buprenorphine hydrochloride

Product NDC
50090-7559
11-digit product format
500907559
Labeler code
50090
Product ID
50090-7559_18fa8a54-6196-4635-a213-f78a9236f3d6
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
buprenorphine hydrochloride
Dosage form
TABLET
Route
SUBLINGUAL
Labeler
A-S Medication Solutions
Application
ANDA090622
Marketing category
ANDA
Marketing start
2023-10-12
Substance
BUPRENORPHINE HYDROCHLORIDE
Active strength
8 mg/1
Pharmacologic classes
Partial Opioid Agonist [EPC], Partial Opioid Agonists [MoA]
DEA schedule
CIII
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A090622-001BUPRENORPHINE HYDROCHLORIDEBUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-24
A090622-002BUPRENORPHINE HYDROCHLORIDEBUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-24

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A090622-001AB
A090622-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-24caaa826d4ba7…
2026-08-18 06:07:402026-07A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-24caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-24011fe1cb6892…
2026-02-19 14:30 UTC2026-02A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-24011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-2431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-246a471c1ec25d…
2025-08-23 18:47 UTC2025-08A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-246a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-24fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-24fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-24b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-24b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-2403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-2403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-242680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-242680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-245bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-245bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-24d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-24d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-24d06236e962d9…
2024-10-29 15:01 UTC2024-10A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-24d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-2479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-2479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-24301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-24301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-241e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-241e350fbaab3a…
2024-05-31 18:47 UTC2024-05A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-248072bd15b7f6…
2024-05-31 18:47 UTC2024-05A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-248072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-245c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-245c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-245d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-245d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-244b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-244b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-2474a2ff9319b5…
2019-12-13 00:20 UTC2019-12A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-2474a2ff9319b5…
2022-03-09 01:35 UTC2022-03A090622-001BUPRENORPHINE HYDROCHLORIDEEQ 2MG BASETABLET / SUBLINGUALAB2010-09-24bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A090622-002BUPRENORPHINE HYDROCHLORIDEEQ 8MG BASETABLET / SUBLINGUALAB2010-09-24bb7c543d1eb4…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A090622-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A090622-002AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A090622-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A090622-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090622-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090622-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A090622-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A090622-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090622-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090622-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090622-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090622-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090622-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090622-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090622-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090622-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090622-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090622-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090622-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090622-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A090622-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A090622-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090622-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090622-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090622-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090622-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090622-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090622-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A090622-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A090622-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090622-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090622-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A090622-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A090622-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A090622-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A090622-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A090622-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A090622-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A090622-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A090622-002AB1bb7c543d1eb4…

Additional Listing Data#

Finished product
Yes
Brand name base
buprenorphine hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BUPRENORPHINE HYDROCHLORIDE8 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
56W8MW3EN1Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
351265Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
c1398d85-d4bb-4426-8ecf-a50400910d81Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
68654759-f50b-79ef-24c5-544d94fe7d87Product name320251114
08a295bb-88df-4ab0-a120-a75a789a74f1Product name120231013
ab841ac7-728a-4fc9-be0a-35b96cecbf39Product name420230306
100316cc-94a9-474e-97ad-9b5c6ddec605Product name520230125
539bc5d3-546b-4af6-9c31-058ce6c459d3Product name220220210
b871fccd-1de6-4c7f-b9e5-045304641ee6Product name820220118
31e16ab2-c562-4617-a3e8-ed285320e16eProduct name120180201
4c23a34c-e8fc-424c-8fa0-ee064ba6eaefProduct name120170706
a5920611-4285-f024-69b9-39ff338b81eaProduct name520170609
3df867ed-9d48-45cf-bded-1394beaea0b1Product name320161206
973da5bf-b1f9-4de0-81ee-7ca066c98ca4Product name120160712

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
50090-7559-0buprenorphine hydrochloride30 in 1 BOTTLETABLET301

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
50090-7559-0EA - Each50090-7559911332fc-04b6-45a1-aab3-11dc3aabffa212025-06-13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
50090-7559BUPRENORPHINE HYDROCHLORIDE TABLET [A-S MEDICATION SOLUTIONS]1Current NDC, 1 package rows20250529_c1398d85-d4bb-4426-8ecf-a50400910d81.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
buprenorphine hydrochlorideBUPRENORPHINE HYDROCHLORIDEREMEDYREPACK INC.11686845-f5fd-4e96-8a4f-9b132bf488402026-07-07Warnings, Adverse reactionsExact identifier
application applno (ANDA): 090622
application number: ANDA090622
buprenorphine hydrochlorideBUPRENORPHINE HYDROCHLORIDEPAI Holdings, LLC dba PAI Pharma442831cf-9636-433a-9a12-e9a8cd31f72a2026-02-28Warnings, Adverse reactionsExact identifier
application applno (ANDA): 090622
application number: ANDA090622
buprenorphine hydrochlorideBUPRENORPHINE HYDROCHLORIDEA-S Medication Solutionsc1398d85-d4bb-4426-8ecf-a50400910d812025-05-28Warnings, Adverse reactionsExact identifier
application applno (ANDA): 090622
application number: ANDA090622
ndc (product): 50090-7559

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
351265buprenorphine HCl 8 MG Sublingual TabletPSNc1398d85-d4bb-4426-8ecf-a50400910d811
351265buprenorphine 8 MG Sublingual TabletSCDc1398d85-d4bb-4426-8ecf-a50400910d811
351265buprenorphine 8 MG (as buprenorphine HCl 8.64 MG) Sublingual TabletSYc1398d85-d4bb-4426-8ecf-a50400910d811

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
50090-7559-05009075590030 TABLET in 1 BOTTLE (50090-7559-0) 30 tablet2025-05-27NoNoCurrent