Protriptyline hydrochloride

Product NDC
50383-960
11-digit product format
503830960
Labeler code
50383
Product ID
50383-960_df490f7b-6f10-48dc-9bd9-162746fd8f76
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Protriptyline hydrochloride
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Hi-Tech Pharmacal Co., Inc.
Application
ANDA202220
Marketing category
ANDA
Marketing start
2013-10-28
Marketing end
0000-00-00
Substance
PROTRIPTYLINE HYDROCHLORIDE
Active strength
10 mg/1
Pharmacologic classes
Tricyclic Antidepressant [EPC]
NDC exclude flag
No
Listing certified through
2021-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct50383-960DDiscontinued by firm2026-08-17
excluded packagepackage50383-96050383-960-10DDiscontinued by firm2026-08-17

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 24 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded productproductd630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage50383-960-10d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded productproductf5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage50383-960-10f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-31excluded productproduct2ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-31excluded packagepackage50383-960-102ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28excluded productproducta1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-28excluded packagepackage50383-960-10a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21excluded productproductcfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-21excluded packagepackage50383-960-10cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10excluded productproductcdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-10excluded packagepackage50383-960-10cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31excluded productproduct302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-31excluded packagepackage50383-960-10302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20excluded productproducted331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage50383-960-10ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-10excluded productproduct0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage50383-960-100efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08excluded productproductad56d346431e…cc804d4bbf1e…
2024-11-09 02:27 UTC · source 2024-11-08excluded packagepackage50383-960-10ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03excluded productproduct367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage50383-960-10367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09excluded productproduct557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage50383-960-10557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A202220-001PROTRIPTYLINE HYDROCHLORIDEPROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-19
A202220-002PROTRIPTYLINE HYDROCHLORIDEPROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALABRS2012-11-19

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A202220-001AB
A202220-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-19caaa826d4ba7…
2026-08-18 06:07:402026-07A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALABRS2012-11-19caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-19011fe1cb6892…
2026-02-19 14:30 UTC2026-02A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALABRS2012-11-19011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-1931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALABRS2012-11-1931067a03dcf5…
2025-08-23 18:47 UTC2025-08A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-196a471c1ec25d…
2025-08-23 18:47 UTC2025-08A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALABRS2012-11-196a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-19fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-19fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-19b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-19b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-1903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-1903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-192680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-192680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-195bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-195bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-19d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-19d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-19d06236e962d9…
2024-10-29 15:01 UTC2024-10A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-19d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-1979d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-1979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-19301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-19301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-191e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-191e350fbaab3a…
2024-05-31 18:47 UTC2024-05A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-198072bd15b7f6…
2024-05-31 18:47 UTC2024-05A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-198072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-195c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-195c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-195d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-195d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-194b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-194b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-1974a2ff9319b5…
2019-12-13 00:20 UTC2019-12A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-1974a2ff9319b5…
2022-03-09 01:35 UTC2022-03A202220-001PROTRIPTYLINE HYDROCHLORIDE5MGTABLET / ORALAB2012-11-19bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A202220-002PROTRIPTYLINE HYDROCHLORIDE10MGTABLET / ORALAB2012-11-19bb7c543d1eb4…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A202220-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A202220-002AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A202220-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A202220-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202220-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202220-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A202220-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A202220-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202220-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202220-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202220-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202220-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202220-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202220-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202220-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202220-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202220-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202220-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202220-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202220-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A202220-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A202220-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202220-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202220-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202220-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202220-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202220-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202220-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A202220-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A202220-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202220-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202220-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A202220-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A202220-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A202220-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A202220-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A202220-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A202220-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A202220-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A202220-002AB1bb7c543d1eb4…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
50383-960-10EA - Each50383-96024e10bbf-8351-4b57-9851-97281acee6ca12013-12-02

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
PROTRIPTYLINE HYDROCHLORIDEACTIVE INGREDIENT44665V00O8PROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
PROTRIPTYLINEACTIVE MOIETY4NDU154T12PROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
CALCIUM PHOSPHATE, DIBASIC, ANHYDROUSINACTIVE INGREDIENTL11K75P92JPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61UPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
FD&C YELLOW NO. 6INACTIVE INGREDIENTH77VEI93A8PROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
HYPROMELLOSESINACTIVE INGREDIENT3NXW29V3WOPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
LACTOSE MONOHYDRATEINACTIVE INGREDIENTEWQ57Q8I5XPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30PROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
POLYETHYLENE GLYCOLSINACTIVE INGREDIENT3WJQ0SDW1APROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
POLYSORBATE 20INACTIVE INGREDIENT7T1F30V5YHPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
POLYSORBATE 80INACTIVE INGREDIENT6OZP39ZG8HPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
SODIUM STARCH GLYCOLATE TYPE A POTATOINACTIVE INGREDIENT5856J3G2A2PROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
STARCH, POTATOINACTIVE INGREDIENT8I089SAH3TPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
STARCH, TAPIOCAINACTIVE INGREDIENT24SC3U704IPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
TITANIUM DIOXIDEINACTIVE INGREDIENT15FIX9V2JPPROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1
TRIACETININACTIVE INGREDIENTXHX3C3X673PROTRIPTYLINE HYDROCHLORIDE TABLET, FILM COATED [HI-TECH PHARMACAL CO., INC.]1

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Protriptyline HydrochloridePROTRIPTYLINE HYDROCHLORIDEEpic Pharma, LLCc6c7c39e-e510-4f4a-bf7a-926f0e075d3a2023-07-25Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202220
application number: ANDA202220

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
50383-960-1050383096010100 TABLET, FILM COATED in 1 BOTTLE (50383-960-10) 2013-10-280000-00-00NoNoCurrent