Bumetanide

Product NDC
55154-1527
11-digit product format
551541527
Labeler code
55154
Product ID
55154-1527_5b9e8d84-41f6-4f90-a714-3b0703cfbba5
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Bumetanide
Dosage form
INJECTION
Route
INTRAMUSCULAR; INTRAVENOUS
Labeler
Cardinal Health 107, LLC
Application
ANDA215364
Marketing category
ANDA
Marketing start
2024-10-21
Substance
BUMETANIDE
Active strength
.25 mg/mL
Pharmacologic classes
Increased Diuresis at Loop of Henle [PE], Loop Diuretic [EPC]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A215364-001BUMETANIDEBUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A215364-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-0431067a03dcf5…
2025-08-23 18:47 UTC2025-08A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-046a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-0403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-042680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-045bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-0479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-041e350fbaab3a…
2024-05-31 18:47 UTC2024-05A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-048072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-046a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-041c564ffb4f44…
2023-12-20 04:57 UTC2023-12A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-049b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-043f0d92c62455…
2023-05-13 08:27 UTC2023-05A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04053a50430f4f…
2023-01-26 05:58 UTC2023-01A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-043bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-043a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04e64feba35796…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A215364-001BUMETANIDE0.25MG/MLINJECTABLE / INJECTIONAP2022-08-04a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A215364-001AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A215364-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215364-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A215364-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215364-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215364-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215364-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215364-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215364-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215364-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A215364-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A215364-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A215364-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A215364-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A215364-001AP18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A215364-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A215364-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A215364-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A215364-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A215364-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A215364-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A215364-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A215364-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A215364-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A215364-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A215364-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A215364-001AP1e64feba35796…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A215364-001AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Bumetanide
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BUMETANIDE.25 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
0Y2S3XUQ5HInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1727569Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
68f18d36-ffc2-4481-9286-914cfcf573a0Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
1d3f2f0a-cce7-32fe-77bf-6ee61839e736Product name920260113
601d9750-f415-d9d9-619c-0a87b4d3f237Product name320250331
1d3f2f0a-cce7-32fe-77bf-6ee61839e736Product name220171211

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
55154-1527-5Bumetanide4 mL in 1 VIALINJECTION43
55154-1527-5Bumetanide5 in 1 BAGINJECTION53

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
55154-1527BUMETANIDE INJECTION [CARDINAL HEALTH 107, LLC]1Current NDC, 2 package rows20241023_68f18d36-ffc2-4481-9286-914cfcf573a0.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
BumetanideBUMETANIDEBryant Ranch Prepack43ab2dd6-39ba-4a53-aa84-d7975038ef432026-05-06Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215364
application number: ANDA215364
BumetanideBUMETANIDEBryant Ranch Prepack37179b2d-6589-40d8-8121-7561a6791d382026-05-06Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215364
application number: ANDA215364
BumetanideBUMETANIDECardinal Health 107, LLC68f18d36-ffc2-4481-9286-914cfcf573a02026-04-14Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215364
application number: ANDA215364
ndc (product): 55154-1527
BumetanideBUMETANIDENovadoz Pharmaceuticals LLC387edfd4-be85-41cd-8a6d-14e6a022b5a92022-08-09Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215364
application number: ANDA215364

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1727569bumetanide 1 MG in 4 ML InjectionPSN68f18d36-ffc2-4481-9286-914cfcf573a03
17275694 ML bumetanide 0.25 MG/ML InjectionSCD68f18d36-ffc2-4481-9286-914cfcf573a03
1727569bumetanide 1 MG per 4 ML InjectionSY68f18d36-ffc2-4481-9286-914cfcf573a03

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
55154-1527-5551541527055 VIAL in 1 BAG (55154-1527-5) / 4 mL in 1 VIAL5 vial2024-10-21NoNoCurrent