Pyridostigmine Bromide

Product NDC
58657-811
11-digit product format
586570811
Labeler code
58657
Product ID
58657-811_4aa4cfc7-d427-5306-e063-6394a90a628d
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
PYRIDOSTIGMINE BROMIDE
Dosage form
TABLET
Route
ORAL
Labeler
Method Pharmaceuticals, LLC
Application
ANDA211181
Marketing category
ANDA
Marketing start
2024-06-15
Substance
PYRIDOSTIGMINE BROMIDE
Active strength
60 mg/1
Pharmacologic classes
Cholinesterase Inhibitor [EPC], Cholinesterase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A211181-001PYRIDOSTIGMINE BROMIDEPYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-20
A211181-002PYRIDOSTIGMINE BROMIDEPYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-14

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A211181-001AB
A211181-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-14011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-1431067a03dcf5…
2025-08-23 18:47 UTC2025-08A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-146a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-14fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-14b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-1403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-142680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-205bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-145bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-20d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-14d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-20d06236e962d9…
2024-10-29 15:01 UTC2024-10A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-14d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-2079d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-1479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-20301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-14301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-201e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-141e350fbaab3a…
2024-05-31 18:47 UTC2024-05A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-208072bd15b7f6…
2024-05-31 18:47 UTC2024-05A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORALAB2019-05-148072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-205c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORAL2019-05-145c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-205d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORAL2019-05-145d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-204b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORAL2019-05-144b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-2074a2ff9319b5…
2019-12-13 00:20 UTC2019-12A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORAL2019-05-1474a2ff9319b5…
2022-03-09 01:35 UTC2022-03A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-20bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORAL2019-05-14bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A211181-001PYRIDOSTIGMINE BROMIDE60MGTABLET / ORALAB2018-07-20782e0a99824c…
2021-12-28 21:50 UTC2021-12A211181-002PYRIDOSTIGMINE BROMIDE30MGTABLET / ORAL2019-05-14782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 69 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A211181-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211181-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211181-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211181-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A211181-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211181-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211181-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211181-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211181-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211181-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211181-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211181-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211181-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211181-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211181-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211181-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211181-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211181-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211181-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A211181-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211181-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211181-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211181-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211181-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211181-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211181-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A211181-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A211181-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211181-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A211181-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A211181-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A211181-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A211181-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A211181-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A211181-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A211181-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A211181-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A211181-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A211181-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A211181-001AB1b00525d2431f…

Additional Listing Data#

Finished product
Yes
Brand name base
Pyridostigmine Bromide
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PYRIDOSTIGMINE BROMIDE60 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
KVI301NA53Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
903857Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1aa7a886-c726-cc91-e063-6294a90a1af1Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
cd6f4a37-8abf-2ed8-817f-5becdfa53ca5Product name920230112
dd640b44-88ec-4cbe-02c0-23127b95f5d3Product name120140508

FDA-Initiated Inactive NDC Indexing#

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
58657-811-01Pyridostigmine Bromide100 in 1 BOTTLETABLET1002
58657-811-30Pyridostigmine Bromide30 in 1 BOTTLETABLET302
58657-811-90Pyridostigmine Bromide90 in 1 BOTTLETABLET902

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
58657-811PYRIDOSTIGMINE BROMIDE TABLET [METHOD PHARMACEUTICALS, LLC]1Current NDC, 3 package rows20240619_1aa7a886-c726-cc91-e063-6294a90a1af1.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Pyridostigmine BromidePYRIDOSTIGMINE BROMIDEMethod Pharmaceuticals, LLC1aa7a886-c726-cc91-e063-6294a90a1af12026-02-12Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211181
application number: ANDA211181
ndc (product): 58657-811
Pyridostigmine BromidePYRIDOSTIGMINE BROMIDEMethod Pharmaceuticals, LLCe756717f-941b-42f2-ba3b-03798c005ae72025-10-21Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211181
application number: ANDA211181

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
903857pyRIDostigmine bromide 60 MG Oral TabletPSN1aa7a886-c726-cc91-e063-6294a90a1af12
903857pyridostigmine bromide 60 MG Oral TabletSCD1aa7a886-c726-cc91-e063-6294a90a1af12

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
58657-811-0158657081101100 TABLET in 1 BOTTLE (58657-811-01) 100 tablet2024-06-15NoNoCurrent
58657-811-305865708113030 TABLET in 1 BOTTLE (58657-811-30) 30 tablet2024-06-15NoNoCurrent
58657-811-905865708119090 TABLET in 1 BOTTLE (58657-811-90) 90 tablet2024-06-15NoNoCurrent