SPORANOX

Product NDC
50458-290
11-digit product format
504580290
Labeler code
50458
Product ID
50458-290_b5d1c275-8665-4f63-8232-e34a02c998c7
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
ITRACONAZOLE
Dosage form
CAPSULE
Route
ORAL
Labeler
Janssen Pharmaceuticals, Inc.
Application
NDA020083
Marketing category
NDA
Marketing start
1992-09-11
Marketing end
2026-11-30
Substance
ITRACONAZOLE
Active strength
100 mg/1
Pharmacologic classes
Azole Antifungal [EPC], Azoles [CS], Breast Cancer Resistance Protein Inhibitors [MoA], Cytochrome P450 3A4 Inhibitors [MoA], P-Glycoprotein Inhibitors [MoA]
NDC exclude flag
No
Current FDA listing
Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded packagepackage50458-29050458-290-28DDiscontinued by firm2026-08-17

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 12 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Snapshot, Source SHA-256 table
Captured / source dateSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-312ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-100efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N020083-001SPORANOXITRACONAZOLE100MGCAPSULE / ORALABRLD, RS1992-09-11

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N020083-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-1131067a03dcf5…
2025-08-23 18:47 UTC2025-08N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-116a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-1103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-112680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-115bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-1179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-111e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-118072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-115c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-115d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-114b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-1174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-1187673890dc5c…
2021-03-12 10:30 UTC2021-03N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-115aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-118869cabd3fbd…
2020-11-12 02:37 UTC2020-11N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11c0c555d07b60…
2019-12-14 00:12 UTC2019-12N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-113f01610625f2…
2019-09-15 20:21 UTC2019-09N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11b00525d2431f…
2019-07-19 19:46 UTC2019-07N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-116a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-111c564ffb4f44…
2023-12-20 04:57 UTC2023-12N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-119b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-113f0d92c62455…
2023-05-13 08:27 UTC2023-05N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11053a50430f4f…
2023-01-26 05:58 UTC2023-01N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-113bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-113a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N020083-001SPORANOX100MGCAPSULE / ORALABRLD, RS1992-09-11e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N020083-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N020083-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020083-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N020083-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020083-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020083-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020083-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020083-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020083-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020083-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020083-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020083-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020083-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020083-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020083-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020083-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020083-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020083-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N020083-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N020083-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N020083-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N020083-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03N020083-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N020083-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11N020083-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12N020083-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09N020083-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07N020083-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N020083-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N020083-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N020083-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N020083-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N020083-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N020083-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N020083-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05N020083-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01N020083-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N020083-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N020083-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N020083-001AB1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
SPORANOX

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ITRACONAZOLE100 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
304NUG5GF4Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
311204Internal RxNorm lookup
833164Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
a4d555fa-787c-40fb-bb7d-b0d4f7318fd0Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
9d9fdd44-2f2e-2968-36a7-2e5aa5ad971eProduct name420210511
177ecfe5-1d67-dab4-615e-cac2b457a3c1Product name820191002
9d180e3e-4d31-448b-8857-92c67ed2461aProduct name120190410
7ac2304e-2df8-d230-3b61-1cd07aab1554Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
50458-290-01SPORANOX10 in 1 BLISTER PACKCAPSULE1030
50458-290-01SPORANOX3 in 1 CARTONCAPSULE330
50458-290-04SPORANOX30 in 1 BOTTLECAPSULE3030
50458-290-28SPORANOX7 in 1 DOSE PACKCAPSULE730
50458-290-28SPORANOX1 in 1 POUCHCAPSULE130

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
50458-290-01EA - Each50458-29092a6556f-56e2-4290-9bee-d5345a66aaee12012-07-24
50458-290-04EA - Each50458-290be6ec4d3-3eda-4a4e-90e2-eeea29eb777e12012-07-24
50458-290-28EA - Each50458-2901184dde1-36b4-450e-9694-f347edc17d1412012-07-24

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
50458-290SPORANOX (ITRACONAZOLE) CAPSULE [JANSSEN PHARMACEUTICALS, INC.]27Current NDC, Legacy NDC, 5 package rows20250101_a4d555fa-787c-40fb-bb7d-b0d4f7318fd0.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
SPORANOXITRACONAZOLEJanssen Pharmaceuticals, Inc.a4d555fa-787c-40fb-bb7d-b0d4f7318fd02026-07-13Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 020083
application number: NDA020083
ndc (product): 50458-290
itraconazoleITRACONAZOLEPatriot Pharmaceuticals6242b7ad-eaa0-a524-b6e0-ec33e63407db2025-01-28Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 020083
application number: NDA020083

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
311204itraconazole 100 MG Oral CapsulePSNa4d555fa-787c-40fb-bb7d-b0d4f7318fd030
833164Sporanox 100 MG Oral CapsulePSNa4d555fa-787c-40fb-bb7d-b0d4f7318fd030
833164itraconazole 100 MG Oral Capsule [Sporanox]SBDa4d555fa-787c-40fb-bb7d-b0d4f7318fd030
311204itraconazole 100 MG Oral CapsuleSCDa4d555fa-787c-40fb-bb7d-b0d4f7318fd030
311204ICNZ 100 MG Oral CapsuleSYa4d555fa-787c-40fb-bb7d-b0d4f7318fd030
833164ICNZ 100 MG Oral Capsule [Sporanox]SYa4d555fa-787c-40fb-bb7d-b0d4f7318fd030
833164Sporanox 100 MG Oral CapsuleSYa4d555fa-787c-40fb-bb7d-b0d4f7318fd030

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
50458-290-01504580290013 BLISTER PACK in 1 CARTON (50458-290-01) / 10 CAPSULE in 1 BLISTER PACK3 blister pack1992-09-112026-11-30NoNoCurrent
50458-290-045045802900430 CAPSULE in 1 BOTTLE (50458-290-04) 30 capsule1992-09-112026-11-30NoNoCurrent
50458-290-28504580290287 POUCH in 1 DOSE PACK (50458-290-28) > 1 BLISTER PACK in 1 POUCH > 4 CAPSULE in 1 BLISTER PACK7 pouch1992-09-110000-00-00NoNoCurrent