Eplerenone

Product NDC
59762-1720
11-digit product format
597621720
Labeler code
59762
Product ID
59762-1720_f63a6d5f-f6ee-4cab-a796-d86aa1b6bf12
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
eplerenone
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Mylan Pharmaceuticals Inc.
Application
NDA021437
Marketing category
NDA AUTHORIZED GENERIC
Marketing start
2002-09-27
Marketing end
2026-08-31
Substance
EPLERENONE
Active strength
50 mg/1
Pharmacologic classes
Aldosterone Antagonist [EPC], Aldosterone Antagonists [MoA]
NDC exclude flag
No
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021437-001INSPRAEPLERENONE25MGTABLET / ORALABRLD2002-09-27
N021437-002INSPRAEPLERENONE50MGTABLET / ORALABRLD, RS2002-09-27
N021437-003INSPRAEPLERENONE100MGTABLET / ORAL2002-09-27

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
N021437-001AB
N021437-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N021437-001INSPRA25MGTABLET / ORALABRLD2002-09-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021437-002INSPRA50MGTABLET / ORALABRLD, RS2002-09-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021437-003INSPRA100MGTABLET / ORAL2002-09-27011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021437-001INSPRA25MGTABLET / ORALABRLD2002-09-2731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021437-002INSPRA50MGTABLET / ORALABRLD, RS2002-09-2731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021437-003INSPRA100MGTABLET / ORAL2002-09-2731067a03dcf5…
2025-08-23 18:47 UTC2025-08N021437-001INSPRA25MGTABLET / ORALABRLD2002-09-276a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021437-002INSPRA50MGTABLET / ORALABRLD, RS2002-09-276a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021437-003INSPRA100MGTABLET / ORAL2002-09-276a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021437-001INSPRA25MGTABLET / ORALABRLD2002-09-27fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021437-002INSPRA50MGTABLET / ORALABRLD, RS2002-09-27fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021437-003INSPRA100MGTABLET / ORAL2002-09-27fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021437-001INSPRA25MGTABLET / ORALABRLD2002-09-27b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021437-002INSPRA50MGTABLET / ORALABRLD, RS2002-09-27b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021437-003INSPRA100MGTABLET / ORAL2002-09-27b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021437-001INSPRA25MGTABLET / ORALABRLD2002-09-2703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021437-002INSPRA50MGTABLET / ORALABRLD, RS2002-09-2703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021437-003INSPRA100MGTABLET / ORAL2002-09-2703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021437-001INSPRA25MGTABLET / ORALABRLD2002-09-272680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021437-002INSPRA50MGTABLET / ORALABRLD, RS2002-09-272680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021437-003INSPRA100MGTABLET / ORAL2002-09-272680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021437-001INSPRA25MGTABLET / ORALABRLD2002-09-275bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021437-002INSPRA50MGTABLET / ORALABRLD, RS2002-09-275bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021437-003INSPRA100MGTABLET / ORAL2002-09-275bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021437-001INSPRA25MGTABLET / ORALABRLD2002-09-27d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021437-002INSPRA50MGTABLET / ORALABRLD, RS2002-09-27d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021437-003INSPRA100MGTABLET / ORAL2002-09-27d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021437-001INSPRA25MGTABLET / ORALABRLD2002-09-27d06236e962d9…
2024-10-29 15:01 UTC2024-10N021437-002INSPRA50MGTABLET / ORALABRLD, RS2002-09-27d06236e962d9…
2024-10-29 15:01 UTC2024-10N021437-003INSPRA100MGTABLET / ORAL2002-09-27d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021437-001INSPRA25MGTABLET / ORALABRLD2002-09-2779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021437-002INSPRA50MGTABLET / ORALABRLD, RS2002-09-2779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021437-003INSPRA100MGTABLET / ORAL2002-09-2779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021437-001INSPRA25MGTABLET / ORALABRLD2002-09-27301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021437-002INSPRA50MGTABLET / ORALABRLD, RS2002-09-27301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021437-003INSPRA100MGTABLET / ORAL2002-09-27301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021437-001INSPRA25MGTABLET / ORALABRLD2002-09-271e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021437-002INSPRA50MGTABLET / ORALABRLD, RS2002-09-271e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021437-003INSPRA100MGTABLET / ORAL2002-09-271e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021437-001INSPRA25MGTABLET / ORALABRLD2002-09-278072bd15b7f6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N021437-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021437-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021437-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021437-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N021437-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021437-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021437-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021437-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021437-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021437-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021437-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021437-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021437-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021437-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021437-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021437-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021437-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021437-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021437-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N021437-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021437-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021437-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021437-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021437-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021437-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021437-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021437-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021437-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021437-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021437-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021437-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021437-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021437-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021437-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021437-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021437-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021437-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021437-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12N021437-002AB1782e0a99824c…

Observed Orange Book patent history#

Patent history page 1 of 7 · 246 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2019-12-13 00:20 UTC2019-12N021437-00164105242019-11-05U-46774a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00167470202019-11-05U-58774a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00164100542019-12-08U-374a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00164100542019-12-08U-53774a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00164951652019-12-08U-374a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00164951652019-12-08U-53774a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00165340932019-12-08U-374a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00165340932019-12-08U-53774a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00165587072019-12-08U-537Drug product74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00171571012019-12-08U-664Drug product74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-0016410524*PED2020-05-05Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-0016747020*PED2020-05-05Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-0016410054*PED2020-06-08Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-0016495165*PED2020-06-08Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-0016534093*PED2020-06-08Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-0016558707*PED2020-06-08Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-0017157101*PED2020-06-08Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00264105242019-11-05U-46774a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00267470202019-11-05U-58774a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00264100542019-12-08U-374a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00264100542019-12-08U-53774a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00264951652019-12-08U-374a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00264951652019-12-08U-53774a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00265340932019-12-08U-374a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00265340932019-12-08U-53774a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00265587072019-12-08U-537Drug product74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00271571012019-12-08U-664Drug product74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-0026410524*PED2020-05-05Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-0026747020*PED2020-05-05Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-0026410054*PED2020-06-08Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-0026495165*PED2020-06-08Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-0026534093*PED2020-06-08Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-0026558707*PED2020-06-08Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-0027157101*PED2020-06-08Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00364105242019-11-05U-46774a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00367470202019-11-05U-58774a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00364100542019-12-08U-374a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00364100542019-12-08U-53774a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00364951652019-12-08U-374a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021437-00364951652019-12-08U-53774a2ff9319b5…

Additional Listing Data#

Finished product
Yes
Brand name base
Eplerenone

Active Ingredients#

Ingredient, Strength table
IngredientStrength
EPLERENONE50 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6995V82D0BInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
351256Internal RxNorm lookup
351257Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6d988699-95c2-46b9-8266-23fe7016f33bAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
6c046e2c-42d6-3179-f149-f207119f6ad5Product name620240530

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
59762-1720-1Eplerenone30 in 1 BOTTLETABLET, FILM COATED3025
59762-1720-2Eplerenone90 in 1 BOTTLETABLET, FILM COATED9025

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
59762-1720-1EA - Each59762-1720ecf0c846-d6d4-47f3-97fa-6640c075e49312012-07-24
59762-1720-2EA - Each59762-1720cbebc674-b7ff-4eb1-ad36-9d2830401a3812012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
EPLERENONEACTIVE INGREDIENT6995V82D0BEPLERENONE TABLET, FILM COATED [GREENSTONE LLC]10
EPLERENONEACTIVE MOIETY6995V82D0BEPLERENONE TABLET, FILM COATED [GREENSTONE LLC]10
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61UEPLERENONE TABLET, FILM COATED [GREENSTONE LLC]10
CROSCARMELLOSE SODIUMINACTIVE INGREDIENTM28OL1HH48EPLERENONE TABLET, FILM COATED [GREENSTONE LLC]10
FERRIC OXIDE REDINACTIVE INGREDIENT1K09F3G675EPLERENONE TABLET, FILM COATED [GREENSTONE LLC]10
FERRIC OXIDE YELLOWINACTIVE INGREDIENTEX438O2MRTEPLERENONE TABLET, FILM COATED [GREENSTONE LLC]10
HYPROMELLOSESINACTIVE INGREDIENT3NXW29V3WOEPLERENONE TABLET, FILM COATED [GREENSTONE LLC]10
LACTOSEINACTIVE INGREDIENTJ2B2A4N98GEPLERENONE TABLET, FILM COATED [GREENSTONE LLC]10
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30EPLERENONE TABLET, FILM COATED [GREENSTONE LLC]10
POLYETHYLENE GLYCOLSINACTIVE INGREDIENT3WJQ0SDW1AEPLERENONE TABLET, FILM COATED [GREENSTONE LLC]10
POLYSORBATE 80INACTIVE INGREDIENT6OZP39ZG8HEPLERENONE TABLET, FILM COATED [GREENSTONE LLC]10
SODIUM LAURYL SULFATEINACTIVE INGREDIENT368GB5141JEPLERENONE TABLET, FILM COATED [GREENSTONE LLC]10
TALCINACTIVE INGREDIENT7SEV7J4R1UEPLERENONE TABLET, FILM COATED [GREENSTONE LLC]10
TITANIUM DIOXIDEINACTIVE INGREDIENT15FIX9V2JPEPLERENONE TABLET, FILM COATED [GREENSTONE LLC]10

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
59762-1720EPLERENONE TABLET, FILM COATED [MYLAN PHARMACEUTICALS INC.]23Current NDC, Legacy NDC, 2 package rows20250503_6d988699-95c2-46b9-8266-23fe7016f33b.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
InspraEPLERENONEViatris Specialty LLC1a52bedc-8e2c-4116-a296-a87770676b4a2025-06-23Warnings, Adverse reactionsExact identifier
application applno (NDA): 021437
application number: NDA021437
EplerenoneEPLERENONEMylan Pharmaceuticals Inc.4286699b-2320-4d3d-831c-32085f36fb672025-06-23Warnings, Adverse reactionsExact identifier
application applno (NDA): 021437
application number: NDA021437
EplerenoneEPLERENONEMylan Pharmaceuticals Inc.6d988699-95c2-46b9-8266-23fe7016f33b2020-08-27Warnings, Adverse reactionsExact identifier
application applno (NDA): 021437
application number: NDA021437
ndc (product): 59762-1720

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
351256eplerenone 25 MG Oral TabletPSN6d988699-95c2-46b9-8266-23fe7016f33b25
351257eplerenone 50 MG Oral TabletPSN6d988699-95c2-46b9-8266-23fe7016f33b25
351256eplerenone 25 MG Oral TabletSCD6d988699-95c2-46b9-8266-23fe7016f33b25
351257eplerenone 50 MG Oral TabletSCD6d988699-95c2-46b9-8266-23fe7016f33b25

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
59762-1720-15976217200130 TABLET, FILM COATED in 1 BOTTLE (59762-1720-1) 2002-09-272026-08-31NoNoCurrent
59762-1720-25976217200290 TABLET, FILM COATED in 1 BOTTLE (59762-1720-2) 2002-09-272026-08-31NoNoCurrent