captopril

Product NDC
58657-738
11-digit product format
586570738
Labeler code
58657
Product ID
58657-738_457502be-feb2-5e2f-e063-6394a90aec0b
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
captopril
Dosage form
TABLET
Route
ORAL
Labeler
Method Pharmaceuticals LLC
Application
ANDA074677
Marketing category
ANDA
Marketing start
2024-06-15
Substance
CAPTOPRIL
Active strength
100 mg/1
Pharmacologic classes
Angiotensin Converting Enzyme Inhibitor [EPC], Angiotensin-converting Enzyme Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 4 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A074677-001CAPTOPRILCAPTOPRIL50MGTABLET / ORALAB1997-05-30
A074677-002CAPTOPRILCAPTOPRIL25MGTABLET / ORALAB1997-05-30
A074677-003CAPTOPRILCAPTOPRIL100MGTABLET / ORALAB1997-05-30
A074677-004CAPTOPRILCAPTOPRIL12.5MGTABLET / ORALAB1997-05-30

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 4 matching rows.

Application-product, TE code table
Application-productTE code
A074677-001AB
A074677-002AB
A074677-003AB
A074677-004AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 5 · 164 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A074677-001CAPTOPRIL50MGTABLET / ORALAB1997-05-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02A074677-002CAPTOPRIL25MGTABLET / ORALAB1997-05-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02A074677-003CAPTOPRIL100MGTABLET / ORALAB1997-05-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02A074677-004CAPTOPRIL12.5MGTABLET / ORALAB1997-05-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074677-001CAPTOPRIL50MGTABLET / ORALAB1997-05-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074677-002CAPTOPRIL25MGTABLET / ORALAB1997-05-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074677-003CAPTOPRIL100MGTABLET / ORALAB1997-05-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074677-004CAPTOPRIL12.5MGTABLET / ORALAB1997-05-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08A074677-001CAPTOPRIL50MGTABLET / ORALAB1997-05-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08A074677-002CAPTOPRIL25MGTABLET / ORALAB1997-05-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08A074677-003CAPTOPRIL100MGTABLET / ORALAB1997-05-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08A074677-004CAPTOPRIL12.5MGTABLET / ORALAB1997-05-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074677-001CAPTOPRIL50MGTABLET / ORALAB1997-05-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074677-002CAPTOPRIL25MGTABLET / ORALAB1997-05-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074677-003CAPTOPRIL100MGTABLET / ORALAB1997-05-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074677-004CAPTOPRIL12.5MGTABLET / ORALAB1997-05-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074677-001CAPTOPRIL50MGTABLET / ORALAB1997-05-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074677-002CAPTOPRIL25MGTABLET / ORALAB1997-05-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074677-003CAPTOPRIL100MGTABLET / ORALAB1997-05-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074677-004CAPTOPRIL12.5MGTABLET / ORALAB1997-05-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074677-001CAPTOPRIL50MGTABLET / ORALAB1997-05-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074677-002CAPTOPRIL25MGTABLET / ORALAB1997-05-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074677-003CAPTOPRIL100MGTABLET / ORALAB1997-05-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074677-004CAPTOPRIL12.5MGTABLET / ORALAB1997-05-3003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074677-001CAPTOPRIL50MGTABLET / ORALAB1997-05-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074677-002CAPTOPRIL25MGTABLET / ORALAB1997-05-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074677-003CAPTOPRIL100MGTABLET / ORALAB1997-05-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074677-004CAPTOPRIL12.5MGTABLET / ORALAB1997-05-302680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074677-001CAPTOPRIL50MGTABLET / ORALAB1997-05-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074677-002CAPTOPRIL25MGTABLET / ORALAB1997-05-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074677-003CAPTOPRIL100MGTABLET / ORALAB1997-05-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074677-004CAPTOPRIL12.5MGTABLET / ORALAB1997-05-305bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074677-001CAPTOPRIL50MGTABLET / ORALAB1997-05-30d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074677-002CAPTOPRIL25MGTABLET / ORALAB1997-05-30d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074677-003CAPTOPRIL100MGTABLET / ORALAB1997-05-30d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074677-004CAPTOPRIL12.5MGTABLET / ORALAB1997-05-30d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A074677-001CAPTOPRIL50MGTABLET / ORALAB1997-05-30d06236e962d9…
2024-10-29 15:01 UTC2024-10A074677-002CAPTOPRIL25MGTABLET / ORALAB1997-05-30d06236e962d9…
2024-10-29 15:01 UTC2024-10A074677-003CAPTOPRIL100MGTABLET / ORALAB1997-05-30d06236e962d9…
2024-10-29 15:01 UTC2024-10A074677-004CAPTOPRIL12.5MGTABLET / ORALAB1997-05-30d06236e962d9…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 5 · 164 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A074677-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A074677-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A074677-003AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A074677-004AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074677-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074677-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074677-003AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074677-004AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A074677-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A074677-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A074677-003AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A074677-004AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074677-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074677-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074677-003AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074677-004AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074677-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074677-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074677-003AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074677-004AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074677-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074677-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074677-003AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074677-004AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074677-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074677-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074677-003AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074677-004AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074677-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074677-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074677-003AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074677-004AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074677-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074677-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074677-003AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074677-004AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A074677-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A074677-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A074677-003AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A074677-004AB1d06236e962d9…

Additional Listing Data#

Finished product
Yes
Brand name base
captopril
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CAPTOPRIL100 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9G64RSX1XDInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 4 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
308962Internal RxNorm lookup
308963Internal RxNorm lookup
308964Internal RxNorm lookup
317173Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1a91ac7f-b75d-d111-e063-6394a90a2a93Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
d5efca61-58ec-b4d0-77f8-f2b1fb112156Product name420240223

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
58657-738-01captopril100 in 1 BOTTLETABLET1003
58657-738-50captopril500 in 1 BOTTLETABLET5003

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
58657-738-01EA - Each58657-73843417336-f008-4344-bde3-1b43afc41d9d12024-09-09

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
58657-738CAPTOPRIL TABLET [METHOD PHARMACEUTICALS LLC]1Current NDC, 2 package rows20240617_1a91ac7f-b75d-d111-e063-6394a90a2a93.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
captoprilCAPTOPRILMethod Pharmaceuticals LLC1a91ac7f-b75d-d111-e063-6394a90a2a932025-12-08Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074677
application number: ANDA074677
ndc (product): 58657-738
captoprilCAPTOPRILBryant Ranch Prepackccbffd30-4b21-4522-bdb8-abba8d5920172025-06-26Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074677
application number: ANDA074677
captoprilCAPTOPRILAMICI PHARMACEUTICALS LLC1395ba5b-2fc9-41ff-9c43-e0740d781dee2022-09-13Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074677
application number: ANDA074677

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
308962captopril 100 MG Oral TabletPSN1a91ac7f-b75d-d111-e063-6394a90a2a933
308963captopril 12.5 MG Oral TabletPSN1a91ac7f-b75d-d111-e063-6394a90a2a933
317173captopril 25 MG Oral TabletPSN1a91ac7f-b75d-d111-e063-6394a90a2a933
308964captopril 50 MG Oral TabletPSN1a91ac7f-b75d-d111-e063-6394a90a2a933
308962captopril 100 MG Oral TabletSCD1a91ac7f-b75d-d111-e063-6394a90a2a933
308963captopril 12.5 MG Oral TabletSCD1a91ac7f-b75d-d111-e063-6394a90a2a933
317173captopril 25 MG Oral TabletSCD1a91ac7f-b75d-d111-e063-6394a90a2a933
308964captopril 50 MG Oral TabletSCD1a91ac7f-b75d-d111-e063-6394a90a2a933

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
58657-738-0158657073801100 TABLET in 1 BOTTLE (58657-738-01) 100 tablet2024-06-15NoNoCurrent
58657-738-5058657073850500 TABLET in 1 BOTTLE (58657-738-50) 500 tablet2024-06-15NoNoCurrent