Lomustine

Product NDC
52536-342
11-digit product format
525360342
Labeler code
52536
Product ID
52536-342_934ec2f1-8c3f-4978-b712-33e98c4295a5
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
lomustine
Dosage form
CAPSULE, GELATIN COATED
Route
ORAL
Labeler
Wilshire Pharmaceuticals, Inc.
Application
NDA017588
Marketing category
NDA
Marketing start
2026-04-15
Substance
LOMUSTINE
Active strength
100 mg/1
Pharmacologic classes
Alkylating Activity [MoA], Alkylating Drug [EPC]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 4 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N017588-001GLEOSTINELOMUSTINE10MGCAPSULE / ORALABRLD, Approved before 1982
N017588-002GLEOSTINELOMUSTINE40MGCAPSULE / ORALABRLD, RS, Approved before 1982
N017588-003GLEOSTINELOMUSTINE100MGCAPSULE / ORALABRLD, Approved before 1982
N017588-004GLEOSTINELOMUSTINE5MGCAPSULE / ORALRLD2014-12-19

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
N017588-001AB
N017588-002AB
N017588-003AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-01 22:54:322026-06N017588-001GLEOSTINE10MGCAPSULE / ORALABRLD, Approved before 1982a50c72e98297…
2026-08-01 22:54:322026-06N017588-002GLEOSTINE40MGCAPSULE / ORALABRLD, RS, Approved before 1982a50c72e98297…
2026-08-01 22:54:322026-06N017588-003GLEOSTINE100MGCAPSULE / ORALABRLD, Approved before 1982a50c72e98297…
2026-08-01 22:54:322026-06N017588-004GLEOSTINE5MGCAPSULE / ORALRLD2014-12-19a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-01 22:54:322026-06N017588-001AB1a50c72e98297…
2026-08-01 22:54:322026-06N017588-002AB1a50c72e98297…
2026-08-01 22:54:322026-06N017588-003AB1a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
LomustineLOMUSTINEWilshire Pharmaceuticals, Inc.3c3637fc-4499-4331-a3c4-6969fc86704e2026-02-12Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 017588
application number: NDA017588
ndc (product): 52536-342
GleostineLOMUSTINEAzurity Pharmaceuticals, Inc.3529fe2f-3c23-4862-bb20-b480269570822025-09-25Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 017588
application number: NDA017588
GleostineLOMUSTINENextSource Biotechnology, LLC7f77526b-4c40-409c-82ea-d0f934d89cc22024-01-23Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 017588
application number: NDA017588

Additional Listing Data#

Finished product
Yes
Brand name base
Lomustine
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LOMUSTINE100 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
7BRF0Z81KGInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
197894Internal RxNorm lookup
197895Internal RxNorm lookup
197896Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
3c3637fc-4499-4331-a3c4-6969fc86704eAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
a62a50ac-1535-4461-9768-8ae703e2e9fbProduct name120210525
9514609b-a2a9-f8ec-6ba6-3f8e5ee89877Product name120140508
bc07ef78-e82d-0c19-31f4-31f263780582Product name120140508
d20364c4-b9df-9129-4e74-fd201b79f7c5Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
52536-342-05Lomustine5 in 1 BOTTLECAPSULE, GELATIN COATED52
52536-342-05Lomustine1 in 1 CARTONCAPSULE, GELATIN COATED12

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
197894lomustine 10 MG Oral CapsulePSN3c3637fc-4499-4331-a3c4-6969fc86704e2
197895lomustine 100 MG Oral CapsulePSN3c3637fc-4499-4331-a3c4-6969fc86704e2
197896lomustine 40 MG Oral CapsulePSN3c3637fc-4499-4331-a3c4-6969fc86704e2
197894lomustine 10 MG Oral CapsuleSCD3c3637fc-4499-4331-a3c4-6969fc86704e2
197895lomustine 100 MG Oral CapsuleSCD3c3637fc-4499-4331-a3c4-6969fc86704e2
197896lomustine 40 MG Oral CapsuleSCD3c3637fc-4499-4331-a3c4-6969fc86704e2

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
52536-342-05525360342051 BOTTLE in 1 CARTON (52536-342-05) / 5 CAPSULE, GELATIN COATED in 1 BOTTLE1 bottle2026-04-15NoNoCurrent