Diphenhydramine HCl Oral Solution

Product NDC
57237-318
11-digit product format
572370318
Labeler code
57237
Product ID
57237-318_deb36161-32a5-4e95-9837-fd12ca2c3778
Type
HUMAN OTC DRUG
Nonproprietary name
Diphenhydramine HCl Oral
Dosage form
SOLUTION
Route
ORAL
Labeler
Rising Pharma Holdings, Inc.
Application
M009.50
Marketing category
OTC MONOGRAPH DRUG
Marketing start
2023-12-15
Substance
DIPHENHYDRAMINE HYDROCHLORIDE
Active strength
25 mg/10mL
Pharmacologic classes
Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Additional Listing Data#

Finished product
Yes
Brand name base
Diphenhydramine HCl Oral Solution
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DIPHENHYDRAMINE HYDROCHLORIDE25 mg/10mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
TC2D6JAD40Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1049906Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
8f0ba9e5-a31d-4d77-8155-c16c7e74edefAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
0e2e0f88-b076-afe1-4bdd-32bca4375becProduct name320250127
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831
3e48c9c4-918d-5d23-2f0b-d2398b06be54Product name120140508
865c72dd-0d94-daac-f728-ddd4ded2a79eProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
57237-318-01Diphenhydramine HCl Oral Solution10 mL in 1 CUP, UNIT-DOSESOLUTION103
57237-318-11Diphenhydramine HCl Oral Solution100 in 1 BOX, UNIT-DOSESOLUTION1003

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
57237-318-01ML - Milliliter57237-31868c91723-6496-40f9-acb3-9533ba0ffe8412024-04-05
57237-318-11ML - Milliliter57237-3181e834ec8-4814-45ec-884d-f12e845892f712024-03-12

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
57237-318DIPHENHYDRAMINE HCL ORAL SOLUTION (DIPHENHYDRAMINE HCL ORAL) SOLUTION [RISING PHARMA HOLDINGS, INC.]2Current NDC, 2 package rows20241019_8f0ba9e5-a31d-4d77-8155-c16c7e74edef.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Diphenhydramine HCl Oral SolutionDIPHENHYDRAMINE HCL ORALRising Pharma Holdings, Inc.8f0ba9e5-a31d-4d77-8155-c16c7e74edef2025-07-01WarningsExact identifier
ndc (product): 57237-318

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1049906diphenhydrAMINE HCl 12.5 MG in 5 mL Oral SolutionPSN8f0ba9e5-a31d-4d77-8155-c16c7e74edef3
1049906diphenhydramine hydrochloride 2.5 MG/ML Oral SolutionSCD8f0ba9e5-a31d-4d77-8155-c16c7e74edef3
1049906diphenhydramine HCl 12.5 MG per 5 ML Oral SolutionSY8f0ba9e5-a31d-4d77-8155-c16c7e74edef3
1049906diphenhydramine hydrochloride 25 MG per 10 ML Oral SolutionSY8f0ba9e5-a31d-4d77-8155-c16c7e74edef3
1049906diphenhydramine hydrochloride 50 MG per 20 ML Oral SolutionSY8f0ba9e5-a31d-4d77-8155-c16c7e74edef3

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
57237-318-015723703180110 mL in 1 CUP, UNIT-DOSE10 mlHistorical
57237-318-1157237031811100 CUP, UNIT-DOSE in 1 BOX, UNIT-DOSE (57237-318-11) / 10 mL in 1 CUP, UNIT-DOSE (57237-318-01) 2023-12-15NoNoCurrent