ENVIRONMENTAL DEFENSE

Product NDC: 58518-010
11-digit product format: 585180010
Labeler code: 58518
Product ID: 58518-010_49534937-860f-bf99-e063-6394a90a0e02
Type: HUMAN OTC DRUG
Nonproprietary name: ZINC OXIDE
Dosage form: CREAM
Route: TOPICAL
Labeler: Avasol LLC
Application: M020
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2013-07-18
Substance: ZINC OXIDE
Active strength: 225 mg/100mL
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 2 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Archive	Snapshot	Source SHA-256
2019-12-08 06:16 UTC · source 2019-12-05	excluded product	product	58518-010		I	Inactivated by FDA		excluded / ndc_excluded.zip	`110d247fa046…`	`a55b01930146…`
2019-12-08 06:16 UTC · source 2019-12-05	excluded package	package	58518-010	58518-010-01	I	Inactivated by FDA		excluded / ndc_excluded.zip	`110d247fa046…`	`a55b01930146…`

Additional Listing Data#

Finished product: Yes
Brand name base: ENVIRONMENTAL DEFENSE
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
ZINC OXIDE	225 mg/100mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
SOI2LOH54Z	Internal UNII lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1fbddab4-71f7-4167-ad21-30040b7c71bb	Available on FDA.report

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Related label table
NDC	Effective	Related label
58518-010-01	2023-04-20	ENVIRONMENTAL DEFENSE- zinc oxide
58518-010-02	2023-04-20	ENVIRONMENTAL DEFENSE- zinc oxide
58518-010-01	2023-01-30	ENVIRONMENTAL DEFENSE- zinc oxide
58518-010-02	2023-01-30	ENVIRONMENTAL DEFENSE- zinc oxide
58518-010-01	2020-01-02	ENVIRONMENTAL DEFENSE- zinc oxide
58518-010-01	2019-11-27	ENVIRONMENTAL DEFENSE- zinc oxide

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
58518-010-02	ENVIRONMENTAL DEFENSE	60 mL in 1 POUCH	CREAM	60		6

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
ZINC OXIDE	ACTIVE INGREDIENT	SOI2LOH54Z	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
ZINC OXIDE	ACTIVE MOIETY	SOI2LOH54Z	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
ARGAN OIL	INACTIVE INGREDIENT	4V59G5UW9X	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
CANDELILLA WAX	INACTIVE INGREDIENT	WL0328HX19	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
CHINESE CINNAMON LEAF OIL	INACTIVE INGREDIENT	4U4V2F2E4Y	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
EMU OIL	INACTIVE INGREDIENT	344821WD61	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
FERROUS OXIDE	INACTIVE INGREDIENT	G7036X8B5H	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
HAEMATOCOCCUS PLUVIALIS	INACTIVE INGREDIENT	31T0FF0472	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
JOJOBA OIL	INACTIVE INGREDIENT	724GKU717M	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
MANUKA OIL	INACTIVE INGREDIENT	M6QU9ZUH2X	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
MAURITIA FLEXUOSA WHOLE	INACTIVE INGREDIENT	83ULF8L5FI	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
MEDIUM-CHAIN TRIGLYCERIDES	INACTIVE INGREDIENT	C9H2L21V7U	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
MICA	INACTIVE INGREDIENT	V8A1AW0880	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
PROPOLIS WAX	INACTIVE INGREDIENT	6Y8XYV2NOF	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
ROSEMARY	INACTIVE INGREDIENT	IJ67X351P9	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
RUBUS IDAEUS SEED	INACTIVE INGREDIENT	M3CL7US2ZG	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
SHEANUT	INACTIVE INGREDIENT	84H6HBP32L	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
SILICON DIOXIDE	INACTIVE INGREDIENT	ETJ7Z6XBU4	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
SUNFLOWER OIL	INACTIVE INGREDIENT	3W1JG795YI	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
TAMANU OIL	INACTIVE INGREDIENT	JT3LVK84A1	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
THEOBROMA GRANDIFLORUM SEED	INACTIVE INGREDIENT	Q7RNT1G37V	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
TOCOPHEROL	INACTIVE INGREDIENT	R0ZB2556P8	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1
YELLOW WAX	INACTIVE INGREDIENT	2ZA36H0S2V	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
58518-010	ENVIRONMENTAL DEFENSE (ZINC OXIDE) CREAM [AVASOL LLC]	5	Current NDC, Legacy NDC, 1 package rows	20241222_1fbddab4-71f7-4167-ad21-30040b7c71bb.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 361 · 7,202 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
ISNTREE HYALURONIC ACID SENSITIVE SUNSCREEN	ZINC OXIDE	ISNTREE Inc.	58e38665-0bca-fb02-e063-6394a90ad62a	2026-08-13	Warnings	Exact identifier application number: M020
Neutrogena Ultra Sheer Daily Face Sunscreen Broad Spectrum SPF 70	AVOBENZONE, BEMOTRIZINOL, HOMOSALATE, OCTISALATE	Kenvue Brands LLC	58d3d390-8b88-a6fe-e063-6394a90a9bf8	2026-08-12	Warnings	Exact identifier application number: M020
Neutrogena Clear Face Sunscreen Acne Prone Skin Broad Spectrum SPF 60	AVOBENZONE, BEMOTRIZINOL, HOMOSALATE, OCTISALATE	Kenvue Brands LLC	58d7a3e3-b7df-43ce-e063-6294a90a729c	2026-08-12	Warnings	Exact identifier application number: M020
Elta MD Skincare UV Stick Broad Spectrum SPF50	ZINC OXIDE	CP Skin Health Group, Inc	58dd81db-46d4-d763-e063-6394a90abb0b	2026-08-12	Warnings	Exact identifier application number: M020
UV Skin Recovery SPF 50 Red Correcting	ZINC OXIDE	CP Skin Health Group, Inc.	26e63890-d1af-d171-e063-6394a90af828	2026-08-12	Warnings	Exact identifier application number: M020
UV Skin Recovery SPF 50	ZINC OXIDE	CP Skin Health Group, Inc.	26d2683f-cfd5-50fd-e063-6394a90a7576	2026-08-12	Warnings	Exact identifier application number: M020
doTERRA Sun Body	MINERAL SUNSCREEN	doTERRA International, LLC	58dcc56f-f093-469c-e063-6394a90a6088	2026-08-12	Warnings	Exact identifier application number: M020
Colorescience Total Protection Body Shield Glow	ZINC OXIDE	Colorescience	52e1d987-a4f8-195e-e063-6294a90a5629	2026-08-11	Warnings	Exact identifier application number: M020
Stay Ageless Tinted Mineral Sunscreen	BROAD SPECTRUM SPF30	DR. SAMRAO'S OFFICE	58b2ca35-11ed-d848-e063-6294a90a5b37	2026-08-11	Warnings	Exact identifier application number: M020
Ciele Tint and Protect	ZINC OXIDE	Ciele	0162d9c9-07fa-9210-e063-6294a90aa687	2026-08-11	Warnings	Exact identifier application number: M020
NeoStrata Skin Active Matrix Support SPF 30	AVOBENZONE, OCTINOXATE, AND OCTISALATE	NeoStrata Company Inc.	8e4b9c08-b906-4c5f-a243-55838ae28b90	2026-08-10	Warnings	Exact identifier application number: M020
HEADHUNTER SURF SCREEN SPF 50 SUNSCREEN	ZINC OXIDE,TITANIUM DIOXIDE	Guangzhou Tata Biotechnology Co., Ltd.	4339df13-77d3-31a1-e063-6394a90a5208	2026-08-10	Warnings	Exact identifier application number: M020
Sunscreen for Kids SPF 50	AVOBENZONE, HOMOSALATE, OCTISALATE	The Kroger Co.	1c7cd904-ffff-48aa-91bd-cc978946b36a	2026-08-10	Warnings, Adverse reactions	Exact identifier application number: M020
Sport Sunscreen SPF 50	AVOBENZONE, HOMOSALATE, OCTISALATE	The Kroger Co.	22aa46af-5d0f-4256-8f45-be06f6627561	2026-08-10	Warnings	Exact identifier application number: M020
Colorescience Total Protection No Show Mineral Body Shield	ZINC OXIDE	Colorescience	52e1f59e-63cb-7480-e063-6394a90ad7c5	2026-08-10	Warnings	Exact identifier application number: M020
Journee Firm Riche Broad Spectrum Sunscreen SPF 30	TITANIUM DIOXIDE AND ZINC OXIDE	Merz North America, Inc.	d4d4bfcf-3674-4847-8ad8-1716a8e821ae	2026-08-10	Warnings	Exact identifier application number: M020
ULTRA VIOLETTE Unblock Screen SPF 50 Sunscreen	BEMOTRIZINOL, OCTOCRYLENE, ZINC OXIDE	Grace and Fire USA Inc.	56ad0dce-410e-9d78-e063-6294a90a1c3e	2026-08-09	Warnings	Exact identifier application number: M020
ORLASKIN SPF50 Antioxidant SoothingComplex Sunscreen	ETHYLHEXYL METHOXYCINNAMATE ETHYLHEXYL SALICYLATE BUTYL METHOXYDIBENZOYLMETHANE ZINC OXIDE BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE	Guangzhou Yapheon Health Industry Co., Ltd.	552a36ed-7a66-4048-e063-6394a90a09bc	2026-08-08	Warnings	Exact identifier application number: M020
lip balm SPF15( 2533) 01	AVOBENZONE,HOMOSALATE,OCTOCRYLENE,OCTISALATE	Cosmuses Cosmetics (Ningbo) Co., Ltd.	5870aa44-1375-cdc5-e063-6394a90af4a5	2026-08-07	Warnings	Exact identifier application number: M020
lip balm SPF15( Zinc oxide) 01	ZINC OXIDE	Cosmuses Cosmetics (Ningbo) Co., Ltd.	5871ab1d-cf07-d737-e063-6394a90a58fe	2026-08-07	Warnings	Exact identifier application number: M020

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
SOI2LOH54Z	ZINC OXIDE	1314-13-2	ZINC OXIDE

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
58518-010-01	58518001001	75 mL in 1 BOTTLE, PUMP (58518-010-01)	75 ml	2013-07-18	0000-00-00	No	No	Current
58518-010-02	58518001002	60 mL in 1 POUCH (58518-010-02)	60 ml	2021-11-29	0000-00-00	No	No	Current