Itraconazole

Product NDC
50268-450
11-digit product format
502680450
Labeler code
50268
Product ID
50268-450_4823fc2f-1a82-9e54-e063-6294a90abb18
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Itraconazole
Dosage form
CAPSULE
Route
ORAL
Labeler
AvPAK
Application
ANDA205080
Marketing category
ANDA
Marketing start
2018-03-23
Substance
ITRACONAZOLE
Active strength
100 mg/1
Pharmacologic classes
Azole Antifungal [EPC], Azoles [CS], Breast Cancer Resistance Protein Inhibitors [MoA], Cytochrome P450 3A4 Inhibitors [MoA], P-Glycoprotein Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A205080-001ITRACONAZOLEITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A205080-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-2631067a03dcf5…
2025-08-23 18:47 UTC2025-08A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-266a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-2603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-262680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-265bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-2679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-261e350fbaab3a…
2024-05-31 18:47 UTC2024-05A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-268072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-265c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-265d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-264b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-2674a2ff9319b5…
2022-03-09 01:35 UTC2022-03A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-2687673890dc5c…
2021-03-12 10:30 UTC2021-03A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-265aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-268869cabd3fbd…
2020-11-12 02:37 UTC2020-11A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26c0c555d07b60…
2019-12-14 00:12 UTC2019-12A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-263f01610625f2…
2019-09-15 20:21 UTC2019-09A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26b00525d2431f…
2019-07-19 19:46 UTC2019-07A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-266a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-261c564ffb4f44…
2023-12-20 04:57 UTC2023-12A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-269b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-263f0d92c62455…
2023-05-13 08:27 UTC2023-05A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26053a50430f4f…
2023-01-26 05:58 UTC2023-01A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-263bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-263a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A205080-001ITRACONAZOLE100MGCAPSULE / ORALAB2016-09-26e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A205080-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A205080-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A205080-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A205080-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A205080-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A205080-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A205080-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A205080-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A205080-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A205080-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A205080-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A205080-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A205080-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A205080-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A205080-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A205080-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A205080-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A205080-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A205080-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A205080-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A205080-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A205080-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A205080-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A205080-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A205080-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A205080-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A205080-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A205080-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A205080-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A205080-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A205080-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A205080-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A205080-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A205080-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A205080-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A205080-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A205080-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A205080-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A205080-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A205080-001AB1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
Itraconazole
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ITRACONAZOLE100 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
304NUG5GF4Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
311204Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
68165d90-953c-e2f5-e053-2a91aa0ada25Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
9d9fdd44-2f2e-2968-36a7-2e5aa5ad971eProduct name420210511
177ecfe5-1d67-dab4-615e-cac2b457a3c1Product name820191002
9d180e3e-4d31-448b-8857-92c67ed2461aProduct name120190410
7ac2304e-2df8-d230-3b61-1cd07aab1554Product name120140508
ed912195-5da0-0f2f-6f4b-3ef17710cbe3Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
50268-450-11Itraconazole1 in 1 BLISTER PACKCAPSULE117
50268-450-12Itraconazole20 in 1 BOX, UNIT-DOSECAPSULE2017

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
50268-450-11EA - Each50268-4502ef1f8e5-c1bb-4a41-8cab-4748c886d0b612018-05-09
50268-450-12EA - Each50268-4508c62df80-4850-4659-9e54-06ea7343e3b712018-05-09

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
50268-450ITRACONAZOLE CAPSULE [AVPAK]15Current NDC, Legacy NDC, 2 package rows20240110_68165d90-953c-e2f5-e053-2a91aa0ada25.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ItraconazoleITRACONAZOLEAmneal Pharmaceuticals LLC2ab38a8a-3708-4b97-9f7f-8e554a15348d2026-07-22Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 205080
application number: ANDA205080
ItraconazoleITRACONAZOLEAvPAK68165d90-953c-e2f5-e053-2a91aa0ada252026-01-11Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 205080
application number: ANDA205080
ndc (product): 50268-450
ItraconazoleITRACONAZOLEAmerican Health Packaginge564067e-e469-4c51-9076-75f89f5c5cdf2025-03-27Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 205080
application number: ANDA205080

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
311204itraconazole 100 MG Oral CapsulePSN68165d90-953c-e2f5-e053-2a91aa0ada2517
311204itraconazole 100 MG Oral CapsuleSCD68165d90-953c-e2f5-e053-2a91aa0ada2517
311204ICNZ 100 MG Oral CapsuleSY68165d90-953c-e2f5-e053-2a91aa0ada2517

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
50268-450-11502680450111 in 1 BLISTER PACKHistorical
50268-450-125026804501220 BLISTER PACK in 1 BOX, UNIT-DOSE (50268-450-12) / 1 CAPSULE in 1 BLISTER PACK (50268-450-11) 20 blister pack2018-03-230000-00-00NoNoCurrent