Metolazone

Product NDC
51079-024
11-digit product format
510790024
Labeler code
51079
Product ID
51079-024_3a866716-12c7-4380-e063-6394a90ae975
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
metolazone
Dosage form
TABLET
Route
ORAL
Labeler
Mylan Institutional Inc.
Application
ANDA076698
Marketing category
ANDA
Marketing start
2005-02-01
Substance
METOLAZONE
Active strength
5 mg/1
Pharmacologic classes
Increased Diuresis [PE], Thiazide-like Diuretic [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A076698-001METOLAZONEMETOLAZONE2.5MGTABLET / ORALAB2003-12-23
A076698-002METOLAZONEMETOLAZONE5MGTABLET / ORALAB2004-10-19
A076698-003METOLAZONEMETOLAZONE10MGTABLET / ORALAB2004-10-19

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
A076698-001AB
A076698-002AB
A076698-003AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A076698-001METOLAZONE2.5MGTABLET / ORALAB2003-12-23011fe1cb6892…
2026-02-19 14:30 UTC2026-02A076698-002METOLAZONE5MGTABLET / ORALAB2004-10-19011fe1cb6892…
2026-02-19 14:30 UTC2026-02A076698-003METOLAZONE10MGTABLET / ORALAB2004-10-19011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076698-001METOLAZONE2.5MGTABLET / ORALAB2003-12-2331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076698-002METOLAZONE5MGTABLET / ORALAB2004-10-1931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076698-003METOLAZONE10MGTABLET / ORALAB2004-10-1931067a03dcf5…
2025-08-23 18:47 UTC2025-08A076698-001METOLAZONE2.5MGTABLET / ORALAB2003-12-236a471c1ec25d…
2025-08-23 18:47 UTC2025-08A076698-002METOLAZONE5MGTABLET / ORALAB2004-10-196a471c1ec25d…
2025-08-23 18:47 UTC2025-08A076698-003METOLAZONE10MGTABLET / ORALAB2004-10-196a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076698-001METOLAZONE2.5MGTABLET / ORALAB2003-12-23fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076698-002METOLAZONE5MGTABLET / ORALAB2004-10-19fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076698-003METOLAZONE10MGTABLET / ORALAB2004-10-19fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076698-001METOLAZONE2.5MGTABLET / ORALAB2003-12-23b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076698-002METOLAZONE5MGTABLET / ORALAB2004-10-19b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076698-003METOLAZONE10MGTABLET / ORALAB2004-10-19b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076698-001METOLAZONE2.5MGTABLET / ORALAB2003-12-2303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076698-002METOLAZONE5MGTABLET / ORALAB2004-10-1903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076698-003METOLAZONE10MGTABLET / ORALAB2004-10-1903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076698-001METOLAZONE2.5MGTABLET / ORALAB2003-12-232680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076698-002METOLAZONE5MGTABLET / ORALAB2004-10-192680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076698-003METOLAZONE10MGTABLET / ORALAB2004-10-192680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076698-001METOLAZONE2.5MGTABLET / ORALAB2003-12-235bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076698-002METOLAZONE5MGTABLET / ORALAB2004-10-195bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076698-003METOLAZONE10MGTABLET / ORALAB2004-10-195bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076698-001METOLAZONE2.5MGTABLET / ORALAB2003-12-23d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076698-002METOLAZONE5MGTABLET / ORALAB2004-10-19d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076698-003METOLAZONE10MGTABLET / ORALAB2004-10-19d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076698-001METOLAZONE2.5MGTABLET / ORALAB2003-12-23d06236e962d9…
2024-10-29 15:01 UTC2024-10A076698-002METOLAZONE5MGTABLET / ORALAB2004-10-19d06236e962d9…
2024-10-29 15:01 UTC2024-10A076698-003METOLAZONE10MGTABLET / ORALAB2004-10-19d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076698-001METOLAZONE2.5MGTABLET / ORALAB2003-12-2379d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076698-002METOLAZONE5MGTABLET / ORALAB2004-10-1979d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076698-003METOLAZONE10MGTABLET / ORALAB2004-10-1979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076698-001METOLAZONE2.5MGTABLET / ORALAB2003-12-23301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076698-002METOLAZONE5MGTABLET / ORALAB2004-10-19301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076698-003METOLAZONE10MGTABLET / ORALAB2004-10-19301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076698-001METOLAZONE2.5MGTABLET / ORALAB2003-12-231e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076698-002METOLAZONE5MGTABLET / ORALAB2004-10-191e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076698-003METOLAZONE10MGTABLET / ORALAB2004-10-191e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076698-001METOLAZONE2.5MGTABLET / ORALAB2003-12-238072bd15b7f6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A076698-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A076698-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A076698-003AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076698-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076698-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076698-003AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A076698-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A076698-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A076698-003AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076698-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076698-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076698-003AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076698-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076698-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076698-003AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076698-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076698-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076698-003AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076698-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076698-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076698-003AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076698-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076698-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076698-003AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076698-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076698-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076698-003AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076698-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A076698-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A076698-003AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076698-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076698-002AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076698-003AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076698-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076698-002AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076698-003AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076698-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076698-002AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076698-003AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076698-001AB18072bd15b7f6…

Additional Listing Data#

Finished product
Yes
Brand name base
Metolazone
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
METOLAZONE5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
TZ7V40X7VXInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
197979Internal RxNorm lookup
311671Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
e5fe856e-7fd6-47fb-87f7-7c1c621f50a0Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
4e48c581-6027-290d-65f0-1b09c39dc1e8Product name620250625

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
51079-024-01Metolazone1 in 1 BLISTER PACKTABLET17
51079-024-20Metolazone100 in 1 CARTONTABLET1007

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
51079-024-01EA - Each51079-0245862600d-0954-44bc-a97a-015ef7adce9212012-07-24
51079-024-20EA - Each51079-024bb1845ec-db1b-4851-aa4f-27c28410443812012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
METOLAZONEACTIVE INGREDIENTTZ7V40X7VXMETOLAZONE TABLET [MYLAN INSTITUTIONAL INC.]2
METOLAZONEACTIVE MOIETYTZ7V40X7VXMETOLAZONE TABLET [MYLAN INSTITUTIONAL INC.]2
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61UMETOLAZONE TABLET [MYLAN INSTITUTIONAL INC.]2
FD&C YELLOW NO. 6INACTIVE INGREDIENTH77VEI93A8METOLAZONE TABLET [MYLAN INSTITUTIONAL INC.]2
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30METOLAZONE TABLET [MYLAN INSTITUTIONAL INC.]2
SILICON DIOXIDEINACTIVE INGREDIENTETJ7Z6XBU4METOLAZONE TABLET [MYLAN INSTITUTIONAL INC.]2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
51079-024METOLAZONE TABLET [MYLAN INSTITUTIONAL INC.]6Current NDC, Legacy NDC, 2 package rows20211217_e5fe856e-7fd6-47fb-87f7-7c1c621f50a0.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
MetolazoneMETOLAZONESafecor Health LLCefa8795e-2c89-4519-b49f-13146fb9ded12026-03-02Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076698
application number: ANDA076698
MetolazoneMETOLAZONEMylan Institutional Inc.e5fe856e-7fd6-47fb-87f7-7c1c621f50a02025-07-22Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076698
application number: ANDA076698
ndc (product): 51079-024
MetolazoneMETOLAZONEMylan Pharmaceuticals Inc.6639d111-eb21-4997-b964-f5c61bc088f22019-10-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076698
application number: ANDA076698
MetolazoneMETOLAZONEAphena Pharma Solutions - Tennessee, LLC80500d09-e1c5-450a-9806-f4f13843229d2017-12-14Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076698
application number: ANDA076698

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
197979metOLazone 2.5 MG Oral TabletPSNe5fe856e-7fd6-47fb-87f7-7c1c621f50a07
311671metOLazone 5 MG Oral TabletPSNe5fe856e-7fd6-47fb-87f7-7c1c621f50a07
197979metolazone 2.5 MG Oral TabletSCDe5fe856e-7fd6-47fb-87f7-7c1c621f50a07
311671metolazone 5 MG Oral TabletSCDe5fe856e-7fd6-47fb-87f7-7c1c621f50a07

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
51079-024-01510790024011 in 1 BLISTER PACKHistorical
51079-024-2051079002420100 BLISTER PACK in 1 CARTON (51079-024-20) / 1 TABLET in 1 BLISTER PACK (51079-024-01) 100 blister pack2005-02-010000-00-00NoNoCurrent