Irinotecan Hydrochloride

Product NDC
61703-349
11-digit product format
617030349
Labeler code
61703
Product ID
61703-349_9c52ca8e-58dd-4117-a5bc-f277e79abb19
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Irinotecan Hydrochloride
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
Hospira, Inc.
Application
ANDA077915
Marketing category
ANDA
Marketing start
2008-02-27
Substance
IRINOTECAN HYDROCHLORIDE
Active strength
20 mg/mL
Pharmacologic classes
Topoisomerase Inhibitor [EPC], Topoisomerase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A077915-001IRINOTECAN HYDROCHLORIDEIRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27
A077915-002IRINOTECAN HYDROCHLORIDEIRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A077915-001AP
A077915-002AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-2731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-2731067a03dcf5…
2025-08-23 18:47 UTC2025-08A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-276a471c1ec25d…
2025-08-23 18:47 UTC2025-08A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-276a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-2703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-2703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-272680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-272680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-275bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-275bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27d06236e962d9…
2024-10-29 15:01 UTC2024-10A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-2779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-2779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-271e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-271e350fbaab3a…
2024-05-31 18:47 UTC2024-05A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-278072bd15b7f6…
2024-05-31 18:47 UTC2024-05A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-278072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-275c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-275c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-275d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-275d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-274b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-274b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-2774a2ff9319b5…
2019-12-13 00:20 UTC2019-12A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-2774a2ff9319b5…
2022-03-09 01:35 UTC2022-03A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A077915-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27782e0a99824c…
2021-12-28 21:50 UTC2021-12A077915-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A077915-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A077915-002AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A077915-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A077915-002AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A077915-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A077915-002AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A077915-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A077915-002AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A077915-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A077915-002AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A077915-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A077915-002AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A077915-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A077915-002AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A077915-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A077915-002AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A077915-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A077915-002AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A077915-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A077915-002AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A077915-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A077915-002AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A077915-001AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A077915-002AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A077915-001AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A077915-002AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A077915-001AP18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A077915-002AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A077915-001AP15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A077915-002AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A077915-001AP15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A077915-002AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A077915-001AP14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A077915-002AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A077915-001AP174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A077915-002AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A077915-001AP1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A077915-002AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A077915-001AP1782e0a99824c…
2021-12-28 21:50 UTC2021-12A077915-002AP1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
Irinotecan Hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
IRINOTECAN HYDROCHLORIDE20 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
042LAQ1IISInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1726319Internal RxNorm lookup
1726324Internal RxNorm lookup
1726492Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
5c527c2e-9062-4afe-dbbb-f650db3a340fAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
cfce77d6-e90b-6280-14b8-e6a66a38ebbcProduct name720210525
077454e2-2db8-411c-801d-08d70e0bebabProduct name120151116

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
61703-349-09Irinotecan Hydrochloride5 mL in 1 VIAL, SINGLE-DOSEINJECTION, SOLUTION526
61703-349-09Irinotecan Hydrochloride1 in 1 CARTONINJECTION, SOLUTION126
61703-349-16Irinotecan Hydrochloride1 in 1 CARTONINJECTION, SOLUTION126
61703-349-16Irinotecan Hydrochloride2 mL in 1 VIAL, SINGLE-DOSEINJECTION, SOLUTION226
61703-349-36Irinotecan Hydrochloride25 mL in 1 VIAL, SINGLE-DOSEINJECTION, SOLUTION2526
61703-349-36Irinotecan Hydrochloride1 in 1 CARTONINJECTION, SOLUTION126

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
61703-349-09ML - Milliliter61703-349702a7263-7588-4898-a86b-1481f5afcf8512012-07-24
61703-349-16ML - Milliliter61703-349113e0a48-d030-4157-8268-ca6b195c36d212012-07-24
61703-349-36ML - Milliliter61703-349288b5ce0-e60f-4147-a82b-4974ef554bfb12012-07-24

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
61703-349IRINOTECAN HYDROCHLORIDE INJECTION, SOLUTION [HOSPIRA, INC.]25Current NDC, Legacy NDC, 6 package rows20250121_5c527c2e-9062-4afe-dbbb-f650db3a340f.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Irinotecan HydrochlorideIRINOTECAN HYDROCHLORIDEHospira, Inc.5c527c2e-9062-4afe-dbbb-f650db3a340f2025-11-03Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 077915
application number: ANDA077915
ndc (product): 61703-349

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1726324irinotecan HCl 100 MG in 5 ML InjectionPSN5c527c2e-9062-4afe-dbbb-f650db3a340f26
1726319irinotecan HCl 40 MG in 2 ML InjectionPSN5c527c2e-9062-4afe-dbbb-f650db3a340f26
1726492irinotecan HCl 500 MG in 25 ML InjectionPSN5c527c2e-9062-4afe-dbbb-f650db3a340f26
17263192 ML irinotecan hydrochloride 20 MG/ML InjectionSCD5c527c2e-9062-4afe-dbbb-f650db3a340f26
172649225 ML irinotecan hydrochloride 20 MG/ML InjectionSCD5c527c2e-9062-4afe-dbbb-f650db3a340f26
17263245 ML irinotecan hydrochloride 20 MG/ML InjectionSCD5c527c2e-9062-4afe-dbbb-f650db3a340f26
1726324irinotecan HCl 100 MG per 5 ML InjectionSY5c527c2e-9062-4afe-dbbb-f650db3a340f26
1726319irinotecan HCl 40 MG per 2 ML InjectionSY5c527c2e-9062-4afe-dbbb-f650db3a340f26
1726492irinotecan HCl 500 MG per 25 ML InjectionSY5c527c2e-9062-4afe-dbbb-f650db3a340f26

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
61703-349-09617030349091 VIAL, SINGLE-DOSE in 1 CARTON (61703-349-09) / 5 mL in 1 VIAL, SINGLE-DOSE2008-02-270000-00-00NoNoCurrent
61703-349-16617030349161 VIAL, SINGLE-DOSE in 1 CARTON (61703-349-16) / 2 mL in 1 VIAL, SINGLE-DOSE2008-02-270000-00-00NoNoCurrent
61703-349-36617030349361 VIAL, SINGLE-DOSE in 1 CARTON (61703-349-36) / 25 mL in 1 VIAL, SINGLE-DOSE2008-02-270000-00-00NoNoCurrent