Acetaminophen and Ibuprofen

Product NDC
53943-034
11-digit product format
539430034
Labeler code
53943
Product ID
53943-034_45c4564c-48b1-71b0-e063-6294a90a4180
Type
HUMAN OTC DRUG
Nonproprietary name
Acetaminophen and Ibuprofen
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
DISCOUNT DRUG MART, INC.
Application
ANDA216999
Marketing category
ANDA
Marketing start
2023-09-08
Substance
ACETAMINOPHEN; IBUPROFEN
Active strength
250; 125 mg/1; mg/1
Pharmacologic classes
Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitors [MoA], Nonsteroidal Anti-inflammatory Drug [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A216999-001ACETAMINOPHEN AND IBUPROFENACETAMINOPHEN; IBUPROFEN250MG;125MGTABLET / ORAL2023-08-01

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-01011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-0131067a03dcf5…
2025-08-23 18:47 UTC2025-08A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-016a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-01fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-01b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-0103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-012680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-015bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-01d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-01d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-0179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-01301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-011e350fbaab3a…
2024-05-31 18:47 UTC2024-05A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-018072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-016a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-011c564ffb4f44…
2023-12-20 04:57 UTC2023-12A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-01ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-01a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-019b2671bbb829…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216999-001ACETAMINOPHEN AND IBUPROFEN250MG;125MGTABLET / ORAL2023-08-01a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Acetaminophen and Ibuprofen
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
IBUPROFEN250 mg/1
ACETAMINOPHEN125 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
WK2XYI10QMInternal UNII lookup
362O9ITL9DInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2387532Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
f9dfeb0e-0d4d-7348-e053-6394a90a8aefAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
1e73f975-1ce7-705e-2bcf-788b1b5e24baProduct name520251124
16cde546-8deb-4df2-a072-dab5566ede95Product name120231003
f6d1b8d7-3bd1-4248-eddd-b60565c88015Product name420230808
874f4e63-49d2-5150-5d77-052172814ebdProduct name620230105
557673c2-8256-b351-e863-4ec71a5a64b0Product name220160714
dbc9a339-6215-4e94-9546-57a3b34902ceProduct name120160517
61c18d4e-b552-5478-8fc0-df38b93e3100Product name120140508
7b2938c9-7eb7-e312-ae90-f54f4240361eProduct name120140508
997601aa-bb5f-6971-6b90-a21132c12c7bProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
53943-034-76Acetaminophen and Ibuprofen72 in 1 CARTONTABLET, FILM COATED723

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
53943-034ACETAMINOPHEN AND IBUPROFEN TABLET, FILM COATED [DISCOUNT DRUG MART, INC.]2Current NDC, 1 package rows20230910_f9dfeb0e-0d4d-7348-e053-6394a90a8aef.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 12 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Acetaminophen and IbuprofenACETAMINOPHEN AND IBUPROFENCVS Pharmacy52193849-d03a-b61b-e063-6394a90ad2772026-07-20WarningsExact identifier
application applno (ANDA): 216999
application number: ANDA216999
Acetaminophen and IbuprofenACETAMINOPHEN AND IBUPROFENBIONPHARMA INC.4834aa7f-cb0c-ec58-e063-6394a90ae2fc2026-01-12WarningsExact identifier
application applno (ANDA): 216999
application number: ANDA216999
Acetaminophen and IbuprofenACETAMINOPHEN AND IBUPROFENWALGREEN COMPANY2789fdef-2d8e-6247-e063-6394a90a974b2025-12-16WarningsExact identifier
application applno (ANDA): 216999
application number: ANDA216999
Acetaminophen and IbuprofenACETAMINOPHEN AND IBUPROFENDISCOUNT DRUG MART, INC.f9dfeb0e-0d4d-7348-e053-6394a90a8aef2025-12-12WarningsExact identifier
application applno (ANDA): 216999
application number: ANDA216999
ndc (product): 53943-034
Acetaminophen and IbuprofenACETAMINOPHEN AND IBUPROFENBionpharma Inc.04ccc4b2-0cfd-3012-e063-6394a90afa792025-12-12WarningsExact identifier
application applno (ANDA): 216999
application number: ANDA216999
Acetaminophen and IbuprofenACETAMINOPHEN AND IBUPROFENMeijer Distribution Inc2d916b1b-334f-15c7-e063-6294a90ae8b42025-05-19WarningsExact identifier
application applno (ANDA): 216999
application number: ANDA216999
Acetaminophen and IbuprofenACETAMINOPHEN AND IBUPROFENAMERISOURCE BERGEN04dc36e8-4d51-aabe-e063-6294a90a0d532025-05-15WarningsExact identifier
application applno (ANDA): 216999
application number: ANDA216999
Acetaminophen and IbuprofenACETAMINOPHEN AND IBUPROFENAMERISOURCE BERGEN353136b4-884d-baa2-e063-6394a90a89e92025-05-15WarningsExact identifier
application applno (ANDA): 216999
application number: ANDA216999
dual action pain relieverACETAMINOPHEN AND IBUPROFENCHAIN DRUG MARKETING ASSOCIATION INC.2397603c-8d87-2e65-e063-6394a90ab73e2024-10-03WarningsExact identifier
application applno (ANDA): 216999
application number: ANDA216999
dual action pain relieverACETAMINOPHEN AND IBUPROFENCHAIN DRUG MARKETING ASSOCIATION INC.23994b21-cbc2-5a34-e063-6394a90acfdf2024-10-03WarningsExact identifier
application applno (ANDA): 216999
application number: ANDA216999
dual action pain relieverACETAMINOPHEN AND IBUPROFENBionpharma Inc.1f470b1b-81a9-e59c-e063-6394a90a40552024-08-09WarningsExact identifier
application applno (ANDA): 216999
application number: ANDA216999
dual action pain relieverACETAMINOPHEN AND IBUPROFENBionpharma Inc.1f2f8fcf-bf08-2a21-e063-6394a90a9e712024-08-08WarningsExact identifier
application applno (ANDA): 216999
application number: ANDA216999

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2387532acetaminophen 250 MG / ibuprofen 125 MG Oral TabletPSNf9dfeb0e-0d4d-7348-e053-6394a90a8aef3
2387532acetaminophen 250 MG / ibuprofen 125 MG Oral TabletSCDf9dfeb0e-0d4d-7348-e053-6394a90a8aef3
2387532APAP 250 MG / ibuprofen 125 MG Oral TabletSYf9dfeb0e-0d4d-7348-e053-6394a90a8aef3

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
53943-034-765394300347672 TABLET, FILM COATED in 1 CARTON (53943-034-76) 2023-09-08NoNoCurrent