Tretinoin

Product NDC
59651-713
11-digit product format
596510713
Labeler code
59651
Product ID
59651-713_50b05c90-bdd9-4766-b285-52bd88c4c740
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Tretinoin
Dosage form
GEL
Route
TOPICAL
Labeler
Aurobindo Pharma Limited
Application
ANDA218245
Marketing category
ANDA
Marketing start
2025-02-27
Substance
TRETINOIN
Active strength
.25 mg/g
Pharmacologic classes
Retinoid [EPC], Retinoids [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A218245-001TRETINOINTRETINOIN0.025%GEL / TOPICALAB2025-02-27

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A218245-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A218245-001TRETINOIN0.025%GEL / TOPICALAB2025-02-27011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218245-001TRETINOIN0.025%GEL / TOPICALAB2025-02-2731067a03dcf5…
2025-08-23 18:47 UTC2025-08A218245-001TRETINOIN0.025%GEL / TOPICALAB2025-02-276a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218245-001TRETINOIN0.025%GEL / TOPICALAB2025-02-27fd3edfee7708…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218245-001TRETINOIN0.025%GEL / TOPICALAB2025-02-27a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A218245-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218245-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A218245-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218245-001AB1fd3edfee7708…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218245-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Tretinoin
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TRETINOIN.25 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
5688UTC01RInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
313451Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
dea325b5-3cb8-4ffb-84e9-782f0e3f6b0eAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
b80ad7bc-1b6f-7ef4-1ed0-86cd9f459d60Product name620251124
1426d8f8-b7d5-4053-8554-613df00c0d86Product name220250616
0e7b8bf1-c46c-4de6-b26a-0c50e34364ecProduct name220250521
e3af9708-3004-7392-4046-5311eaa8bab5Product name320221128
13e7e7e3-e885-4c79-af6d-dad1aedbb06eProduct name120220128
503b047e-e62d-4745-9011-522b13bc701bProduct name120181206
7d41caa2-0b5d-9b03-ab8d-84271de26ef4Product name220170314
50ca9ff5-82dd-9971-4f2c-5845a76a8572Product name220150818
0a8118e4-08c6-b395-9ddc-d3e425e0493aProduct name120140508
233bcb0a-cf40-b0a1-b346-c83ac2f43579Product name120140508
85490a6b-2306-6bf2-c51b-eb63537dc2daProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
59651-713-14Tretinoin15 g in 1 TUBEGEL153
59651-713-14Tretinoin1 in 1 CARTONGEL13
59651-713-46Tretinoin45 g in 1 TUBEGEL453
59651-713-46Tretinoin1 in 1 CARTONGEL13

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
59651-713-14GM - Gram59651-7133e75def2-9efd-465b-a701-d01c2526611612026-02-05
59651-713-46GM - Gram59651-7137fb8bf09-b14c-4ba5-b8d5-f1cba1b62f8512026-02-05

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
59651-713TRETINOIN GEL [AUROBINDO PHARMA LIMITED]2Current NDC, 4 package rows20250408_dea325b5-3cb8-4ffb-84e9-782f0e3f6b0e.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TretinoinTRETINOINAurobindo Pharma Limiteddea325b5-3cb8-4ffb-84e9-782f0e3f6b0e2025-06-19Warnings, Adverse reactionsExact identifier
application applno (ANDA): 218245
application number: ANDA218245
ndc (product): 59651-713

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
313451tretinoin 0.025 % Topical GelPSNdea325b5-3cb8-4ffb-84e9-782f0e3f6b0e3
313451tretinoin 0.00025 MG/MG Topical GelSCDdea325b5-3cb8-4ffb-84e9-782f0e3f6b0e3
313451tretinoin 0.025 % Topical GelSYdea325b5-3cb8-4ffb-84e9-782f0e3f6b0e3

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
59651-713-14596510713141 TUBE in 1 CARTON (59651-713-14) / 15 g in 1 TUBE1 tube2025-02-27NoNoCurrent
59651-713-46596510713461 TUBE in 1 CARTON (59651-713-46) / 45 g in 1 TUBE1 tube2025-02-27NoNoCurrent