Aplicare Povidone-Iodine

Product NDC: 52380-1905
11-digit product format: 523801905
Labeler code: 52380
Product ID: 52380-1905_5a86eb3c-9bed-842f-e063-6294a90adff3
Type: HUMAN OTC DRUG
Nonproprietary name: Povidone-Iodine
Dosage form: SOLUTION
Route: TOPICAL
Labeler: Aplicare Products, LLC
Application: 505G(a)(3)
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 1998-09-01
Substance: POVIDONE-IODINE
Active strength: 10 mg/mL
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 6 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded package	package	52380-1905	52380-1905-2	D	Discontinued by firm	2026-10-05
excluded package	package	52380-1905	52380-1905-4	D	Discontinued by firm	2026-10-05
excluded package	package	52380-1905	52380-1905-6	D	Discontinued by firm	2026-10-05
excluded package	package	52380-1905	52380-1905-7	D	Discontinued by firm	2026-10-05
excluded package	package	52380-1905	52380-1905-8	D	Discontinued by firm	2026-10-05
excluded package	package	52380-1905	52380-1905-9	D	Discontinued by firm	2026-10-05

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 2 · 72 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Package NDC, Snapshot table
Captured / source date	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	52380-1905-9	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	52380-1905-8	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	52380-1905-6	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	52380-1905-7	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	52380-1905-2	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	52380-1905-4	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	52380-1905-9	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	52380-1905-8	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	52380-1905-6	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	52380-1905-7	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	52380-1905-2	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	52380-1905-4	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	52380-1905-9	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	52380-1905-8	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	52380-1905-6	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	52380-1905-7	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	52380-1905-2	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	52380-1905-4	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	52380-1905-9	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	52380-1905-8	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	52380-1905-6	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	52380-1905-7	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	52380-1905-2	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	52380-1905-4	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	52380-1905-9	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	52380-1905-8	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	52380-1905-6	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	52380-1905-7	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	52380-1905-2	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	52380-1905-4	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	52380-1905-9	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	52380-1905-8	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	52380-1905-6	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	52380-1905-7	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	52380-1905-2	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	52380-1905-4	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	52380-1905-9	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	52380-1905-8	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	52380-1905-6	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	52380-1905-7	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	52380-1905-2	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	52380-1905-4	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	52380-1905-9	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	52380-1905-8	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	52380-1905-6	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	52380-1905-7	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	52380-1905-2	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	52380-1905-4	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	52380-1905-9	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	52380-1905-8	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	52380-1905-6	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	52380-1905-7	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	52380-1905-2	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	52380-1905-4	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	52380-1905-9	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	52380-1905-8	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	52380-1905-6	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	52380-1905-7	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	52380-1905-2	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	52380-1905-4	`ad56d346431e…`	`cc804d4bbf1e…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Aplicare Povidone-Iodine
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
POVIDONE-IODINE	10 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
85H0HZU99M	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
312564	Internal RxNorm lookup
617973	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
7302a2f8-a600-4200-bc4e-309e4c190fe5	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
5f30b278-5791-4113-8781-878a9221ef8a	Product name	2	20230125
2a70c781-a755-4d76-b20a-a958acfbdcdc	Product name	2	20190619
304592ef-4a8a-4c22-8e8c-af73aa3d60e5	Product name	1	20180703
ac0821a1-ce75-4ea7-880a-59eecaecdf22	Product name	1	20180703
db5dc4f9-b907-46f6-8fb7-babcf04bbe5c	Product name	1	20180619
41e9d6cf-3ed7-4c44-a57e-0685058d0896	Product name	1	20170824
5e652c92-68fd-426b-b0e7-5fc64e0b9f99	Product name	1	20170309
ddc0c11a-bba8-408f-b3c7-c4828b4bcc8c	Product name	1	20150421

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
52380-1905-0	Aplicare Povidone-Iodine	60 mL in 1 BOTTLE, SPRAY	SOLUTION	60	18
52380-1905-2	Aplicare Povidone-Iodine	60 mL in 1 BOTTLE	SOLUTION	60	18
52380-1905-3	Aplicare Povidone-Iodine	90 mL in 1 BOTTLE	SOLUTION	90	18
52380-1905-4	Aplicare Povidone-Iodine	120 mL in 1 BOTTLE	SOLUTION	120	18
52380-1905-6	Aplicare Povidone-Iodine	480 mL in 1 BOTTLE	SOLUTION	480	18
52380-1905-7	Aplicare Povidone-Iodine	960 mL in 1 BOTTLE	SOLUTION	960	18
52380-1905-8	Aplicare Povidone-Iodine	240 mL in 1 BOTTLE	SOLUTION	240	18
52380-1905-9	Aplicare Povidone-Iodine	3800 mL in 1 BOTTLE	SOLUTION	3800	18

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
52380-1905-0	ML - Milliliter	52380-1905	712f4860-73a5-4627-acea-455ac394f12f	1	2012-07-24
52380-1905-2	ML - Milliliter	52380-1905	865096b9-06c0-4359-8597-be462a1cfe22	1	2012-07-24
52380-1905-4	ML - Milliliter	52380-1905	1f55cb39-ca3a-4ea3-9c93-46d3b7e8f6ce	1	2012-07-24
52380-1905-6	ML - Milliliter	52380-1905	c5cf32e5-a122-4909-938d-a2be489b2b81	1	2012-07-24
52380-1905-7	ML - Milliliter	52380-1905	f43064fa-189c-446f-8ec6-2b2620d74e29	1	2012-07-24
52380-1905-8	ML - Milliliter	52380-1905	fa272fa7-ef75-49e7-9148-7ac22bd1cb51	1	2012-07-24
52380-1905-9	ML - Milliliter	52380-1905	65df94e9-1ee3-42e9-91ae-04b9bf544a73	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
POVIDONE-IODINE	ACTIVE INGREDIENT	85H0HZU99M	APLICARE POVIDONE-IODINE (POVIDONE-IODINE) SOLUTION [APLICARE, INC.]	6
IODINE	ACTIVE MOIETY	9679TC07X4	APLICARE POVIDONE-IODINE (POVIDONE-IODINE) SOLUTION [APLICARE, INC.]	6
CITRIC ACID MONOHYDRATE	INACTIVE INGREDIENT	2968PHW8QP	APLICARE POVIDONE-IODINE (POVIDONE-IODINE) SOLUTION [APLICARE, INC.]	6
NONOXYNOL-9	INACTIVE INGREDIENT	48Q180SH9T	APLICARE POVIDONE-IODINE (POVIDONE-IODINE) SOLUTION [APLICARE, INC.]	6
SODIUM HYDROXIDE	INACTIVE INGREDIENT	55X04QC32I	APLICARE POVIDONE-IODINE (POVIDONE-IODINE) SOLUTION [APLICARE, INC.]	6
SODIUM PHOSPHATE, DIBASIC	INACTIVE INGREDIENT	GR686LBA74	APLICARE POVIDONE-IODINE (POVIDONE-IODINE) SOLUTION [APLICARE, INC.]	6
WATER	INACTIVE INGREDIENT	059QF0KO0R	APLICARE POVIDONE-IODINE (POVIDONE-IODINE) SOLUTION [APLICARE, INC.]	6

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
52380-1905	APLICARE POVIDONE-IODINE (POVIDONE-IODINE) SOLUTION [APLICARE PRODUCTS, LLC]	17	Current NDC, Legacy NDC, 8 package rows	20240110_7302a2f8-a600-4200-bc4e-309e4c190fe5.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Aplicare Povidone-Iodine	POVIDONE-IODINE	Aplicare Products, LLC	7302a2f8-a600-4200-bc4e-309e4c190fe5	2026-09-02	Warnings	Exact identifier ndc (product): 52380-1905

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
85H0HZU99M	POVIDONE-IODINE	25655-41-8	POVIDONE-IODINE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
312564	povidone-iodine 10 % Topical Solution	PSN	7302a2f8-a600-4200-bc4e-309e4c190fe5	18
617973	povidone-iodine 10 % Topical Spray	PSN	7302a2f8-a600-4200-bc4e-309e4c190fe5	18
312564	povidone-iodine 100 MG/ML Topical Solution	SCD	7302a2f8-a600-4200-bc4e-309e4c190fe5	18
617973	povidone-iodine 100 MG/ML Topical Spray	SCD	7302a2f8-a600-4200-bc4e-309e4c190fe5	18
312564	povidone-iodine 10 % (titratable iodine 1 % ) Topical Solution	SY	7302a2f8-a600-4200-bc4e-309e4c190fe5	18
617973	povidone-iodine 10 % Topical Spray	SY	7302a2f8-a600-4200-bc4e-309e4c190fe5	18

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
52380-1905-0	52380190500	60 mL in 1 BOTTLE, SPRAY (52380-1905-0)	60 ml	1998-09-01	0000-00-00	No	No	Current
52380-1905-2	52380190502	60 mL in 1 BOTTLE (52380-1905-2)	60 ml	1998-09-01	2022-11-06	No	No	Current
52380-1905-3	52380190503	90 mL in 1 BOTTLE (52380-1905-3)	90 ml	1998-09-01	0000-00-00	No	No	Current
52380-1905-4	52380190504	120 mL in 1 BOTTLE (52380-1905-4)	120 ml	1998-09-01	2022-11-06	No	No	Current
52380-1905-6	52380190506	480 mL in 1 BOTTLE (52380-1905-6)	480 ml	1998-09-01	2022-11-06	No	No	Current
52380-1905-7	52380190507	960 mL in 1 BOTTLE (52380-1905-7)	960 ml	1998-09-01	0000-00-00	No	No	Current
52380-1905-8	52380190508	240 mL in 1 BOTTLE (52380-1905-8)	240 ml	1998-09-01	2022-06-01	No	No	Current
52380-1905-9	52380190509	3800 mL in 1 BOTTLE (52380-1905-9)	3800 ml	1998-09-01	2022-06-01	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
1905 10% PVP-I Scrub, Non-Sterile	Aplicare Products, LLC \| Medline Industries, LP	2026-09-02	HUMAN OTC DRUG LABEL	20