EPLERENONE

Product NDC
51991-877
11-digit product format
519910877
Labeler code
51991
Product ID
51991-877_546c0ded-8c22-4840-b369-a3029dedc299
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
EPLERENONE
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Breckenridge Pharmaceutical, Inc.
Application
ANDA208283
Marketing category
ANDA
Marketing start
2018-09-18
Substance
EPLERENONE
Active strength
25 mg/1
Pharmacologic classes
Aldosterone Antagonist [EPC], Aldosterone Antagonists [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A208283-001EPLERENONEEPLERENONE25MGTABLET / ORALAB2018-09-14
A208283-002EPLERENONEEPLERENONE50MGTABLET / ORALAB2018-09-14

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A208283-001AB
A208283-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-14011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-1431067a03dcf5…
2025-08-23 18:47 UTC2025-08A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-146a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-14fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-14b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-14b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-1403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-1403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-142680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-142680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-145bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-145bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-14d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-14d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-14d06236e962d9…
2024-10-29 15:01 UTC2024-10A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-14d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-1479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-1479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-14301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-14301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-141e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-141e350fbaab3a…
2024-05-31 18:47 UTC2024-05A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-148072bd15b7f6…
2024-05-31 18:47 UTC2024-05A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-148072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-145c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-145c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-145d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-145d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-144b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-144b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-1474a2ff9319b5…
2019-12-13 00:20 UTC2019-12A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-1474a2ff9319b5…
2022-03-09 01:35 UTC2022-03A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-14bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-14bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A208283-001EPLERENONE25MGTABLET / ORALAB2018-09-14782e0a99824c…
2021-12-28 21:50 UTC2021-12A208283-002EPLERENONE50MGTABLET / ORALAB2018-09-14782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A208283-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A208283-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208283-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208283-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A208283-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A208283-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208283-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208283-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A208283-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A208283-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A208283-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A208283-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A208283-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A208283-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A208283-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A208283-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A208283-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A208283-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A208283-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A208283-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A208283-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A208283-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A208283-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A208283-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A208283-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A208283-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A208283-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A208283-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A208283-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A208283-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A208283-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A208283-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A208283-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A208283-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A208283-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A208283-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A208283-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A208283-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A208283-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12A208283-002AB1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
EPLERENONE
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
EPLERENONE25 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6995V82D0BInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
351256Internal RxNorm lookup
351257Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
e2a51c12-bdc2-4b3b-8e9e-bf363c2817edAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
6c046e2c-42d6-3179-f149-f207119f6ad5Product name620240530

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
51991-877-11EPLERENONE10 in 1 CARTONTABLET, FILM COATED108
51991-877-33EPLERENONE30 in 1 BOTTLETABLET, FILM COATED308
51991-877-90EPLERENONE90 in 1 BOTTLETABLET, FILM COATED908
51991-877-99EPLERENONE10 in 1 BLISTER PACKTABLET, FILM COATED108

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
51991-877-33EA - Each51991-8774252b7db-61e9-4a07-8b91-d7521978b4fc12018-10-11
51991-877-90EA - Each51991-877fe62da6b-cc94-40ef-842d-ea39ba67285812018-10-11

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
51991-877EPLERENONE TABLET, FILM COATED [BRECKENRIDGE PHARMACEUTICAL, INC.]6Current NDC, Legacy NDC, 4 package rows20240327_e2a51c12-bdc2-4b3b-8e9e-bf363c2817ed.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EPLERENONEEPLERENONEBreckenridge Pharmaceutical, Inc.e2a51c12-bdc2-4b3b-8e9e-bf363c2817ed2026-03-17Warnings, Adverse reactionsExact identifier
application applno (ANDA): 208283
application number: ANDA208283
ndc (product): 51991-877
EPLERENONEEPLERENONEAmerican Health Packaging3a3047f2-0155-4a07-955f-839a312cf8792025-05-19Warnings, Adverse reactionsExact identifier
application applno (ANDA): 208283
application number: ANDA208283

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
351256eplerenone 25 MG Oral TabletPSNe2a51c12-bdc2-4b3b-8e9e-bf363c2817ed8
351257eplerenone 50 MG Oral TabletPSNe2a51c12-bdc2-4b3b-8e9e-bf363c2817ed8
351256eplerenone 25 MG Oral TabletSCDe2a51c12-bdc2-4b3b-8e9e-bf363c2817ed8
351257eplerenone 50 MG Oral TabletSCDe2a51c12-bdc2-4b3b-8e9e-bf363c2817ed8
351256eplerenone 25 MG Oral TabletPSN3a3047f2-0155-4a07-955f-839a312cf8795
351256eplerenone 25 MG Oral TabletSCD3a3047f2-0155-4a07-955f-839a312cf8795

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
51991-877-115199108771110 BLISTER PACK in 1 CARTON (51991-877-11) / 10 TABLET, FILM COATED in 1 BLISTER PACK (51991-877-99) 10 blister pack2018-09-180000-00-00NoNoCurrent
51991-877-335199108773330 TABLET, FILM COATED in 1 BOTTLE (51991-877-33) 2018-09-180000-00-00NoNoCurrent
51991-877-905199108779090 TABLET, FILM COATED in 1 BOTTLE (51991-877-90) 2018-09-180000-00-00NoNoCurrent
51991-877-995199108779910 in 1 BLISTER PACKHistorical