Verapamil Hydrochloride

Product NDC: 52536-486
11-digit product format: 525360486
Labeler code: 52536
Product ID: 52536-486_27ea8c5d-0f1f-0e1c-e063-6294a90a44e5
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: Verapamil Hydrochloride
Dosage form: CAPSULE, EXTENDED RELEASE
Route: ORAL
Labeler: Wilshire Pharmaceuticals, Inc.
Application: NDA020943
Marketing category: NDA AUTHORIZED GENERIC
Marketing start: 2024-11-26
Substance: VERAPAMIL HYDROCHLORIDE
Active strength: 200 mg/1
Pharmacologic classes: Calcium Channel Antagonists [MoA], Calcium Channel Blocker [EPC], Cytochrome P450 3A Inhibitors [MoA], Cytochrome P450 3A4 Inhibitors [MoA], P-Glycoprotein Inhibitors [MoA]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	RLD / RS	Approval date
N020943-001	VERELAN PM	VERAPAMIL HYDROCHLORIDE	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25
N020943-002	VERELAN PM	VERAPAMIL HYDROCHLORIDE	200MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25
N020943-003	VERELAN PM	VERAPAMIL HYDROCHLORIDE	300MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD, RS	1998-11-25

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	RLD / RS	Approval date	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N020943-001	VERELAN PM	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N020943-002	VERELAN PM	200MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N020943-003	VERELAN PM	300MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD, RS	1998-11-25	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N020943-001	VERELAN PM	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N020943-002	VERELAN PM	200MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N020943-003	VERELAN PM	300MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD, RS	1998-11-25	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N020943-001	VERELAN PM	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N020943-002	VERELAN PM	200MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N020943-003	VERELAN PM	300MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD, RS	1998-11-25	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N020943-001	VERELAN PM	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N020943-002	VERELAN PM	200MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N020943-003	VERELAN PM	300MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD, RS	1998-11-25	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N020943-001	VERELAN PM	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N020943-002	VERELAN PM	200MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N020943-003	VERELAN PM	300MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD, RS	1998-11-25	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N020943-001	VERELAN PM	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N020943-002	VERELAN PM	200MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N020943-003	VERELAN PM	300MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD, RS	1998-11-25	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N020943-001	VERELAN PM	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N020943-002	VERELAN PM	200MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N020943-003	VERELAN PM	300MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD, RS	1998-11-25	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N020943-001	VERELAN PM	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N020943-002	VERELAN PM	200MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N020943-003	VERELAN PM	300MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD, RS	1998-11-25	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N020943-001	VERELAN PM	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N020943-002	VERELAN PM	200MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N020943-003	VERELAN PM	300MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD, RS	1998-11-25	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N020943-001	VERELAN PM	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N020943-002	VERELAN PM	200MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N020943-003	VERELAN PM	300MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD, RS	1998-11-25	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N020943-001	VERELAN PM	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N020943-002	VERELAN PM	200MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N020943-003	VERELAN PM	300MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD, RS	1998-11-25	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N020943-001	VERELAN PM	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N020943-002	VERELAN PM	200MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N020943-003	VERELAN PM	300MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD, RS	1998-11-25	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N020943-001	VERELAN PM	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N020943-002	VERELAN PM	200MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N020943-003	VERELAN PM	300MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD, RS	1998-11-25	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N020943-001	VERELAN PM	100MG	CAPSULE, EXTENDED RELEASE / ORAL	RLD	1998-11-25	`8072bd15b7f6…`

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2019-12-13 00:20 UTC	2019-12	N020943-001	AB	1	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N020943-002	AB	1	`74a2ff9319b5…`
2019-09-15 20:21 UTC	2019-09	N020943-001	AB	1	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N020943-002	AB	1	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N020943-001	AB	1	`ea99ee380514…`
2019-07-19 19:46 UTC	2019-07	N020943-002	AB	1	`ea99ee380514…`

Additional Listing Data#

Finished product: Yes
Brand name base: Verapamil Hydrochloride
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
VERAPAMIL HYDROCHLORIDE	200 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
V3888OEY5R	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
897584	Internal RxNorm lookup
897590	Internal RxNorm lookup
897596	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
5f665d08-e1e4-422a-88c2-d8834abf9e1a	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
ea1f6fc8-bfc2-4421-a2eb-4e87c7c3e3c4	Product name	2	20230103
33ad674d-d105-6aa5-02fa-95ae4329b8cd	Product name	2	20180809
3279bd6d-5b02-e60b-3857-c853a2deb2dd	Product name	2	20170713
8ebb66e3-d7b3-f1e5-88aa-3369e64bb84a	Product name	1	20140508
940a1faa-2df8-cc65-be37-1b97984b4ea3	Product name	1	20140508
d3b67bc2-0e96-e3ec-06a9-90afcc07bf13	Product name	1	20140508
e2fcd66c-a043-3187-790d-b0342deb1149	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
52536-486-37	Verapamil Hydrochloride	100 in 1 BOTTLE	CAPSULE, EXTENDED RELEASE	100		1

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
52536-486-37	EA - Each	52536-486	b15922b2-785c-4da2-96bd-142c4dfd4d27	1	2025-01-14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
52536-486	VERAPAMIL HYDROCHLORIDE CAPSULE, EXTENDED RELEASE [WILSHIRE PHARMACEUTICALS, INC.]	1	Current NDC, 1 package rows	20241129_5f665d08-e1e4-422a-88c2-d8834abf9e1a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Verapamil Hydrochloride	VERAPAMIL HYDROCHLORIDE	Chartwell RX, LLC	18f6d349-8c5c-4443-ac65-16bf6619ecdc	2025-03-25	Warnings, Adverse reactions	Exact identifier application applno (NDA): 020943 application number: NDA020943
Verapamil Hydrochloride	VERAPAMIL HYDROCHLORIDE	Wilshire Pharmaceuticals, Inc.	5f665d08-e1e4-422a-88c2-d8834abf9e1a	2024-11-27	Warnings, Adverse reactions	Exact identifier application applno (NDA): 020943 application number: NDA020943 ndc (product): 52536-486

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
V3888OEY5R	VERAPAMIL HYDROCHLORIDE	152-11-4	VERAPAMIL HYDROCHLORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
897584	verapamil HCl 100 MG 24HR Extended Release Oral Capsule	PSN	5f665d08-e1e4-422a-88c2-d8834abf9e1a	1
897590	verapamil HCl 200 MG 24HR Extended Release Oral Capsule	PSN	5f665d08-e1e4-422a-88c2-d8834abf9e1a	1
897596	verapamil HCl 300 MG 24HR Extended Release Oral Capsule	PSN	5f665d08-e1e4-422a-88c2-d8834abf9e1a	1
897584	24 HR verapamil hydrochloride 100 MG Extended Release Oral Capsule	SCD	5f665d08-e1e4-422a-88c2-d8834abf9e1a	1
897590	24 HR verapamil hydrochloride 200 MG Extended Release Oral Capsule	SCD	5f665d08-e1e4-422a-88c2-d8834abf9e1a	1
897596	24 HR verapamil hydrochloride 300 MG Extended Release Oral Capsule	SCD	5f665d08-e1e4-422a-88c2-d8834abf9e1a	1
897584	verapamil hydrochloride 100 MG 24 HR Extended Release Oral Capsule	SY	5f665d08-e1e4-422a-88c2-d8834abf9e1a	1
897590	verapamil hydrochloride 200 MG 24 HR Extended Release Oral Capsule	SY	5f665d08-e1e4-422a-88c2-d8834abf9e1a	1
897596	verapamil hydrochloride 300 MG 24 HR Extended Release Oral Capsule	SY	5f665d08-e1e4-422a-88c2-d8834abf9e1a	1

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Sample	Exclude flag	Status
52536-486-37	52536048637	100 CAPSULE, EXTENDED RELEASE in 1 BOTTLE (52536-486-37)	2024-11-26	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Verapamil Hydrochloride	Wilshire Pharmaceuticals, Inc.	2024-11-27	HUMAN PRESCRIPTION DRUG LABEL	1