LOTRONEX

Product NDC
54766-895
11-digit product format
547660895
Labeler code
54766
Product ID
54766-895_87fd4e30-01d6-6ab3-e053-2995a90a522f
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
alosetron hydrochloride
Dosage form
TABLET
Route
ORAL
Labeler
Sebela Pharmaceuticals Inc.
Application
NDA021107
Marketing category
NDA
Marketing start
2016-07-11
Marketing end
0000-00-00
Substance
ALOSETRON HYDROCHLORIDE
Active strength
1 mg/1
Pharmacologic classes
Serotonin 3 Receptor Antagonists [MoA],Serotonin-3 Receptor Antagonist [EPC]
NDC exclude flag
No
Listing certified through
2020-12-31
Current FDA listing
Historical FDA.report record

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021107-001LOTRONEXALOSETRON HYDROCHLORIDEEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09
N021107-002LOTRONEXALOSETRON HYDROCHLORIDEEQ 0.5MG BASETABLET / ORALABRLD2003-12-23

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
N021107-001AB
N021107-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09caaa826d4ba7…
2026-08-18 06:07:402026-07N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-2331067a03dcf5…
2025-08-23 18:47 UTC2025-08N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-236a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-2303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-232680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-095bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-235bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09d06236e962d9…
2024-10-29 15:01 UTC2024-10N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-0979d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-2379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-091e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-231e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-098072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-238072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-095c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-235c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-095d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-235d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-094b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-234b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-0974a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-2374a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021107-001LOTRONEXEQ 1MG BASETABLET / ORALABRLD, RS2000-02-09bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021107-002LOTRONEXEQ 0.5MG BASETABLET / ORALABRLD2003-12-23bb7c543d1eb4…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N021107-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07N021107-002AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N021107-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021107-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021107-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021107-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N021107-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021107-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021107-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021107-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021107-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021107-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021107-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021107-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021107-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021107-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021107-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021107-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021107-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021107-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021107-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N021107-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021107-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021107-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021107-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021107-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021107-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021107-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021107-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021107-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021107-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021107-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021107-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021107-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021107-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021107-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021107-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021107-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021107-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021107-002AB1bb7c543d1eb4…

Additional Listing Data#

Finished product
Yes
Brand name base
LOTRONEX
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ALOSETRON HYDROCHLORIDE1 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2F5R1A46YWInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 4 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
259306Internal RxNorm lookup
261362Internal RxNorm lookup
403975Internal RxNorm lookup
540181Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
35cbb9d5-639b-207a-e054-00144ff88e88Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
351abe41-466c-4dd8-840a-0fdb68318bd5Product name120230316
9a726e57-9bfe-419e-b2fb-835ed905be3dProduct name620210511

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
54766-895LOTRONEX (ALOSETRON HYDROCHLORIDE) TABLET [SEBELA PHARMACEUTICALS INC.]4Legacy NDC20190507_35cbb9d5-639b-207a-e054-00144ff88e88.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
LOTRONEXALOSETRON HYDROCHLORIDESebela Pharmaceuticals Inc.35cbb9d5-639b-207a-e054-00144ff88e882026-06-30Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 021107
application number: NDA021107
ndc (product): 54766-895
LOTRONEXALOSETRON HYDROCHLORIDELegacy Pharma USA Inc.c216e967-436f-475a-8e6a-2ad11adc63af2026-03-23Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 021107
application number: NDA021107

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
54766-895-035476608950330 TABLET in 1 BOTTLE (54766-895-03) 30 tablet2016-07-110000-00-00NoNoCurrent