Amantadine Hydrochloride

Product NDC
62135-011
11-digit product format
621350011
Labeler code
62135
Product ID
62135-011_45c62a1b-f162-d3cb-e063-6394a90a7dbf
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Amantadine Hydrochloride
Dosage form
SOLUTION
Route
ORAL
Labeler
Chartwell RX, LLC
Application
ANDA074028
Marketing category
ANDA
Marketing start
1993-06-28
Substance
AMANTADINE HYDROCHLORIDE
Active strength
100 mg/10mL
Pharmacologic classes
Influenza A M2 Protein Inhibitor [EPC], M2 Protein Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A074028-001AMANTADINE HYDROCHLORIDEAMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A074028-001AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-285bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-2879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-281e350fbaab3a…
2024-05-31 18:47 UTC2024-05A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-288072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-285c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-285d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-284b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-2874a2ff9319b5…
2022-03-09 01:35 UTC2022-03A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-2887673890dc5c…
2021-03-12 10:30 UTC2021-03A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-285aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-288869cabd3fbd…
2020-11-12 02:37 UTC2020-11A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28c0c555d07b60…
2019-12-14 00:12 UTC2019-12A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-283f01610625f2…
2019-09-15 20:21 UTC2019-09A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28b00525d2431f…
2019-07-19 19:46 UTC2019-07A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-286a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-281c564ffb4f44…
2023-12-20 04:57 UTC2023-12A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-289b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-283f0d92c62455…
2023-05-13 08:27 UTC2023-05A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28053a50430f4f…
2023-01-26 05:58 UTC2023-01A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-283bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-283a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A074028-001AMANTADINE HYDROCHLORIDE50MG/5MLSYRUP / ORALAARS1993-06-28cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A074028-001AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074028-001AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08A074028-001AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074028-001AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074028-001AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074028-001AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074028-001AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074028-001AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074028-001AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A074028-001AA1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A074028-001AA179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A074028-001AA1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A074028-001AA11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A074028-001AA18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A074028-001AA15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A074028-001AA15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A074028-001AA14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A074028-001AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A074028-001AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A074028-001AA1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A074028-001AA187673890dc5c…
2021-03-12 10:30 UTC2021-03A074028-001AA15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A074028-001AA18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A074028-001AA1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A074028-001AA13f01610625f2…
2019-09-15 20:21 UTC2019-09A074028-001AA1b00525d2431f…
2019-07-19 19:46 UTC2019-07A074028-001AA1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A074028-001AA16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A074028-001AA11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A074028-001AA1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A074028-001AA1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A074028-001AA19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A074028-001AA1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A074028-001AA13f0d92c62455…
2023-05-13 08:27 UTC2023-05A074028-001AA1053a50430f4f…
2023-01-26 05:58 UTC2023-01A074028-001AA13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A074028-001AA13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A074028-001AA1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A074028-001AA1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A074028-001AA1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Amantadine Hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
AMANTADINE HYDROCHLORIDE100 mg/10mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
M6Q1EO9TD0Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
849385Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
52aa093c-82cc-4d81-b072-86a2b8adc9c5Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
519d6abc-639d-2962-cced-abbf8b16aad4Product name720250401
82f46845-b4c7-48da-a389-ba5721b956c9Product name220250325
d2c037c0-5ebf-d224-252f-2549922c21c7Product name720240208
b7b57a62-2f7f-1a22-2cb2-eaa5c08d4721Product name220220224
14e11aaf-885f-472f-a02a-c6a3f28df907Product name120180515
82f46845-b4c7-48da-a389-ba5721b956c9Product name120171103

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
62135-011-24Amantadine Hydrochloride10 in 1 TRAYSOLUTION105
62135-011-24Amantadine Hydrochloride2 in 1 BOXSOLUTION25
62135-011-59Amantadine Hydrochloride10 mL in 1 CUP, UNIT-DOSESOLUTION105

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
62135-011-24ML - Milliliter62135-0112f4aac9c-d2f9-4aeb-8d91-0829612569cc12024-08-12
62135-011-59ML - Milliliter62135-011cad6c540-fc49-433b-9918-b5ac13bb929912024-08-12

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
62135-011AMANTADINE HYDROCHLORIDE SOLUTION [CHARTWELL RX, LLC]4Current NDC, 3 package rows20240524_52aa093c-82cc-4d81-b072-86a2b8adc9c5.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Amantadine HydrochlorideAMANTADINE HYDROCHLORIDEChartwell Governmental & Specialty RX, LLC.3c448cb3-7996-4a83-a9ad-23a00a431fbe2025-12-19Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074028
application number: ANDA074028
Amantadine HydrochlorideAMANTADINE HYDROCHLORIDEChartwell RX, LLC52aa093c-82cc-4d81-b072-86a2b8adc9c52025-12-12Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074028
application number: ANDA074028
ndc (product): 62135-011

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
849385amantadine HCl 50 MG in 5 mL Oral SolutionPSN52aa093c-82cc-4d81-b072-86a2b8adc9c55
849385amantadine hydrochloride 10 MG/ML Oral SolutionSCD52aa093c-82cc-4d81-b072-86a2b8adc9c55
849385amantadine hydrochloride 100 MG per 10 ML Oral SolutionSY52aa093c-82cc-4d81-b072-86a2b8adc9c55
849385amantadine hydrochloride 50 MG per 5 ML Oral SolutionSY52aa093c-82cc-4d81-b072-86a2b8adc9c55

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
62135-011-24621350011242 TRAY in 1 BOX (62135-011-24) / 10 CUP, UNIT-DOSE in 1 TRAY / 10 mL in 1 CUP, UNIT-DOSE (62135-011-59) 2 tray1993-06-28NoNoCurrent
62135-011-596213500115910 mL in 1 CUP, UNIT-DOSE10 mlHistorical