Chlorthalidone

Product NDC
51224-018
11-digit product format
512240018
Labeler code
51224
Product ID
51224-018_98c8ff40-9e00-4793-ba69-5e36ced32984
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Chlorthalidone
Dosage form
TABLET
Route
ORAL
Labeler
TAGI Pharma, Inc.
Application
ANDA212878
Marketing category
ANDA
Marketing start
2022-08-05
Substance
CHLORTHALIDONE
Active strength
25 mg/1
Pharmacologic classes
Increased Diuresis [PE], Thiazide-like Diuretic [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A212878-001CHLORTHALIDONECHLORTHALIDONE25MGTABLET / ORALAB2022-02-24

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A212878-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-24011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-246a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-24fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-24b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-2403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-242680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-245bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-24d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-24d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-2479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-24301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-241e350fbaab3a…
2024-05-31 18:47 UTC2024-05A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-248072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-245c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-245d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-244b0b4de00fa7…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-246a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-241c564ffb4f44…
2023-12-20 04:57 UTC2023-12A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-24ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-24a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-249b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-24a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-243f0d92c62455…
2023-05-13 08:27 UTC2023-05A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-24053a50430f4f…
2023-01-26 05:58 UTC2023-01A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-243bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-243a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-24f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-24e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-24cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A212878-001CHLORTHALIDONE25MGTABLET / ORALAB2022-02-24a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A212878-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A212878-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A212878-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A212878-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A212878-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A212878-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A212878-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A212878-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A212878-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A212878-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A212878-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A212878-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A212878-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A212878-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A212878-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A212878-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A212878-001AB14b0b4de00fa7…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A212878-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A212878-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A212878-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A212878-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A212878-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A212878-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A212878-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A212878-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A212878-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A212878-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A212878-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A212878-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A212878-001AB1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A212878-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Chlorthalidone
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CHLORTHALIDONE25 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
Q0MQD1073QInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
197499Internal RxNorm lookup
197500Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
bd92c59b-3a65-47c3-b3c8-37090b4ae464Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
83fe98fe-2a14-448c-9029-41f7600d1b0aProduct name120260105
0450926f-f624-49c2-83be-42807e8fbcd5Product name120251113
8525e779-537f-e5cc-2515-089ecce5f50fProduct name920221128
faf41ef3-b4b3-a29e-3b26-07c3009003bfProduct name520220517
3f5e2da3-8b99-f714-3261-2c998ee07b05Product name120140508
7667d8e2-e5be-36e1-4de7-231aa7fdaf5cProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
51224-018-50Chlorthalidone100 in 1 BOTTLETABLET1001
51224-018-70Chlorthalidone1000 in 1 BOTTLETABLET10001

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
51224-018-50EA - Each51224-018eab178f0-e82c-455b-b721-9408a215423f12022-10-06
51224-018-70EA - Each51224-0184674c132-d196-448c-a499-095fcf0233e712022-10-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
51224-018CHLORTHALIDONE TABLET [TAGI PHARMA, INC.]1Current NDC, Legacy NDC, 2 package rows20220805_bd92c59b-3a65-47c3-b3c8-37090b4ae464.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ChlorthalidoneCHLORTHALIDONEBryant Ranch Prepackd8373bde-c8c9-445a-8933-49394023414a2025-10-28Warnings, Adverse reactionsExact identifier
application applno (ANDA): 212878
application number: ANDA212878
ChlorthalidoneCHLORTHALIDONEBryant Ranch Prepackbcd2b6f8-533a-4f50-b3e6-80427e6c19ac2025-01-29Warnings, Adverse reactionsExact identifier
application applno (ANDA): 212878
application number: ANDA212878
ChlorthalidoneCHLORTHALIDONETAGI Pharma, Inc.bd92c59b-3a65-47c3-b3c8-37090b4ae4642022-06-22Warnings, Adverse reactionsExact identifier
application applno (ANDA): 212878
application number: ANDA212878
ndc (product): 51224-018

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
197499chlorthalidone 25 MG Oral TabletPSNbcd2b6f8-533a-4f50-b3e6-80427e6c19ac102
197499chlorthalidone 25 MG Oral TabletSCDbcd2b6f8-533a-4f50-b3e6-80427e6c19ac102
197499chlorthalidone 25 MG Oral TabletPSNd8373bde-c8c9-445a-8933-49394023414a100
197499chlorthalidone 25 MG Oral TabletSCDd8373bde-c8c9-445a-8933-49394023414a100
197499chlorthalidone 25 MG Oral TabletPSNbd92c59b-3a65-47c3-b3c8-37090b4ae4641
197500chlorthalidone 50 MG Oral TabletPSNbd92c59b-3a65-47c3-b3c8-37090b4ae4641
197499chlorthalidone 25 MG Oral TabletSCDbd92c59b-3a65-47c3-b3c8-37090b4ae4641
197500chlorthalidone 50 MG Oral TabletSCDbd92c59b-3a65-47c3-b3c8-37090b4ae4641

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
51224-018-5051224001850100 TABLET in 1 BOTTLE (51224-018-50) 100 tablet2022-08-050000-00-00NoNoCurrent
51224-018-70512240018701000 TABLET in 1 BOTTLE (51224-018-70) 1000 tablet2022-08-050000-00-00NoNoCurrent