Memantine hydrochloride

Product NDC
53746-173
11-digit product format
537460173
Labeler code
53746
Product ID
53746-173_cf08de43-a887-40f3-a074-57ecc8d3093a
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Memantine
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Amneal Pharmaceuticals of New York LLC
Application
ANDA090041
Marketing category
ANDA
Marketing start
2015-04-30
Substance
MEMANTINE HYDROCHLORIDE
Active strength
5 mg/1
Pharmacologic classes
N-methyl-D-aspartate Receptor Antagonist [EPC], NMDA Receptor Antagonists [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A090041-001MEMANTINE HYDROCHLORIDEMEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-10
A090041-002MEMANTINE HYDROCHLORIDEMEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-10

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A090041-001AB
A090041-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-10011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-1031067a03dcf5…
2025-08-23 18:47 UTC2025-08A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-106a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-10fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-10b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-10b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-1003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-1003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-102680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-102680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-105bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-105bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-10d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-10d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-10d06236e962d9…
2024-10-29 15:01 UTC2024-10A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-10d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-1079d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-1079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-10301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-10301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-101e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-101e350fbaab3a…
2024-05-31 18:47 UTC2024-05A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-108072bd15b7f6…
2024-05-31 18:47 UTC2024-05A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-108072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-105c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-105c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-105d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-105d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-104b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-104b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-1074a2ff9319b5…
2019-12-13 00:20 UTC2019-12A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-1074a2ff9319b5…
2022-03-09 01:35 UTC2022-03A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-10bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-10bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A090041-001MEMANTINE HYDROCHLORIDE5MGTABLET / ORALAB2015-04-10782e0a99824c…
2021-12-28 21:50 UTC2021-12A090041-002MEMANTINE HYDROCHLORIDE10MGTABLET / ORALAB2015-04-10782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A090041-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A090041-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090041-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090041-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A090041-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A090041-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090041-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090041-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090041-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090041-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090041-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090041-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090041-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090041-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090041-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090041-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090041-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090041-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A090041-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A090041-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090041-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090041-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090041-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090041-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090041-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090041-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A090041-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A090041-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090041-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090041-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A090041-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A090041-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A090041-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A090041-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A090041-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A090041-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A090041-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A090041-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A090041-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12A090041-002AB1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
Memantine hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
MEMANTINE HYDROCHLORIDE5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
JY0WD0UA60Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
996561Internal RxNorm lookup
996571Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
054069b5-7aac-4106-821f-ebf7fd531b4fAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
94db636e-a074-45fd-8e8d-331920a99436Product name420250103
941773f8-a40e-0684-da08-ff9a143e6368Product name720231219
594e2c86-3079-4e6e-96c9-48f7a8afc78dProduct name120230718
5b597f00-4538-4686-aa4e-3c60ed3788c8Product name220210511
1836e79a-a4d1-4087-2f2e-f878e8a1fef2Product name920151209

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
53746-173-10Memantine hydrochloride1000 in 1 BOTTLETABLET, FILM COATED100019
53746-173-30Memantine hydrochloride30 in 1 BOTTLETABLET, FILM COATED3019
53746-173-60Memantine hydrochloride60 in 1 BOTTLETABLET, FILM COATED6019

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
53746-173-60EA - Each53746-17381cfcf8f-d237-4667-8c14-d2f5a47a6d0f12015-08-04

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
MEMANTINE HYDROCHLORIDEACTIVE INGREDIENTJY0WD0UA60MEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9
MEMANTINEACTIVE MOIETYW8O17SJF3TMEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61UMEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9
CROSCARMELLOSE SODIUMINACTIVE INGREDIENTM28OL1HH48MEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9
D&C YELLOW NO. 10INACTIVE INGREDIENT35SW5USQ3GMEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9
FD&C BLUE NO. 2INACTIVE INGREDIENTL06K8R7DQKMEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9
FD&C YELLOW NO. 6INACTIVE INGREDIENTH77VEI93A8MEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9
FERRIC OXIDE YELLOWINACTIVE INGREDIENTEX438O2MRTMEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9
FERROSOFERRIC OXIDEINACTIVE INGREDIENTXM0M87F357MEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30MEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9
POLYETHYLENE GLYCOLSINACTIVE INGREDIENT3WJQ0SDW1AMEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9
POLYVINYL ALCOHOLINACTIVE INGREDIENT532B59J990MEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9
SILICON DIOXIDEINACTIVE INGREDIENTETJ7Z6XBU4MEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9
TALCINACTIVE INGREDIENT7SEV7J4R1UMEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9
TITANIUM DIOXIDEINACTIVE INGREDIENT15FIX9V2JPMEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK, LLC]9

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
53746-173MEMANTINE HYDROCHLORIDE (MEMANTINE) TABLET, FILM COATED [AMNEAL PHARMACEUTICALS OF NEW YORK LLC]19Current NDC, Legacy NDC, 3 package rows20231128_054069b5-7aac-4106-821f-ebf7fd531b4f.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
memantine hydrochlorideMEMANTINEAmneal Pharmaceuticals LLCf73e0df0-4af4-42f1-bde6-3cccb47ca3782025-12-20Warnings, Adverse reactionsExact identifier
application applno (ANDA): 090041
application number: ANDA090041
Memantine hydrochlorideMEMANTINEAmneal Pharmaceuticals of New York LLC054069b5-7aac-4106-821f-ebf7fd531b4f2023-08-17Warnings, Adverse reactionsExact identifier
application applno (ANDA): 090041
application number: ANDA090041
ndc (product): 53746-173

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
996561memantine HCl 10 MG Oral TabletPSN054069b5-7aac-4106-821f-ebf7fd531b4f19
996571memantine HCl 5 MG Oral TabletPSN054069b5-7aac-4106-821f-ebf7fd531b4f19
996561memantine hydrochloride 10 MG Oral TabletSCD054069b5-7aac-4106-821f-ebf7fd531b4f19
996571memantine hydrochloride 5 MG Oral TabletSCD054069b5-7aac-4106-821f-ebf7fd531b4f19

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
53746-173-10537460173101000 TABLET, FILM COATED in 1 BOTTLE (53746-173-10) 2015-04-300000-00-00NoNoCurrent
53746-173-305374601733030 TABLET, FILM COATED in 1 BOTTLE (53746-173-30) 2015-04-300000-00-00NoNoCurrent
53746-173-605374601736060 TABLET, FILM COATED in 1 BOTTLE (53746-173-60) 2015-04-300000-00-00NoNoCurrent