HYDROXYZINE HYDROCHLORIDE

Product NDC
62135-050
11-digit product format
621350050
Labeler code
62135
Product ID
62135-050_25117412-3663-105d-e063-6394a90a0d64
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
HYDROXYZINE HYDROCHLORIDE
Dosage form
SYRUP
Route
ORAL
Labeler
Chartwell RX, LLC
Application
ANDA087294
Marketing category
ANDA
Marketing start
1982-04-12
Substance
HYDROXYZINE DIHYDROCHLORIDE
Active strength
50 mg/25mL
Pharmacologic classes
Antihistamine [EPC], Histamine Receptor Antagonists [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A087294-001HYDROXYZINE HYDROCHLORIDEHYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A087294-001AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-1231067a03dcf5…
2025-08-23 18:47 UTC2025-08A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-126a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-1203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-122680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-125bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-1279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-121e350fbaab3a…
2024-05-31 18:47 UTC2024-05A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-128072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-125c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-125d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-124b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARS1982-04-1274a2ff9319b5…
2022-03-09 01:35 UTC2022-03A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARS1982-04-1287673890dc5c…
2021-03-12 10:30 UTC2021-03A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARS1982-04-125aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARS1982-04-128869cabd3fbd…
2020-11-12 02:37 UTC2020-11A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARS1982-04-12c0c555d07b60…
2019-12-14 00:12 UTC2019-12A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARS1982-04-123f01610625f2…
2019-09-15 20:21 UTC2019-09A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARS1982-04-12b00525d2431f…
2019-07-19 19:46 UTC2019-07A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARS1982-04-12ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-126a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-121c564ffb4f44…
2023-12-20 04:57 UTC2023-12A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-129b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-123f0d92c62455…
2023-05-13 08:27 UTC2023-05A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12053a50430f4f…
2023-01-26 05:58 UTC2023-01A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-123bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-123a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A087294-001HYDROXYZINE HYDROCHLORIDE10MG/5MLSYRUP / ORALAARLD, RS1982-04-12cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A087294-001AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A087294-001AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08A087294-001AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A087294-001AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A087294-001AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A087294-001AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A087294-001AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A087294-001AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A087294-001AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A087294-001AA1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A087294-001AA179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A087294-001AA1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A087294-001AA11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A087294-001AA18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A087294-001AA15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A087294-001AA15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A087294-001AA14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A087294-001AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A087294-001AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A087294-001AA1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A087294-001AA187673890dc5c…
2021-03-12 10:30 UTC2021-03A087294-001AA15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A087294-001AA18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A087294-001AA1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A087294-001AA13f01610625f2…
2019-09-15 20:21 UTC2019-09A087294-001AA1b00525d2431f…
2019-07-19 19:46 UTC2019-07A087294-001AA1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A087294-001AA16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A087294-001AA11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A087294-001AA1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A087294-001AA1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A087294-001AA19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A087294-001AA1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A087294-001AA13f0d92c62455…
2023-05-13 08:27 UTC2023-05A087294-001AA1053a50430f4f…
2023-01-26 05:58 UTC2023-01A087294-001AA13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A087294-001AA13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A087294-001AA1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A087294-001AA1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A087294-001AA1cb3db0bc1861…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
HYDROXYZINE HYDROCHLORIDEHYDROXYZINE HYDROCHLORIDEChartwell Governmental & Specialty RX, LLC.0de7a377-7a8f-4119-b172-1eadb4b7e1be2025-11-11Warnings, Adverse reactionsExact identifier
application applno (ANDA): 087294
application number: ANDA087294
HYDROXYZINE HYDROCHLORIDEHYDROXYZINE HYDROCHLORIDEChartwell RX, LLC53b2d731-f38a-47c0-9e5c-abd3b45e2fe12024-10-22Warnings, Adverse reactionsExact identifier
application applno (ANDA): 087294
application number: ANDA087294
ndc (product): 62135-050
Hydroxyzine HydrochlorideHYDROXYZINE HYDROCHLORIDEProficient Rx LPbcddc5ce-6cfb-4a09-8e6c-c956b65e31882022-10-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 087294
application number: ANDA087294

Additional Listing Data#

Finished product
Yes
Brand name base
HYDROXYZINE HYDROCHLORIDE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
HYDROXYZINE DIHYDROCHLORIDE50 mg/25mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
76755771U3Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
995241Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
53b2d731-f38a-47c0-9e5c-abd3b45e2fe1Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
57311cfb-679a-da1a-b70c-8757f7fc431aProduct name420250516
aa1826f4-97c1-4705-bdf0-3bc7d234e618Product name220190618
75cb12ee-8eb2-4f1a-a332-5743a5d0da41Product name120151110
3ca5f78b-43dc-30fe-8014-55b922af52b3Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
62135-050-24HYDROXYZINE HYDROCHLORIDE2 in 1 BOXSYRUP23
62135-050-24HYDROXYZINE HYDROCHLORIDE10 in 1 TRAYSYRUP103
62135-050-52HYDROXYZINE HYDROCHLORIDE25 mL in 1 CUPSYRUP253

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
62135-050-24ML - Milliliter62135-05010ab8d7b-29c6-4507-a58d-7ab1ae23f33a12024-11-05
62135-050-52ML - Milliliter62135-05068d32085-f93b-4219-af78-5fe63d1d73e312024-11-05

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
62135-050HYDROXYZINE HYDROCHLORIDE SYRUP [CHARTWELL RX, LLC]3Current NDC, 3 package rows20241024_53b2d731-f38a-47c0-9e5c-abd3b45e2fe1.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
995241hydrOXYzine HCl 10 MG in 5 mL Oral SolutionPSN53b2d731-f38a-47c0-9e5c-abd3b45e2fe13
995241hydroxyzine hydrochloride 2 MG/ML Oral SolutionSCD53b2d731-f38a-47c0-9e5c-abd3b45e2fe13
995241hydroxyzine hydrochloride 10 MG per 5 ML Oral SolutionSY53b2d731-f38a-47c0-9e5c-abd3b45e2fe13

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
62135-050-24621350050242 TRAY in 1 BOX (62135-050-24) / 10 CUP in 1 TRAY / 25 mL in 1 CUP (62135-050-52) 2 tray2024-09-23NoNoCurrent
62135-050-526213500505225 mL in 1 CUP25 mlHistorical