Memantine Hydrochloride

Product NDC
60505-6210
Requested package NDC
60505-6210-3
11-digit product format
605056210
Labeler code
60505
Product ID
60505-6210_6cfcef62-aadf-4c12-9fa7-2e8cb65f8d54
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
memantine hydrochloride
Dosage form
CAPSULE, EXTENDED RELEASE
Route
ORAL
Labeler
Apotex Corp
Application
NDA022525
Marketing category
NDA
Marketing start
2019-05-09
Marketing end
0000-00-00
Substance
MEMANTINE HYDROCHLORIDE
Active strength
21 mg/1
Pharmacologic classes
N-methyl-D-aspartate Receptor Antagonist [EPC], NMDA Receptor Antagonists [MoA]
NDC exclude flag
No
Listing certified through
2023-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

Explicit status records from FDA unfinished, excluded, and compounder auxiliary files. Absence of a row is not itself a regulatory status. Browse every current auxiliary row, including rows without a usable NDC. · Browse every captured source and parsed snapshot.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded packagepackage60505-621060505-6210-3DDiscontinued by firm2026-08-03

Observed NDC auxiliary status history#

Observed captured status history: Rows come only from successfully parsed FDA auxiliary ZIP captures. They show the state present in that artifact, not a continuous regulatory timeline. Absence before, after, or between captures is not proof of status, and a known non-data HTTP 403 capture is preserved in backfill provenance but cannot produce a status row.

Historic NDC status page 1 of 1 · 2 matching rows.

Browse every current auxiliary row. · Browse the complete NDC auxiliary source catalog.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopeProduct NDCPackage NDCCodeStatusReporting periodArchiveSnapshotSource SHA-256
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage60505-621060505-6210-3DDiscontinued by firmexcluded / ndc_excluded.zip367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage60505-621060505-6210-3DDiscontinued by firmexcluded / ndc_excluded.zip557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 4 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N022525-001NAMENDA XRMEMANTINE HYDROCHLORIDE7MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21
N022525-002NAMENDA XRMEMANTINE HYDROCHLORIDE14MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21
N022525-003NAMENDA XRMEMANTINE HYDROCHLORIDE21MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21
N022525-004NAMENDA XRMEMANTINE HYDROCHLORIDE28MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21

Orange Book patents#

Current patent rows page 1 of 1 · 8 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N022525-00180390092029-03-24U-5392011-11-16
N022525-0018039009*PED2029-09-24Pediatric extension
N022525-00280390092029-03-24U-539
N022525-0028039009*PED2029-09-24Pediatric extension
N022525-00380390092029-03-24U-539
N022525-0038039009*PED2029-09-24Pediatric extension
N022525-00480390092029-03-24U-539
N022525-0048039009*PED2029-09-24Pediatric extension

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 5 · 164 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N022525-001NAMENDA XR7MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022525-002NAMENDA XR14MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022525-003NAMENDA XR21MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022525-004NAMENDA XR28MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022525-001NAMENDA XR7MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE, EXTENDED RELEASE / ORALRLD2010-06-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022525-002NAMENDA XR14MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022525-003NAMENDA XR21MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022525-004NAMENDA XR28MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-2131067a03dcf5…
2025-08-23 18:47 UTC2025-08N022525-001NAMENDA XR7MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE, EXTENDED RELEASE / ORALRLD2010-06-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022525-002NAMENDA XR14MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022525-003NAMENDA XR21MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022525-004NAMENDA XR28MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022525-001NAMENDA XR7MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022525-002NAMENDA XR14MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022525-003NAMENDA XR21MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022525-004NAMENDA XR28MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022525-001NAMENDA XR7MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022525-002NAMENDA XR14MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022525-003NAMENDA XR21MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022525-004NAMENDA XR28MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022525-001NAMENDA XR7MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE, EXTENDED RELEASE / ORALRLD2010-06-2103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022525-002NAMENDA XR14MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-2103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022525-003NAMENDA XR21MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-2103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022525-004NAMENDA XR28MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-2103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022525-001NAMENDA XR7MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE, EXTENDED RELEASE / ORALRLD2010-06-212680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022525-002NAMENDA XR14MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-212680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022525-003NAMENDA XR21MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-212680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022525-004NAMENDA XR28MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-212680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022525-001NAMENDA XR7MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE, EXTENDED RELEASE / ORALRLD2010-06-215bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022525-002NAMENDA XR14MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-215bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022525-003NAMENDA XR21MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-215bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022525-004NAMENDA XR28MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-215bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N022525-001NAMENDA XR7MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N022525-002NAMENDA XR14MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N022525-003NAMENDA XR21MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N022525-004NAMENDA XR28MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N022525-001NAMENDA XR7MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21d06236e962d9…
2024-10-29 15:01 UTC2024-10N022525-002NAMENDA XR14MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21d06236e962d9…
2024-10-29 15:01 UTC2024-10N022525-003NAMENDA XR21MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21d06236e962d9…
2024-10-29 15:01 UTC2024-10N022525-004NAMENDA XR28MGCAPSULE, EXTENDED RELEASE / ORALRLD2010-06-21d06236e962d9…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 108 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N022525-002AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N022525-003AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N022525-004AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N022525-002AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N022525-003AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N022525-004AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N022525-002AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N022525-003AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N022525-004AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022525-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022525-002AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022525-003AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022525-004AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N022525-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N022525-002AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N022525-003AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N022525-004AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N022525-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N022525-002AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N022525-003AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N022525-004AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N022525-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12N022525-002AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12N022525-003AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12N022525-004AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N022525-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N022525-002AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N022525-003AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N022525-004AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N022525-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12N022525-002AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12N022525-003AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12N022525-004AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N022525-001AB187673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N022525-002AB187673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N022525-003AB187673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N022525-004AB187673890dc5c…
2021-03-12 10:30 UTC2021-03N022525-001AB15aa47cf7b7d7…
2021-03-12 10:30 UTC2021-03N022525-002AB15aa47cf7b7d7…
2021-03-12 10:30 UTC2021-03N022525-003AB15aa47cf7b7d7…

Observed Orange Book patent history#

Patent history page 1 of 17 · 664 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N022525-00180390092029-03-24U-5392011-11-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022525-0018039009*PED2029-09-24Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022525-00280390092029-03-24U-539011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022525-0028039009*PED2029-09-24Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022525-00380390092029-03-24U-539011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022525-0038039009*PED2029-09-24Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022525-00480390092029-03-24U-539011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022525-0048039009*PED2029-09-24Pediatric extension011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022525-00180390092029-03-24U-5392011-11-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022525-0018039009*PED2029-09-24Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022525-00280390092029-03-24U-53931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022525-0028039009*PED2029-09-24Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022525-00380390092029-03-24U-53931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022525-0038039009*PED2029-09-24Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022525-00480390092029-03-24U-53931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022525-0048039009*PED2029-09-24Pediatric extension31067a03dcf5…
2025-08-23 18:47 UTC2025-08N022525-00180390092029-03-24U-5392011-11-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022525-0018039009*PED2029-09-24Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022525-00280390092029-03-24U-5396a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022525-0028039009*PED2029-09-24Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022525-00380390092029-03-24U-5396a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022525-0038039009*PED2029-09-24Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022525-00480390092029-03-24U-5396a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022525-0048039009*PED2029-09-24Pediatric extension6a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022525-00180390092029-03-24U-5392011-11-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022525-0018039009*PED2029-09-24Pediatric extensionfd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022525-00280390092029-03-24U-539fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022525-0028039009*PED2029-09-24Pediatric extensionfd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022525-00380390092029-03-24U-539fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022525-0038039009*PED2029-09-24Pediatric extensionfd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022525-00480390092029-03-24U-539fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022525-0048039009*PED2029-09-24Pediatric extensionfd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022525-00180390092029-03-24U-5392011-11-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022525-0018039009*PED2029-09-24Pediatric extensionb8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022525-00280390092029-03-24U-539b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022525-0028039009*PED2029-09-24Pediatric extensionb8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022525-00380390092029-03-24U-539b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022525-0038039009*PED2029-09-24Pediatric extensionb8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022525-00480390092029-03-24U-539b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022525-0048039009*PED2029-09-24Pediatric extensionb8a1b40f171c…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
60505-6210-3EA - Each60505-62102e01f522-1c5c-4fae-a742-1c22d428061612019-06-19

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
60505-6210-36050562100330 CAPSULE, EXTENDED RELEASE in 1 BOTTLE (60505-6210-3) 2019-05-090000-00-00NoNoCurrent