50090-5258-3EA - Each50090-525827194a80-bd89-483d-9310-576166fd583e12022-12-07

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
50090-5258ALPRAZOLAM TABLET [A-S MEDICATION SOLUTIONS]14Legacy NDC20250406_e06b3bdd-ae21-4503-861e-11412bb7e7ea.zip

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
50090-5258-05009052580090 TABLET in 1 BOTTLE (50090-5258-0) 90 tablet2020-10-150000-00-00NoNoCurrent
50090-5258-15009052580130 TABLET in 1 BOTTLE (50090-5258-1) 30 tablet2020-10-150000-00-00NoNoCurrent
50090-5258-25009052580260 TABLET in 1 BOTTLE (50090-5258-2) 60 tablet2020-10-150000-00-00NoNoCurrent
50090-5258-350090525803100 TABLET in 1 BOTTLE (50090-5258-3) 100 tablet2020-10-150000-00-00NoNoCurrent