ActivICE

Product NDC: 53329-992
11-digit product format: 533290992
Labeler code: 53329
Product ID: 53329-992_4f5db354-ecdb-3529-e063-6394a90ae094
Type: HUMAN OTC DRUG
Nonproprietary name: menthol
Dosage form: LIQUID
Route: TOPICAL
Labeler: Medline Industries, LP
Application: M017
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2019-03-04
Substance: MENTHOL
Active strength: 80 g/1000g
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: ActivICE
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
MENTHOL	80 g/1000g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
L7T10EIP3A	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
727162	Internal RxNorm lookup
2264041	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
8465b443-abe9-78fb-e053-2a91aa0ac1d8	Available on FDA.report

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
53329-992-69	ActivICE	85 g in 1 BOTTLE, PLASTIC	LIQUID	85		7

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
53329-992	ACTIVICE (MENTHOL) LIQUID [MEDLINE INDUSTRIES, LP]	6	Current NDC, Legacy NDC, 1 package rows	20241215_8465b443-abe9-78fb-e053-2a91aa0ac1d8.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 37 of 153 · 3,057 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
PAIN RELIEF PATCHES	LIDOCAINE	WALMART STORES INC	b82cfe42-f521-4784-8c60-98481524c5ec	2026-01-29	Warnings	Exact identifier application number: M017
Equate Pain Relief Patch Camphor/Menthol/Salicylate	CAMPHOR, MENTHOL, METHYL SALICYLATE	Walmart Stores Inc	b869848c-21e2-5ca2-e053-2995a90a86f2	2026-01-29	Warnings	Exact identifier application number: M017
HEATING PAIN RELIEF	METHYL SALICYLATE, MENTHOL	SUNSET NOVELTIES, INC	498cd2aa-ee59-67b5-e063-6294a90ac242	2026-01-29	Warnings	Exact identifier application number: M017
COOLING PAIN RELIEF	MENTHOL, CAMPHOR	SUNSET NOVELTIES, INC	498d76d8-788b-4cc7-e063-6294a90a1696	2026-01-29	Warnings	Exact identifier application number: M017
MQUPIN Lidocaine Gel-Patch	LIDOCAINE GEL-PATCH	Zhengzhou Miaoqi Medical Technology Co., Ltd.	49703717-69a6-e480-e063-6394a90ac69c	2026-01-28	Warnings	Exact identifier application number: M017
MQXUNMI LIDOCAINE Pain Relief Patch	LIDOCAINE PAIN RELIEF PATCH	Zhengzhou Miaoqi Medical Technology Co., Ltd.	49706db7-bacd-190f-e063-6394a90a3a8e	2026-01-28	Warnings	Exact identifier application number: M017
Joint and Muscle Relief Topical Analgesic	MENTHOL	Smart Cookie Solutions	1ecf56b1-ffcb-486f-9fdd-d4dc92aefc1d	2026-01-28	Warnings	Exact identifier application number: M017
VonaFlex Effective Pain Relief Topical Analgesic	LIDOCAINE HYDROCHLORIDE	OPTIMAL LABORATORIES, LLC	0901244a-7d41-413a-b424-92a807532f28	2026-01-28	Warnings	Exact identifier application number: M017
Lidocaine Pain Relief Gel Patch	LIDOCAINE PAIN RELIEF	Dynarex	960e4240-cd09-2560-e053-2a95a90a7bcf	2026-01-28	Warnings	Exact identifier application number: M017
ALOE ICE SUNBURN RELIEF	LIDOCAINE HYDROCHLORIDE	Aloe Care International, LLC	56866fa8-052e-497c-a954-978d7d628949	2026-01-28	Warnings	Exact identifier application number: M017
Walgreens Original Strength Anti Itch	DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE	Walgreen Company	a6a49dbb-74c7-47ca-88f2-3bb3d9acf914	2026-01-28	Warnings	Exact identifier application number: M017
Flobow QUIT SMOKING Nicotine	NICOTINE18% MENTHOL 0.3% QUIT SMOKING NICOTINE	Jiangxi Yudexi Pharmaceutical Co., LTD	495b10ce-3d2d-1aa4-e063-6294a90a4f35	2026-01-27	Warnings	Exact identifier application number: M017
PAIN	REUSEABLE PAIN	Shenzhen Mengyue Technology Co., Ltd.	44e058fc-e1c0-742b-e063-6294a90ad225	2026-01-27	Warnings	Exact identifier application number: M017
HealthWise Pain Relieving Cream Lavender	MENTHOL	Veridian Healthcare	495eb6e9-69da-f7b6-e063-6294a90accee	2026-01-27	Warnings	Exact identifier application number: M017
HealthWise Pain Relieving Cream	MENTHOL	Veridian Healthcare	49548ab2-267e-1e2a-e063-6394a90ab391	2026-01-27	Warnings	Exact identifier application number: M017
Itch Relief	DIPHENHYDRAMINE HCL	Wal-Mart Stores, Inc.	03feaaef-7401-d464-e063-6294a90a2b2d	2026-01-27	Warnings	Exact identifier application number: M017
Hydrocortisone with Aloe	HYDROCORTISONE	STRATEGIC SOURCING SERVICES LLC	4a113699-1eb7-49b8-8cdf-2ad57db89b81	2026-01-27	Warnings	Exact identifier application number: M017
Healthy Back Institute Rub On Relief	ANALGESIC	Fullstack Fulfillment	284c29a3-5722-ce70-e063-6394a90a7fa0	2026-01-26	Warnings	Exact identifier application number: M017
Velocx for Joint and Muscle Pain Roll-On Applicator	MENTHOL, METHYL SALICYLATE	JMAD Consulting LLC, dba JMAD Labs	dbf3eaa3-d85e-46b1-b4a5-a87ba4dc5d21	2026-01-26	Warnings	Exact identifier application number: M017
CAPSAICIN HEAT PATCHES BACK AND LARGE AREAS	CAPSAICIN	Meijer Distribution Inc	9b91658f-c15f-4222-bbd9-881b29de3b6e	2026-01-26	Warnings	Exact identifier application number: M017

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
2264041	ActivICE 8 % Topical Solution	PSN	8465b443-abe9-78fb-e053-2a91aa0ac1d8	7
727162	menthol 8 % Topical Solution	PSN	8465b443-abe9-78fb-e053-2a91aa0ac1d8	7
2264041	menthol 80 MG/ML Topical Solution [ActivICE]	SBD	8465b443-abe9-78fb-e053-2a91aa0ac1d8	7
727162	menthol 80 MG/ML Topical Solution	SCD	8465b443-abe9-78fb-e053-2a91aa0ac1d8	7
2264041	ActivICE 8 % Topical Solution	SY	8465b443-abe9-78fb-e053-2a91aa0ac1d8	7
2264041	ActivICE 80 MG/ML Topical Solution	SY	8465b443-abe9-78fb-e053-2a91aa0ac1d8	7
727162	menthol 8 % Topical Solution	SY	8465b443-abe9-78fb-e053-2a91aa0ac1d8	7

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
53329-992-69	53329099269	85 g in 1 BOTTLE, PLASTIC (53329-992-69)	85 g	2019-03-04	0000-00-00	No	No	Current