ENTECAVIR

Product NDC
50771-013
11-digit product format
507710013
Labeler code
50771
Product ID
50771-013_4502e388-5064-bd87-e063-6294a90a4b1c
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
entecavir
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Yaopharma Co., Ltd.
Application
ANDA212201
Marketing category
ANDA
Marketing start
2023-07-01
Substance
ENTECAVIR
Active strength
.5 mg/1
Pharmacologic classes
Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC], Nucleoside Analog [EXT], Nucleoside Reverse Transcriptase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 9 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2024-05-28 21:12 UTC · source 2024-05-28excluded productproduct8af77b9d5b6f…d9bbb34c5368…
2024-05-28 21:12 UTC · source 2024-05-28excluded packagepackage50771-013-018af77b9d5b6f…d9bbb34c5368…
2024-05-28 21:12 UTC · source 2024-05-28excluded packagepackage50771-013-028af77b9d5b6f…d9bbb34c5368…
2024-05-15 03:39 UTC · source 2024-05-14excluded productproduct834df4deac94…adcc014656a3…
2024-05-15 03:39 UTC · source 2024-05-14excluded packagepackage50771-013-01834df4deac94…adcc014656a3…
2024-05-15 03:39 UTC · source 2024-05-14excluded packagepackage50771-013-02834df4deac94…adcc014656a3…
2024-03-11 06:39 UTC · source 2024-03-08excluded productproduct1332a3947898…d4bfe170f9cd…
2024-03-11 06:39 UTC · source 2024-03-08excluded packagepackage50771-013-011332a3947898…d4bfe170f9cd…
2024-03-11 06:39 UTC · source 2024-03-08excluded packagepackage50771-013-021332a3947898…d4bfe170f9cd…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A212201-001ENTECAVIRENTECAVIR0.5MGTABLET / ORAL2019-11-04
A212201-002ENTECAVIRENTECAVIR1MGTABLET / ORAL2019-11-04

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 78 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-04011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-0431067a03dcf5…
2025-08-23 18:47 UTC2025-08A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-046a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-04fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-04b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-04b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-0403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-0403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-042680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-042680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-045bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-045bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-04d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-04d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-04d06236e962d9…
2024-10-29 15:01 UTC2024-10A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-04d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-0479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-0479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-04301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-04301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-041e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-041e350fbaab3a…
2024-05-31 18:47 UTC2024-05A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-048072bd15b7f6…
2024-05-31 18:47 UTC2024-05A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-048072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-045c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-045c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-045d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-045d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-044b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-044b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A212201-001ENTECAVIR0.5MGTABLET / ORALAB2019-11-0474a2ff9319b5…
2019-12-13 00:20 UTC2019-12A212201-002ENTECAVIR1MGTABLET / ORALAB2019-11-0474a2ff9319b5…
2022-03-09 01:35 UTC2022-03A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-04bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-04bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A212201-001ENTECAVIR0.5MGTABLET / ORAL2019-11-04782e0a99824c…
2021-12-28 21:50 UTC2021-12A212201-002ENTECAVIR1MGTABLET / ORAL2019-11-04782e0a99824c…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2019-12-13 00:20 UTC2019-12A212201-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A212201-002AB174a2ff9319b5…
2019-12-14 00:12 UTC2019-12A212201-001AB13f01610625f2…
2019-12-14 00:12 UTC2019-12A212201-002AB13f01610625f2…

Additional Listing Data#

Finished product
Yes
Brand name base
ENTECAVIR
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ENTECAVIR.5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
5968Y6H45MInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
485434Internal RxNorm lookup
485436Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
73dea2a4-a596-477f-b66d-5a80dd019837Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
362d7abb-94e6-4c60-9a58-266894157713Product name120231023
bf657fd6-5fee-0845-3354-1dada0e72202Product name920190701
816b97af-edc5-4060-aff1-b814bdbcad50Product name120190415
419aab54-5d5a-4146-9453-026d4a9991beProduct name220170525
89dac932-b90a-4410-9ab1-84c53e57de25Product name120150316
d723478e-ad4a-ec23-6bd7-cfe33e1e3840Product name120140508

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Related label table
NDCEffectiveRelated label
50771-013-012024-06-24HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use ENTECAVIR TABLETS safely and effectively. See full prescribing information for ENTECAVIR TABLETS. ENTECAVIR TABLETS, for oral use Initial U.S. Approval: 2005
50771-013-012024-06-24HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use ENTECAVIR TABLETS safely and effectively. See full prescribing information for ENTECAVIR TABLETS. ENTECAVIR TABLETS, for oral use Initial U.S. Approval: 2005
50771-013-022024-06-24HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use ENTECAVIR TABLETS safely and effectively. See full prescribing information for ENTECAVIR TABLETS. ENTECAVIR TABLETS, for oral use Initial U.S. Approval: 2005
50771-013-022024-06-24HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use ENTECAVIR TABLETS safely and effectively. See full prescribing information for ENTECAVIR TABLETS. ENTECAVIR TABLETS, for oral use Initial U.S. Approval: 2005
50771-013-012024-01-30HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use ENTECAVIR TABLETS safely and effectively. See full prescribing information for ENTECAVIR TABLETS. ENTECAVIR TABLETS, for oral use Initial U.S. Approval: 2005
50771-013-012024-01-30HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use ENTECAVIR TABLETS safely and effectively. See full prescribing information for ENTECAVIR TABLETS. ENTECAVIR TABLETS, for oral use Initial U.S. Approval: 2005
50771-013-022024-01-30HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use ENTECAVIR TABLETS safely and effectively. See full prescribing information for ENTECAVIR TABLETS. ENTECAVIR TABLETS, for oral use Initial U.S. Approval: 2005
50771-013-022024-01-30HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use ENTECAVIR TABLETS safely and effectively. See full prescribing information for ENTECAVIR TABLETS. ENTECAVIR TABLETS, for oral use Initial U.S. Approval: 2005

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
50771-013-01ENTECAVIR30 in 1 BOTTLETABLET, FILM COATED3012
50771-013-02ENTECAVIR90 in 1 BOTTLETABLET, FILM COATED9012

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
50771-013ENTECAVIR TABLET, FILM COATED [YAOPHARMA CO., LTD.]10Current NDC, Legacy NDC, 2 package rows20241220_73dea2a4-a596-477f-b66d-5a80dd019837.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ENTECAVIRENTECAVIRYaopharma Co., Ltd.73dea2a4-a596-477f-b66d-5a80dd0198372026-07-07Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 212201
application number: ANDA212201
ndc (product): 50771-013

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
485434entecavir 0.5 MG Oral TabletPSN73dea2a4-a596-477f-b66d-5a80dd01983712
485436entecavir 1 MG Oral TabletPSN73dea2a4-a596-477f-b66d-5a80dd01983712
485434entecavir 0.5 MG Oral TabletSCD73dea2a4-a596-477f-b66d-5a80dd01983712
485436entecavir 1 MG Oral TabletSCD73dea2a4-a596-477f-b66d-5a80dd01983712

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
50771-013-015077100130130 TABLET, FILM COATED in 1 BOTTLE (50771-013-01) 2023-07-010000-00-00NoNoCurrent
50771-013-025077100130290 TABLET, FILM COATED in 1 BOTTLE (50771-013-02) 2023-07-010000-00-00NoNoCurrent