Matulane

Product NDC
54482-054
11-digit product format
544820054
Labeler code
54482
Product ID
54482-054_caa705fa-c467-49b5-a7cb-ae2c8b872a86
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
procarbazine hydrochloride
Dosage form
CAPSULE
Route
ORAL
Labeler
Leadiant Biosciences, Inc.
Application
NDA016785
Marketing category
NDA
Marketing start
1985-12-27
Substance
PROCARBAZINE HYDROCHLORIDE
Active strength
50 mg/1
Pharmacologic classes
Alkylating Activity [MoA], Alkylating Drug [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N016785-001MATULANEPROCARBAZINE HYDROCHLORIDEEQ 50MG BASECAPSULE / ORALRLD, RS, Approved before 1982

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-01 22:54:322026-06N016785-001MATULANEEQ 50MG BASECAPSULE / ORALRLD, RS, Approved before 1982a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
MatulanePROCARBAZINE HYDROCHLORIDELeadiant Biosciences, Inc.1aa75a3a-18c9-49e1-91a6-293d0b7da7562024-09-16Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 016785
application number: NDA016785
ndc (product): 54482-054

Additional Listing Data#

Finished product
Yes
Brand name base
Matulane
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PROCARBAZINE HYDROCHLORIDE50 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
XH0NPH5ZX8Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
207588Internal RxNorm lookup
314167Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1aa75a3a-18c9-49e1-91a6-293d0b7da756Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
594e2c86-3079-4e6e-96c9-48f7a8afc78dProduct name120230718
a62a50ac-1535-4461-9768-8ae703e2e9fbProduct name120210525
9514609b-a2a9-f8ec-6ba6-3f8e5ee89877Product name120140508
9959d3f4-2b18-1fd3-aaf3-9a802c197175Product name120140508
bc07ef78-e82d-0c19-31f4-31f263780582Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
54482-054-01Matulane100 in 1 BOTTLECAPSULE1009

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
54482-054-01EA - Each54482-0545984c775-4812-4aa3-8d37-0606f27faeb512018-05-09

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
54482-054MATULANE (PROCARBAZINE HYDROCHLORIDE) CAPSULE [LEADIANT BIOSCIENCES, INC.]9Current NDC, Legacy NDC, 1 package rows20240925_1aa75a3a-18c9-49e1-91a6-293d0b7da756.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
207588Matulane 50 MG Oral CapsulePSN1aa75a3a-18c9-49e1-91a6-293d0b7da7569
314167procarbazine HCl 50 MG Oral CapsulePSN1aa75a3a-18c9-49e1-91a6-293d0b7da7569
207588procarbazine 50 MG Oral Capsule [Matulane]SBD1aa75a3a-18c9-49e1-91a6-293d0b7da7569
314167procarbazine 50 MG Oral CapsuleSCD1aa75a3a-18c9-49e1-91a6-293d0b7da7569
207588Matulane 50 MG Oral CapsuleSY1aa75a3a-18c9-49e1-91a6-293d0b7da7569

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
54482-054-0154482005401100 CAPSULE in 1 BOTTLE (54482-054-01) 100 capsule1985-12-270000-00-00NoNoCurrent