Ivabradine

Product NDC
60687-862
Requested package NDC
60687-862-21
11-digit product format
606870862
Labeler code
60687
Product ID
60687-862_38e0b27f-e2e8-d69e-e063-6394a90a21dd
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Ivabradine
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
American Health Packaging
Application
ANDA213366
Marketing category
ANDA
Marketing start
2025-07-01
Substance
IVABRADINE HYDROCHLORIDE
Active strength
5 mg/1
Pharmacologic classes
Hyperpolarization-activated Cyclic Nucleotide-gated Channel Antagonists [MoA], Hyperpolarization-activated Cyclic Nucleotide-gated Channel Blocker [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A213366-001IVABRADINE HYDROCHLORIDEIVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-05
A213366-002IVABRADINE HYDROCHLORIDEIVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A213366-001AB
A213366-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 52 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-05011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-0531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-056a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-05fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-05b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-0503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-052680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-055bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-05d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-05d06236e962d9…
2024-10-29 15:01 UTC2024-10A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-0579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-05301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-051e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-058072bd15b7f6…
2024-05-31 18:47 UTC2024-05A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-058072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-056a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-056a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-051c564ffb4f44…
2024-02-18 07:12 UTC2024-02A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-051c564ffb4f44…
2023-12-20 04:57 UTC2023-12A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-05ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-05ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-05a72a2bbeb626…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-05a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-059b2671bbb829…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-059b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A213366-001IVABRADINE HYDROCHLORIDEEQ 5MG BASETABLET / ORALAB2022-10-05a67488948f0b…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A213366-002IVABRADINE HYDROCHLORIDEEQ 7.5MG BASETABLET / ORALAB2022-10-05a67488948f0b…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 52 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A213366-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213366-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213366-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213366-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A213366-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213366-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213366-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213366-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213366-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213366-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213366-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213366-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213366-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213366-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213366-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213366-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213366-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213366-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A213366-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A213366-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213366-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213366-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213366-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213366-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213366-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213366-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A213366-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A213366-002AB18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A213366-001AB16a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A213366-002AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A213366-001AB11c564ffb4f44…
2024-02-18 07:12 UTC2024-02A213366-002AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A213366-001AB1ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12A213366-002AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A213366-001AB1a72a2bbeb626…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A213366-002AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A213366-001AB19b2671bbb829…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A213366-002AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A213366-001AB1a67488948f0b…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A213366-002AB1a67488948f0b…

Additional Listing Data#

Finished product
Yes
Brand name base
Ivabradine
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
IVABRADINE HYDROCHLORIDE5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
TP19837BZKInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1649485Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
e881a1ac-9221-4682-939f-966679cfe286Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
eebd3ed3-f483-47f1-9e64-83ee4010ac6eProduct name520260130

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
60687-862-11Ivabradine1 in 1 BLISTER PACKTABLET, FILM COATED12
60687-862-21Ivabradine30 in 1 CARTONTABLET, FILM COATED302

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
60687-862-11EA - Each60687-862901a45db-2c38-4750-ab95-d113c28160d712025-07-08
60687-862-21EA - Each60687-8621bd9b47a-de31-44c1-a20b-7bd54fc0498512025-07-08

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
IvabradineIVABRADINEAmerican Health Packaginge881a1ac-9221-4682-939f-966679cfe2862025-07-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213366
application number: ANDA213366
ndc (package): 60687-862-21
ndc (product): 60687-862
ndc11 (package): 60687086221
IvabradineIVABRADINECamber Pharmaceuticals, Inc.602d1c55-0e4d-452a-a087-888fdbaa75682024-04-30Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213366
application number: ANDA213366

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1649485ivabradine 5 MG Oral TabletPSNe881a1ac-9221-4682-939f-966679cfe2862
1649485ivabradine 5 MG Oral TabletSCDe881a1ac-9221-4682-939f-966679cfe2862
1649485ivabradine 5 MG (as ivabradine HCl 5.39 MG) Oral TabletSYe881a1ac-9221-4682-939f-966679cfe2862

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
60687-862-216068708622130 BLISTER PACK in 1 CARTON (60687-862-21) / 1 TABLET, FILM COATED in 1 BLISTER PACK (60687-862-11) 30 blister pack2025-07-01NoNoCurrent