MOTEGRITY

Product NDC
54092-546
11-digit product format
540920546
Labeler code
54092
Product ID
54092-546_1278ace1-66f8-4bd8-8cf0-bd731f936563
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
PRUCALOPRIDE
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Takeda Pharmaceuticals America, Inc.
Application
NDA210166
Marketing category
NDA
Marketing start
2018-12-14
Substance
PRUCALOPRIDE SUCCINATE
Active strength
1 mg/1
Pharmacologic classes
Serotonin 4 Receptor Agonists [MoA], Serotonin-4 Receptor Agonist [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N210166-001MOTEGRITYPRUCALOPRIDE SUCCINATEEQ 1MG BASETABLET / ORALABRLD2018-12-14
N210166-002MOTEGRITYPRUCALOPRIDE SUCCINATEEQ 2MG BASETABLET / ORALABRLD, RS2018-12-14

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
N210166-001AB
N210166-002AB

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 2 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N210166-001M-142028-07-10
N210166-002M-142028-07-10

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALABRLD2018-12-14caaa826d4ba7…
2026-08-18 06:07:402026-07N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALABRLD, RS2018-12-14caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALABRLD2018-12-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALABRLD, RS2018-12-14011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALABRLD2018-12-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALABRLD, RS2018-12-1431067a03dcf5…
2025-08-23 18:47 UTC2025-08N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALABRLD2018-12-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALABRLD, RS2018-12-146a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALABRLD2018-12-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALABRLD, RS2018-12-14fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALABRLD2018-12-14b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALABRLD, RS2018-12-14b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALABRLD2018-12-1403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALABRLD, RS2018-12-1403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALRLD2018-12-142680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALRLD, RS2018-12-142680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALRLD2018-12-145bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALRLD, RS2018-12-145bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALRLD2018-12-14d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALRLD, RS2018-12-14d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALRLD2018-12-14d06236e962d9…
2024-10-29 15:01 UTC2024-10N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALRLD, RS2018-12-14d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALRLD2018-12-1479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALRLD, RS2018-12-1479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALRLD2018-12-14301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALRLD, RS2018-12-14301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALRLD2018-12-141e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALRLD, RS2018-12-141e350fbaab3a…
2024-05-31 18:47 UTC2024-05N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALRLD2018-12-148072bd15b7f6…
2024-05-31 18:47 UTC2024-05N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALRLD, RS2018-12-148072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALRLD2018-12-145c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALRLD, RS2018-12-145c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALRLD2018-12-145d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALRLD, RS2018-12-145d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALRLD2018-12-144b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALRLD, RS2018-12-144b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALRLD2018-12-1474a2ff9319b5…
2019-12-13 00:20 UTC2019-12N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALRLD, RS2018-12-1474a2ff9319b5…
2022-03-09 01:35 UTC2022-03N210166-001MOTEGRITYEQ 1MG BASETABLET / ORALRLD2018-12-14bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N210166-002MOTEGRITYEQ 2MG BASETABLET / ORALRLD, RS2018-12-14bb7c543d1eb4…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N210166-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07N210166-002AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N210166-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210166-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210166-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210166-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N210166-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210166-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210166-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210166-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210166-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210166-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210166-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210166-002AB103ed91905a0d…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N210166-001AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N210166-002AB1a50c72e98297…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 56 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-08-18 06:07:402026-07N210166-001M-142028-07-10caaa826d4ba7…
2026-08-18 06:07:402026-07N210166-002M-142028-07-10caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N210166-001M-142028-07-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210166-002M-142028-07-10011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210166-001M-142028-07-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210166-002M-142028-07-1031067a03dcf5…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210166-001NCE2023-12-145c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210166-002NCE2023-12-145c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N210166-001NCE2023-12-145d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N210166-002NCE2023-12-145d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N210166-001NCE2023-12-144b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N210166-002NCE2023-12-144b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N210166-001NCE2023-12-1474a2ff9319b5…
2019-12-13 00:20 UTC2019-12N210166-002NCE2023-12-1474a2ff9319b5…
2022-03-09 01:35 UTC2022-03N210166-001NCE2023-12-14bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N210166-002NCE2023-12-14bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N210166-001NCE2023-12-14782e0a99824c…
2021-12-28 21:50 UTC2021-12N210166-002NCE2023-12-14782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N210166-001NCE2023-12-1487673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N210166-002NCE2023-12-1487673890dc5c…
2021-03-12 10:30 UTC2021-03N210166-001NCE2023-12-145aa47cf7b7d7…
2021-03-12 10:30 UTC2021-03N210166-002NCE2023-12-145aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N210166-001NCE2023-12-148869cabd3fbd…
2020-12-22 03:56 UTC2020-12N210166-002NCE2023-12-148869cabd3fbd…
2020-11-12 02:37 UTC2020-11N210166-001NCE2023-12-14c0c555d07b60…
2020-11-12 02:37 UTC2020-11N210166-002NCE2023-12-14c0c555d07b60…
2019-12-14 00:12 UTC2019-12N210166-001NCE2023-12-143f01610625f2…
2019-12-14 00:12 UTC2019-12N210166-002NCE2023-12-143f01610625f2…
2019-09-15 20:21 UTC2019-09N210166-001NCE2023-12-14b00525d2431f…
2019-09-15 20:21 UTC2019-09N210166-002NCE2023-12-14b00525d2431f…
2019-07-19 19:46 UTC2019-07N210166-001NCE2023-12-14ea99ee380514…
2019-07-19 19:46 UTC2019-07N210166-002NCE2023-12-14ea99ee380514…
2023-12-20 04:57 UTC2023-12N210166-001NCE2023-12-14ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12N210166-002NCE2023-12-14ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N210166-001NCE2023-12-14a72a2bbeb626…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N210166-002NCE2023-12-14a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N210166-001NCE2023-12-149b2671bbb829…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N210166-002NCE2023-12-149b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N210166-001NCE2023-12-14a67488948f0b…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N210166-002NCE2023-12-14a67488948f0b…

Additional Listing Data#

Finished product
Yes
Brand name base
MOTEGRITY
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PRUCALOPRIDE SUCCINATE1 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4V2G75E1CKInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 4 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2107345Internal RxNorm lookup
2107351Internal RxNorm lookup
2107353Internal RxNorm lookup
2107355Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
bca1e4c6-4b2b-4876-8ab3-654629c4ff1bAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
c75476a7-e531-4d47-9c48-19159bd43a92Product name220251024

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
54092-546-01MOTEGRITY30 in 1 BOTTLETABLET, FILM COATED3012

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
54092-546-01EA - Each54092-546f141b529-b3c6-4a19-94b4-6977c8ddf73612019-03-12

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
54092-546MOTEGRITY (PRUCALOPRIDE) TABLET, FILM COATED [TAKEDA PHARMACEUTICALS AMERICA, INC.]11Current NDC, Legacy NDC, 1 package rows20250311_bca1e4c6-4b2b-4876-8ab3-654629c4ff1b.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
MOTEGRITYPRUCALOPRIDETakeda Pharmaceuticals America, Inc.bca1e4c6-4b2b-4876-8ab3-654629c4ff1b2025-07-17Warnings, Adverse reactionsExact identifier
application applno (NDA): 210166
application number: NDA210166
ndc (product): 54092-546

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2107351motegrity 1 MG Oral TabletPSNbca1e4c6-4b2b-4876-8ab3-654629c4ff1b12
2107355motegrity 2 MG Oral TabletPSNbca1e4c6-4b2b-4876-8ab3-654629c4ff1b12
2107345prucalopride 1 MG Oral TabletPSNbca1e4c6-4b2b-4876-8ab3-654629c4ff1b12
2107353prucalopride 2 MG Oral TabletPSNbca1e4c6-4b2b-4876-8ab3-654629c4ff1b12
2107351prucalopride 1 MG Oral Tablet [Motegrity]SBDbca1e4c6-4b2b-4876-8ab3-654629c4ff1b12
2107355prucalopride 2 MG Oral Tablet [Motegrity]SBDbca1e4c6-4b2b-4876-8ab3-654629c4ff1b12
2107345prucalopride 1 MG Oral TabletSCDbca1e4c6-4b2b-4876-8ab3-654629c4ff1b12
2107353prucalopride 2 MG Oral TabletSCDbca1e4c6-4b2b-4876-8ab3-654629c4ff1b12
2107351Motegrity 1 MG Oral TabletSYbca1e4c6-4b2b-4876-8ab3-654629c4ff1b12
2107355Motegrity 2 MG Oral TabletSYbca1e4c6-4b2b-4876-8ab3-654629c4ff1b12
2107345prucalopride 1 MG (equivalent to prucalopride succinate 1.32 MG) Oral TabletSYbca1e4c6-4b2b-4876-8ab3-654629c4ff1b12
2107353prucalopride 2 MG (equivalent to prucalopride succinate 2.64 MG) Oral TabletSYbca1e4c6-4b2b-4876-8ab3-654629c4ff1b12

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
54092-546-015409205460130 TABLET, FILM COATED in 1 BOTTLE (54092-546-01) 2018-12-140000-00-00NoNoCurrent