venlafaxine

Product NDC
52427-632
11-digit product format
524270632
Labeler code
52427
Product ID
52427-632_1b0762be-0db0-b997-b76b-b212a496f82c
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
venlafaxine
Dosage form
TABLET, EXTENDED RELEASE
Route
ORAL
Labeler
Almatica Pharma LLC
Application
NDA215429
Marketing category
NDA
Marketing start
2022-06-30
Substance
VENLAFAXINE BESYLATE MONOHYDRATE
Active strength
112.5 mg/1
Pharmacologic classes
Norepinephrine Uptake Inhibitors [MoA], Serotonin Uptake Inhibitors [MoA], Serotonin and Norepinephrine Reuptake Inhibitor [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N215429-001VENLAFAXINE BESYLATEVENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29

Orange Book patents#

Current patent rows page 1 of 1 · 1 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N215429-00177763582028-05-16Drug product2022-07-20

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-2931067a03dcf5…
2025-08-23 18:47 UTC2025-08N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-296a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-2903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-292680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-295bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-2979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-291e350fbaab3a…
2024-05-31 18:47 UTC2024-05N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-298072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-296a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-291c564ffb4f44…
2023-12-20 04:57 UTC2023-12N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-299b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-293f0d92c62455…
2023-05-13 08:27 UTC2023-05N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29053a50430f4f…
2023-01-26 05:58 UTC2023-01N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-293bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-293a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N215429-001VENLAFAXINE BESYLATEEQ 112.5MG BASETABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-29a50c72e98297…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N215429-00177763582028-05-16Drug product2022-07-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215429-00177763582028-05-16Drug product2022-07-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08N215429-00177763582028-05-16Drug product2022-07-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215429-00177763582028-05-16Drug product2022-07-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215429-00177763582028-05-16Drug product2022-07-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215429-00177763582028-05-16Drug product2022-07-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215429-00177763582028-05-16Drug product2022-07-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215429-00177763582028-05-16Drug product2022-07-205bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215429-00177763582028-05-16Drug product2022-07-20d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N215429-00177763582028-05-16Drug product2022-07-20d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215429-00177763582028-05-16Drug product2022-07-2079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215429-00177763582028-05-16Drug product2022-07-20301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215429-00177763582028-05-16Drug product2022-07-201e350fbaab3a…
2024-05-31 18:47 UTC2024-05N215429-00177763582028-05-16Drug product2022-07-208072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N215429-00177763582028-05-16Drug product2022-07-206a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N215429-00177763582028-05-16Drug product2022-07-201c564ffb4f44…
2023-12-20 04:57 UTC2023-12N215429-00167170152023-03-27U-451Drug substance, Drug product2022-07-20ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12N215429-00177763582028-05-16Drug product2022-07-20ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N215429-00167170152023-03-27U-451Drug substance, Drug product2022-07-20a72a2bbeb626…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N215429-00177763582028-05-16Drug product2022-07-20a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N215429-00167170152023-03-27U-451Drug substance, Drug product2022-07-209b2671bbb829…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N215429-00177763582028-05-16Drug product2022-07-209b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N215429-00167170152023-03-27U-451Drug substance, Drug product2022-07-20a67488948f0b…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N215429-00177763582028-05-16Drug product2022-07-20a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N215429-00167170152023-03-27U-451Drug substance, Drug product2022-07-203f0d92c62455…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N215429-00177763582028-05-16Drug product2022-07-203f0d92c62455…
2023-05-13 08:27 UTC2023-05N215429-00167170152023-03-27U-451Drug substance, Drug product2022-07-20053a50430f4f…
2023-05-13 08:27 UTC2023-05N215429-00177763582028-05-16Drug product2022-07-20053a50430f4f…
2023-01-26 05:58 UTC2023-01N215429-00167170152023-03-27U-451Drug substance, Drug product2022-07-203bdfa0b2c4d7…
2023-01-26 05:58 UTC2023-01N215429-00177763582028-05-16Drug product2022-07-203bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N215429-00167170152023-03-27U-451Drug substance, Drug product2022-07-203a93d1ddd44b…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N215429-00177763582028-05-16Drug product2022-07-203a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N215429-00167170152023-03-27U-451Drug substance, Drug product2022-07-20f41ea6bd6efb…
2022-10-28 04:53 UTC2022-10N215429-00177763582028-05-16Drug product2022-07-20f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N215429-00167170152023-03-27U-451Drug substance, Drug product2022-07-20e64feba35796…
2022-09-29 23:25 UTC2022-09N215429-00177763582028-05-16Drug product2022-07-20e64feba35796…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N215429-00177763582028-05-16Drug product2022-07-20a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
venlafaxine
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
VENLAFAXINE BESYLATE MONOHYDRATE112.5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
18XP3YT5NHInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2605950Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
e81a2daf-b8b2-7c05-b532-bc775700b100Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
17db3736-056c-48b9-b0f4-00fccabb14e6Product name520251118
7be8b949-f2c0-bdd8-e89d-8af92c1b2eadProduct name920250224
b1435b59-059c-404b-a587-53656bf80e17Product name120230314
6005cd75-f7b1-d6be-3cb5-4bd30d5c4617Product name320190314

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
52427-632-30venlafaxine30 in 1 BOTTLETABLET, EXTENDED RELEASE304

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
52427-632-30EA - Each52427-63249d4e14b-5e36-479a-beeb-095e31d5214712022-08-04

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
52427-632VENLAFAXINE TABLET, EXTENDED RELEASE [ALMATICA PHARMA LLC]3Current NDC, Legacy NDC, 1 package rows20241011_e81a2daf-b8b2-7c05-b532-bc775700b100.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
venlafaxineVENLAFAXINEAlmatica Pharma LLCe81a2daf-b8b2-7c05-b532-bc775700b1002025-10-09Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 215429
application number: NDA215429
ndc (product): 52427-632

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2605950venlafaxine 112.5 MG 24HR Extended Release Oral TabletPSNe81a2daf-b8b2-7c05-b532-bc775700b1004
260595024 HR venlafaxine 112.5 MG Extended Release Oral TabletSCDe81a2daf-b8b2-7c05-b532-bc775700b1004
2605950venlafaxine 112.5 MG (as venlafaxine besylate monohydrate 183.95 MG) 24 HR Extended Release Oral TabletSYe81a2daf-b8b2-7c05-b532-bc775700b1004

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
52427-632-305242706323030 TABLET, EXTENDED RELEASE in 1 BOTTLE (52427-632-30) 2022-08-010000-00-00NoNoCurrent